5,818 research outputs found

    Targeted industry engagement was ‘spot-on’ for pasture dieback

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    Pasture Dieback (PD) is a condition that has been sporadically affecting sown pasture production in high rainfall zones of eastern Queensland for about 100 years. In recent years, there has been a large increase in the pasture species and area affected by PD. Affected pastures display progressive symptoms of stress which results in otherwise unexplained death, during what should be high growth periods. Currently, pathogenic organisms are the focus of multiple diagnostic research projects (Buck et. al 2021). Our objective was to increase graziers’ capability to accurately identify PD and implement appropriate management practices by conducting an industry engagement program

    alpha-nucleus potentials for the neutron-deficient p nuclei

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    alpha-nucleus potentials are one important ingredient for the understanding of the nucleosynthesis of heavy neutron-deficient p nuclei in the astrophysical gamma-process where these p nuclei are produced by a series of (gamma,n), (gamma,p), and (gamma,alpha) reactions. I present an improved alpha-nucleus potential at the astrophysically relevant sub-Coulomb energies which is derived from the analysis of alpha decay data and from a previously established systematic behavior of double-folding potentials.Comment: 6 pages, 3 figures, accepted for publication in Phys. Rev.

    Who wants to move? The role of neighbourhood change

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    This is the author accepted manuscript. The final version is available from SAGE via http://dx.doi.org/10.1177/0308518X15615367 There is growing interest in how, when and where neighbourhoods affect individual behaviours and outcomes. In Britain, falling levels of owner-occupation and the growth of ethnic minority populations have sparked a debate about how neighbourhood characteristics and neighbourhood change intersect with the decision to move. In this paper we investigate how mobility preferences vary with neighbourhood characteristics and neighbourhood change. We use multilevel logistic regression models to test whether this is configured by personal attributes or attachment to one's neighbourhood and perceived similarity to one's neighbours. The results show that neighbourhood deprivation, changes in neighbourhood ethnic composition and changes in tenure mix are associated with preferring to move. Importantly, we show that a feeling of belonging to the neighbourhood or feeling similar to others in the neighbourhood significantly reduces the desire to move. </jats:p

    A Multi-signal Variant for the GPU-based Parallelization of Growing Self-Organizing Networks

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    Among the many possible approaches for the parallelization of self-organizing networks, and in particular of growing self-organizing networks, perhaps the most common one is producing an optimized, parallel implementation of the standard sequential algorithms reported in the literature. In this paper we explore an alternative approach, based on a new algorithm variant specifically designed to match the features of the large-scale, fine-grained parallelism of GPUs, in which multiple input signals are processed at once. Comparative tests have been performed, using both parallel and sequential implementations of the new algorithm variant, in particular for a growing self-organizing network that reconstructs surfaces from point clouds. The experimental results show that this approach allows harnessing in a more effective way the intrinsic parallelism that the self-organizing networks algorithms seem intuitively to suggest, obtaining better performances even with networks of smaller size.Comment: 17 page

    Characterization of the binding and neutralizing properties of monoclonal antibodies against JCV

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    Antibody-based immunity to JC polyomavirus (JCV) is not well understood and monoclonal Antibodies (mAbs) that functionally neutralize the infectivity of JCV have not been documented. (1). Virus Like Particles (VLP)-based ELISAs can detect JCV-binding antibodies that do not necessarily neutralize the infectivity of JCV. Therefore, functional neutralization-based serology will be needed to validate candidate JCV VLP vaccines and therapeutic McAbs. (2). The neutralizing activity of McAbs can be specific for particular genotypes and clinical strains. Hence, VLPs from multiple genotypes may be needed to formulate a vaccine that could protect against diverse JCV strains circulating in patients with progressive multifocal encephalopathy (PML)

    Reliability Of A Novel Intracardiac Electrogram Method For AV And VV Delay Optimization And Comparability To Echocardiography Procedure For Determining Optimal Conduction Delays In CRT Patients

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    Background: Echocardiography is widely used to optimize CRT programming. A novel intracardiac electrogram method (IEGM) was recently developed as an automated programmer-based method, designed to calculate optimal atrioventricular (AV) and interventricular (VV) delays and provide optimized delay values as an alternative to standard echocardiographic assessment.Objective: This study was aimed at determining the reliability of this new method. Furthermore the comparability of IEGM to existing echocardiographic parameters for determining optimal conduction delays was verified.Methods: Eleven patients (age 62.9± 8.7; 81% male; 73% ischemic), previously implanted with a cardiac resynchronisation therapy defibrillator (CRT-D) underwent both echocardiographic and IEGM-based delay optimization.Results: Applying the IEGM method, concordance of three consecutively performed measurements was found in 3 (27%) patients for AV delay and in 5 (45%) patients for VV delay. Intra-individual variation between three measurements as assessed by the IEGM technique was up to 20 ms (AV: n=6; VV: n=4). E-wave, diastolic filling time and septal-to-lateral wall motion delay emerged as significantly different between the echo and IEGM optimization techniques (p < 0.05). The final AV delay setting was significantly different between both methods (echo: 126.4 ± 29.4 ms, IEGM: 183.6 ± 16.3 ms; p < 0.001; correlation: R = 0.573, p = 0.066). VV delay showed significant differences for optimized delays (echo: 46.4 ± 23.8 ms, IEGM: 10.9 ± 7.0 ms; p <0.01; correlation: R = -0.278, p = 0.407).Conclusion: The automated programmer-based IEGM-based method provides a simple and safe method to perform CRT optimization. However, the reliability of this method appears to be limited. Thus, it remains difficult for the examiner to determine the optimal hemodynamic settings. Additionally, as there was no correlation between the optimal AV- and VV-delays calculated by the IEGM method and the echo optimization, the use of the IEGM method and the comparability to the echo has not been definitely clarified

