11 research outputs found

    Fishers (Paraty, RJ) and fish manipulation time: a variable associated to the choice for consumption and sale

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    973975Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

    Fishers (paraty, Rj) And Fish Manipulation Time: A Variable Associated To The Choice For Consumption And Sale

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    [No abstract available]724973975Begossi, A., Richerson, P., The animal diet of families from Búzios Island (Brazil): An optimal foraging approach (1992) Journal of Human Ecology, 3, pp. 433-458Begossi, A., Hanazaki, N., Ramos, R., Food chain and the reasons for food taboos among Amazonian and Atlantic Forest fishers (Brazil) (2004) Ecological Applications, 14 (5), pp. 1334-1343. , http://dx.doi.org/10.1890/03-5072Begossi, A., Lopes, P.F., Oliveira, L.E.C., Nakano, H., Ecologia De Pescadores Artesanais Da Baía Da Ilha Grande (2010), São Carlos: RimaBegossi, A., Salyvonchyk, S.V., Nora, V., Lopes, P.F., Silvano, R.A.M., The Paraty artisanal fishery (southeastern Brazilian coast): Ethnoecology and management of a social-ecological system (SES) (2012) Journal of Ethnobiology and Ethnomedicine, 28 (1), p. 22. , http://dx.doi.org/10.1186/1746-4269-8-22Burger, O., Hamilton, M.J., Walker, R., The prey as patch model: Optimal handling of resources with diminishing returns (2005) Journal of Archaeological Science, 32, pp. 1147-1158. , http://dx.doi.org/10.1016/j.jas.2005.02.012Hames, R.B., Vickers, W.T., Optimal diet breadth theory as a model to explain variability in Amazonian hunting (1982) American Ethnologist, 9, pp. 358-379. , http://dx.doi.org/10.1525/ae.1982.9.2.02a00090Hanazaki, N., Begossi, A., Does fish still matter? Changes in the diet of two Brazilian fishing communities (2004) Ecology of Food and Nutrition, 42, pp. 279-301. , http://dx.doi.org/10.1080/03670240390229643Hanazaki, N., Begossi, A., Catfish and mullets: The food preferences and taboos of Caiçaras (Southern Atlantic Forest Coast, Brazil) (2006) Interciência, 31 (2), pp. 123-129Messer, E., Anthropological perspectives on diet (1984) Annual Review of Anthropology, 13, pp. 205-249. , http://dx.doi.org/10.1146/annurev.an.13.100184.001225Murrieta, R.S.S., Dufour, D.L., Siqueira, A., Food consumption and subsistence in three Caboclo populations on Marajó island, Amazonia, Brazil (1999) Human Ecology, 27, pp. 455-475. , http://dx.doi.org/10.1023/A:1018779624490Nehrer, R., Begossi, A., Fishing at Copacabana, Rio de Janeiro: Local strategies in a global city (2000) Ciência E Cultura, 52, pp. 26-30Pomeroy, R.S., Andrew, N., Small scale fishery management (2011), www.cabi.or

    Fishers (Paraty, RJ) and fish manipulation time: a variable associated to the choice for consumption and sale

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    When bones need to be removed from fish, especially when caring for children eating the fish, time is taken up to manipulate their food. The type of fish chosen by fishermen’s families is important because there is a dilemma between consuming or selling the catch; target species are often concentrated on commercial fish; and management processes often include periods where fishing is not allowed for some species, having potential impacts in the food security and nutrition of families. Fish manipulation time could also be a deciding factor in food choices and food security

    Effect of vitamin D supplementation alone on muscle function in postmenopausal women: a randomized, double-blind, placebo-controlled clinical trial

