8 research outputs found
A comparison of multiage education and graded education in the areas of academics, social skills and attitudes of participants
This study compared the effects of multiage education and graded education on academic performance, social skills development and parent, student and teacher attitudes toward school.
The 34 multiage students and the 27 graded students were assessed through curriculum based tests and informal reading inventories. Statistical analyses were completed A significant difference was found.
Both groups of students completed a social skills development survey. Cafeteria/playground aides were surveyed and discipline referrals were examined to find the percentage of students in each group who received a detention for a discipline violation. Data was collected, and statistically analyzed. No significant difference was found.
The parents of both groups of students completed a survey about their impressions of the education of their children. Both groups of students completed a survey about their attitudes toward school. The two multiage teachers and the two graded teachers added information through discussion and interview to determine their altitudes toward their respective educational programs. Data was statistically analyzed. No significant difference was found
Developing An Undergraduate Student Research Conference In Business: A Model
AACSB accreditation, a student-centered mission statement, and the continuous quality improvement that most educators engage in have resulted in an increase in student research projects. This presented an opportunity to develop a venue for students to showcase their research. The paper describes a model for a student research conference in business that has resulted in increased student engagement and an increase in student-faculty research collaboration
Undergraduate Research As A Fate Accompli: Innovation And Evolution Of A Student Conference In Business
The benefits of undergraduate research continue to receive academic attention and it is becoming an engaged learning practice present on many college campuses today. As research participation grows, an opportunity exists to showcase the work being accomplished and to use this public presentation to foster a culture of undergraduate research on campus, lobby for additional funding, and increase student and faculty participation. We describe the innovation and evolution of a student conference in business, sharing lessons learned and measureable results for the ten years this conference has been in place
Social Media and the Fear of Missing Out: Scale Development and Assessment
For many, viewing social media causes them to relate their own lives to what they are seeing or reading, resulting in feelings that they are somehow missing out. It is suggested that the fear of missing out influences decision making and behavior. The current research explores the measurement of FOMO, focusing on scale development and validation. Using extant scales for inadequacy, irritability, anxiety, and self- esteem, a list of items (n=37), postulated to measure FOMO, was created. In addition to the scale items, questions to assess behavioral and demographic characteristic were included. A pre-test of the survey instrument was conducted (n=30). The final survey was administered electronically, resulting in a useable sample of n=202. Principal components analysis resulted in a 10 item, 3-factor solution explaining 71% of the overall variance. The three factors performed reasonably well all with Cronbach’s alpha above or near Nunnally’s suggested .70 (Nunnally, 1978). Using the newly created scale, FOMO scores were calculated for each respondent. Results suggest significant differences in social media consumption across levels of FOMO. Results also suggest significant differences in the use of particular social media based on ones level of FOMO. Limitations include the sample and it is suggested that future research, including confirmatory factor analysis, should be conducted
Building brand community membership within organizations: a viable internal branding alternative?
Torch Awards for Marketplace Ethics: Providing Students “Hands ON” Experience with Marketing Ethics
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A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit.