    Space construction system analysis. Part 2: Construction analysis

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    The construction methods specific to the end to end construction process for building the ETVP in low Earth orbit, using the space shuttle orbiter as a construction base, are analyzed. The analyses concerned three missions required to build the basic platform. The first mission involved performing the fabrication of beams in space and assembling the beams into a basic structural framework. The second mission was to install the forward support structure and aft support structure, the forward assembly, and a TT&C antenna. The third mission plan was to complete the construction of the platform and activate it to begin operations in low Earth orbit. The integration of the activities for each mission is described along with the construction requirements and construction logic

    The Ellipticity and Orientation of Clusters of Galaxies from N-Body Experiments

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    In this study we use simulations of 1283^3 particles to study the ellipticity and orientation of clusters of galaxies in N-body simulations of differing power-law initial spectra (P(k) \propto k^n ,n = +1, 0, -1, -2),anddensityparameters(), and density parameters (\Omega_0 = 0.2to1.0).Furthermore,unlikemosttheoreticalstudieswemimicmostobserversbyremovingallparticleswhichlieatdistancesgreaterthan21/hMpcfromtheclustercenterofmass.Wecomputedtheaxialratioandtheprincipalaxesusingtheinertiatensorofeachcluster.Themeanellipticityofclustersincreasesstronglywithincreasing to 1.0). Furthermore, unlike most theoretical studies we mimic most observers by removing all particles which lie at distances greater than 2 1/h Mpc from the cluster center of mass. We computed the axial ratio and the principal axes using the inertia tensor of each cluster. The mean ellipticity of clusters increases strongly with increasing n.Wealsofindthatclusterstendtobecomemoresphericalatsmallerradii.Wecomparedtheorientationofaclustertotheorientationofneighboringclustersasafunctionofdistance(correlation).Inaddition,weconsideredwhetheraclustersmajoraxistendstoliealongthelineconnectingittoaneighboringcluster,asafunctionofdistance(alignment).Bothalignmentsandcorrelationswerecomputedinthreedimensionsandinprojectiontomimicobservationalsurveys.Ourresultsshowthatsignificantalignmentsexistforallspectraatsmallseparations(. We also find that clusters tend to become more spherical at smaller radii. We compared the orientation of a cluster to the orientation of neighboring clusters as a function of distance (correlation). In addition, we considered whether a cluster's major axis tends to lie along the line connecting it to a neighboring cluster, as a function of distance (alignment). Both alignments and correlations were computed in three dimensions and in projection to mimic observational surveys. Our results show that significant alignments exist for all spectra at small separations (D < 15 h^{-1}Mpc)butdropsoffatlargerdistanceinastrongly Mpc) but drops off at larger distance in a strongly n-$dependent way.Comment: 22 pages, requires aaspp4.sty, flushrt.sty, and epsf.sty Revised manuscript, accepted for publication in Ap

    Does Migration Make You Happy?:A Longitudinal Study of Internal Migration and Subjective Well-Being

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    The authors acknowledge financial support from the Economic and Social Research Council (ESRC) (RES-625-28-0001). This project is part of the ESRC Centre for Population Change (CPC). Financial support from the Marie Curie programme under the European Union's Seventh Framework Programme (FP/2007-2013) / Career Integration Grant n. PCIG10-GA-2011-303728 (CIG Grant NBHCHOICE, Neighbourhood choice, neighbourhood sorting, and neighbourhood effects).The majority of quantitative studies on the consequences of internal migration focus almost exclusively on the labour-market outcomes and the material well-being of migrants. We investigate whether individuals who migrate within the UK become happier after the move than they were before, and whether the effect is permanent or transient. Using life-satisfaction responses from twelve waves of the British Household Panel Survey and employing a fixed-effects model, we derive a temporal pattern of migrants’ subjective well-being around the time of the migration event. Our findings make an original contribution by revealing that, on average, migration is preceded by a period when individuals experience a significant decline in happiness for a variety of reasons, including changes in personal living arrangements. Migration itself causes a boost in happiness, and brings people back to their initial levels. The research contributes, therefore, to advancing an understanding of migration in relation to set-point theory. Perhaps surprisingly, long-distance migrants are at least as happy as short-distance migrants despite the higher social and psychological costs involved. The findings of this paper add to the pressure to retheorize migration within a conceptual framework that accounts for social well-being from a life-course perspective.PostprintPeer reviewe
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