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    The present study investigates the effects of vitamin D on muscle function in postmenopausal women. It has been shown that vitamin D supplementation in postmenopausal women with hypovitaminosis D provides significant protective factor against sarcopenia, with significant increases in muscle strength and control of progressive loss of lean mass. We aimed to evaluate the effect of supplementation of vitamin D (VITD) alone on muscle function in younger postmenopausal women. In this double-blind, placebo-controlled clinical trial, 160 Brazilian postmenopausal women were randomized into two groups: VITD group consisting of patients receiving vitamin D3 1000 IU/day orally (n = 80) or placebo group (n = 80). Women with amenorrhea for more than 12 months and age 50-65 years, with a history of falls (previous 12 months), were included. The intervention time was 9 months, with assessments at two points, start and end. Lean mass was estimated by total-body dual-energy X-ray absorptiometry (DXA) and muscle strength by handgrip strength and chair rising test. The plasma concentrations of 25-hydroxyvitamin D [25(OH)D] were measured by high-performance liquid chromatography (HPLC). Statistical analysis was by intention to treat (ITT), using ANOVA, Student's t test, and Tukey's test. After 9 months, average values of 25(OH)D increased from 15.0 ± 7.5 to 27.5 ± 10.4 ng/ml (+45.4 %) in the VITD group and decreased from 16.9 ± 6.7 to 13.8 ± 6.0 ng/ml (-18.5 %) in the placebo group (p < 0.001). In the VITD group, there was significant increase in muscle strength (+25.3 %) of the lower limbs by chair rising test (p = 0.036). In women in the placebo group, there was considerable loss (-6.8 %) in the lean mass (p = 0.030). The supplementation of vitamin D alone in postmenopausal women provided significant protective factor against the occurrence of sarcopenia, with significant increases in muscle strength and control of progressive loss of lean mass

    &lt;b&gt;Síntese e modelagem molecular do novo derivado indolinônico como candidato a antiinflamatório COX-2 seletivo&lt;/b&gt;

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    &lt;p class="MsoNormal" style="margin: 0cm 0cm 0pt; line-height: normal; text-align: justify; mso-layout-grid-align: none;"&gt; Os fármacos antiinflamatórios são sabidamente os mais comercializados em todo o mundo, e apesar disto apresentam sérios efeitos colaterais, sobretudo no que se refere ao trato gastrintestinal. A descoberta de novos protótipos com atividade e segurança terapêutica melhoradas continua sendo uma busca constante. Com o advento da química computacional torna-se mais fácil o estudo teórico do comportamento fisiológico de uma nova substância bem como a compreensão do possível mecanismo de ação destas novas moléculas. Assim, através de modelos matemáticos de moléculas e receptores estudouse neste trabalho o composto I (1-(2,6- diclorofenil)indolin-2-ona) quanto à sua possibilidade de inibir seletivamente a isoforma COX-2 da enzima prostaglandina endoperóxido sintase (PGHS), e também as melhores posições para a introdução de grupamentos químicos e modificações moleculares. Palavras-chave: indolinônico; COX-2; antiinflamatório. &lt;/p&gt

    Síntese e modelagem molecular do novo derivado indolinônico como candidato a antiinflamatório COX-2 seletivo

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    Anti-inflammatory drugs are known to be the most widely-marketed drugs in the world, despite their serious side effects, mainly on the gastrointestinal tract. Thus, there are constant efforts to discover new prototypes with improved therapeutic activity and safety for the patient. Since the advent of the computational chemistry, the theoretical study of the physiological behavior of a new compound and hence an understanding of its supposed mechanism of action have been made a lot more accessible. Thus, molecule-receptor mathematical modeling was applied to compound I (1-(2,6-dichlorophenyl)indolin-2-one), to predict theoretically its ability to inhibit, selectively, the COX-2 isoform of prostaglandin endoperoxide synthase (PGHS-2), and the best positions to introduce chemical groups and to make molecular modifications.Os fármacos antiinflamatórios são sabidamente os mais comercializados em todo o mundo, e apesar disto apresentam sérios efeitos colaterais, sobretudo no que se refere ao trato gastrintestinal. A descoberta de novos protótipos com atividade e segurança terapêutica melhoradas continua sendo uma busca constante. Com o advento da química computacional torna-se mais fácil o estudo teórico do comportamento fisiológico de uma nova substância bem como a compreensão do possível mecanismo de ação destas novas moléculas. Assim, através de modelos matemáticos de moléculas e receptores estudouse neste trabalho o composto I (1-(2,6- diclorofenil)indolin-2-ona) quanto à sua possibilidade de inibir seletivamente a isoforma COX-2 da enzima prostaglandina endoperóxido sintase (PGHS), e também as melhores posições para a introdução de grupamentos químicos e modificações moleculares
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