ImportanceCoenzyme Q10 (CoQ10), an antioxidant that supports mitochondrial function, has been shown in preclinical Parkinson disease (PD) models to reduce the loss of dopamine neurons, and was safe and well tolerated in early-phase human studies. A previous phase II study suggested possible clinical benefit.ObjectiveTo examine whether CoQ10 could slow disease progression in early PD.Design, setting, and participantsA phase III randomized, placebo-controlled, double-blind clinical trial at 67 North American sites consisting of participants 30 years of age or older who received a diagnosis of PD within 5 years and who had the following inclusion criteria: the presence of a rest tremor, bradykinesia, and rigidity; a modified Hoehn and Yahr stage of 2.5 or less; and no anticipated need for dopaminergic therapy within 3 months. Exclusion criteria included the use of any PD medication within 60 days, the use of any symptomatic PD medication for more than 90 days, atypical or drug-induced parkinsonism, a Unified Parkinson's Disease Rating Scale (UPDRS) rest tremor score of 3 or greater for any limb, a Mini-Mental State Examination score of 25 or less, a history of stroke, the use of certain supplements, and substantial recent exposure to CoQ10. Of 696 participants screened, 78 were found to be ineligible, and 18 declined participation.InterventionsThe remaining 600 participants were randomly assigned to receive placebo, 1200 mg/d of CoQ10, or 2400 mg/d of CoQ10; all participants received 1200 IU/d of vitamin E.Main outcomes and measuresParticipants were observed for 16 months or until a disability requiring dopaminergic treatment. The prospectively defined primary outcome measure was the change in total UPDRS score (Parts I-III) from baseline to final visit. The study was powered to detect a 3-point difference between an active treatment and placebo.ResultsThe baseline characteristics of the participants were well balanced, the mean age was 62.5 years, 66% of participants were male, and the mean baseline total UPDRS score was 22.7. A total of 267 participants required treatment (94 received placebo, 87 received 1200 mg/d of CoQ10, and 86 received 2400 mg/d of CoQ10), and 65 participants (29 who received placebo, 19 who received 1200 mg/d of CoQ10, and 17 who received 2400 mg/d of CoQ10) withdrew prematurely. Treatments were well tolerated with no safety concerns. The study was terminated after a prespecified futility criterion was reached. At study termination, both active treatment groups showed slight adverse trends relative to placebo. Adjusted mean changes (worsening) in total UPDRS scores from baseline to final visit were 6.9 points (placebo), 7.5 points (1200 mg/d of CoQ10; P = .49 relative to placebo), and 8.0 points (2400 mg/d of CoQ10; P = .21 relative to placebo).Conclusions and relevanceCoenzyme Q10 was safe and well tolerated in this population, but showed no evidence of clinical benefit.Trial registrationclinicaltrials.gov Identifier: NCT00740714
A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit
Coenzyme Q10 (CoQ10), an antioxidant that supports mitochondrial function, has been shown in preclinical Parkinson disease (PD) models to reduce the loss of dopamine neurons, and was safe and well tolerated in early-phase human studies. A previous phase II study suggested possible clinical benefit.
To examine whether CoQ10 could slow disease progression in early PD.
A phase III randomized, placebo-controlled, double-blind clinical trial at 67 North American sites consisting of participants 30 years of age or older who received a diagnosis of PD within 5 years and who had the following inclusion criteria: the presence of a rest tremor, bradykinesia, and rigidity; a modified Hoehn and Yahr stage of 2.5 or less; and no anticipated need for dopaminergic therapy within 3 months. Exclusion criteria included the use of any PD medication within 60 days, the use of any symptomatic PD medication for more than 90 days, atypical or drug-induced parkinsonism, a Unified Parkinson's Disease Rating Scale (UPDRS) rest tremor score of 3 or greater for any limb, a Mini-Mental State Examination score of 25 or less, a history of stroke, the use of certain supplements, and substantial recent exposure to CoQ10. Of 696 participants screened, 78 were found to be ineligible, and 18 declined participation.
The remaining 600 participants were randomly assigned to receive placebo, 1200 mg/d of CoQ10, or 2400 mg/d of CoQ10; all participants received 1200 IU/d of vitamin E.
Participants were observed for 16 months or until a disability requiring dopaminergic treatment. The prospectively defined primary outcome measure was the change in total UPDRS score (Parts I-III) from baseline to final visit. The study was powered to detect a 3-point difference between an active treatment and placebo.
The baseline characteristics of the participants were well balanced, the mean age was 62.5 years, 66% of participants were male, and the mean baseline total UPDRS score was 22.7. A total of 267 participants required treatment (94 received placebo, 87 received 1200 mg/d of CoQ10, and 86 received 2400 mg/d of CoQ10), and 65 participants (29 who received placebo, 19 who received 1200 mg/d of CoQ10, and 17 who received 2400 mg/d of CoQ10) withdrew prematurely. Treatments were well tolerated with no safety concerns. The study was terminated after a prespecified futility criterion was reached. At study termination, both active treatment groups showed slight adverse trends relative to placebo. Adjusted mean changes (worsening) in total UPDRS scores from baseline to final visit were 6.9 points (placebo), 7.5 points (1200 mg/d of CoQ10; P = .49 relative to placebo), and 8.0 points (2400 mg/d of CoQ10; P = .21 relative to placebo).
Coenzyme Q10 was safe and well tolerated in this population, but showed no evidence of clinical benefit.
clinicaltrials.gov Identifier: NCT00740714