Assessment of Genotoxicity of Methyl Parathion in Zebrafish by Use of the Micronucleus Test

It was aimed to assessment the genotoxic potential of methyl parathion (MP) on zebrafish (Danio rerio), by using micronucleus test. Twenty adult zebrafish were exposed to three different concentrations (1, 1.5, 3 mg/L) of MP for 96 h. In addition to negative controls, cyclophosphamide monohydrate (4mg/L) was used as a reference genotoxic agent for positive controls. Peripheral blood samples were collected from all of the specimens and stained with acridine orange. The immature, polychromatic (PCEs) and mature, monochromatic (MCEs) erythrocytes were identified by their staining intensity and scored. The ratio of PCEs/MCEs were calculated, analyzed and compared.nbsp In parallel with increased concentrations of MP, the micronucleated PCEs were increased in number, while a decline in the ratio of the PCEs/MCEs was recorded. The results revealed that MP has a short-time genotoxic effects on zebrafish.nbs

Green ICT (Information and Communication Technologies): A Review of Academic and Practitioner Perspectives

Green ICT (Information and Communication Technologies): A Review of Academic and Practitioner Perspective

The Effects of Dioctyl Adipate (DOA) on The Liver Histology of Labidochromis caeruleus Fryer, 1956 (Cichlidae, Teleostei)

WOS: 000281800400004Although dioctyl adipate (DOA. C(22)H(42)O(4)) is one of the most common plasticizers that are used for polymerization, the ecotoxicological effects of it is not well known. From this point of view, aim of this preliminary investigation was to analyze the histopathological changes in the liver of Labidochromis caeruleus (yellow princess), exposed to 0.75 ppm DOA for 30 days. When compared to controls, the most prominent changes occurred in the DOA exposed group were noted as a significant steatosis (fat deposisiton), fibrosis and expanding necrotic areas. The dilatation of sinusoids and central veins, poikilocytosis, and hemorrhage were also observed. The data presented in this study shows that. DOA is a hepatotoxic chemical at least for Labidocromis caerulous