The Effects of Dietary Food Fortified with Vitamin B4 on Lipid Profiles in Serum and Liver Tissue

The effects of dietary food fortified with vitamin B4 on lipid profiles in serum and liver tissue were studied. Rats were paired-fed a 0.25% vitamin B4 diet or a diet without vitamin B4 for 10 days. Serum lipid levels were measured using enzyme assay kits. Lipids of liver tissues were extracted and the lipid contents were determined. A piece of liver was prepared to determine the activities of fatty acid synthase (FAS) and fatty acid β-oxidation. The results showed that animals fed a food fortified with vitamin B4 had higher level of serum TG, PL, total cholesterol, and high density lipoprotein. Their increases were approximately by 74%, 20%, 27%, and 27%, respectively. The significant changes in liver lipid were only found in PL component. This treatment promoted FAS activity, but impaired the fatty acid β-oxidation. In conclusion: Dietary food fortified with vitamin B4 induces hypertriglyceridemia and liver PL level

EFFECTS OF DIETARY ADENINE ON GROWTH, LIPID SECRETION, AND LIVER LIPID CONTENT

ABSTRACT The effects of dietary adenine on growth, lipid secretion, and liver lipid contents were studied. Rats were paired-fed 0.25 %adenine diet or a diet without adenine for 10 days. The final body weight and relative liver weight were recorded. Serum lipid profiles were measured using enzyme assay kits. Lipids of liver tissues were extracted and the lipid contents were determined. A peach of liver was prepared to determine the activities of fatty acid synthase (FAS) and fatty acid {3-oxidation.The results showed that animals fed an adenine diet reduced slightly body weight and relative liver weight and promoted serum triglyceride (TG), phospholipids (PL), total cholesterol, and high density lipoprotein concentrations. Their promotions were approximately by 74%, 20%, 27%, and 27%, respectively. The liver PL content increased significantly whereas the promotions of liver TG and cholesterol failed to reach significant level. Furthermore, the FAS activity slightly stimulated, but fatty acid {3-oxidation significantly decreased. In conclusion: dietary adenine suppressed slightly growth of body weight and relative liver weight but promoted secretion of lipid compounds from liver tissue into extra-hepaticand liver PL content. The enzyme activity of lipogenic was slightly stimulated whereas the lipolytic was significantly inhibited. Keywords: adenine, serum lipid, triglyceride, high density lipoprotein, cholestero

EDITORIAL: Vol. 5 No. 1, 2018

Jacson is one of journals published by JACSOnline Group Publisher (JACSOnline GP). Jacson is a scientific journal as a window of scholars from the field of Applied Chemical Science to disseminate their research works and opinion. The Jacson operates the non-profit work based on the rule according to the CC by NC SA 3.0.  Formerly Jacson is a Jacsonline (j-a-c-s-online)-Journal of Applied Chemical Science-online, however, since September 2016 the Jacsonline had moved to be a publisher and the remained journal of applied chemical science was stated to be named as a Jacson. Since there, the logo of the journal applied since 2012 was removed and its style partially changed. Because of these changes, there is shown differently in logo and style of articles between 2012 to 2015 and thereafter published. Moreover, during the periods up to 2015, the volume and the edition were not having a publishing fixed time. These facts were the first generation in Jacson management.                 The 2016 was the new stage of the Journal of Applied Chemical Science known as Jacson as mentioned above. There was not only changed in it brand style (logo) and separated its website from the publisher only but also the timing of the publishing was decided to perform which is December 14 and June 20. The December 14, 2016 was decided to start the first new version of the publishing processes with 5 articles. Once launching that new rule, the jacson publishes annually one volume with two editions. There is shown that volume 4, 2017 has two editions which are Vol. 4 No.1 and Vol. 4 No. 2, respectively. There were 6 articles for each edition of the Vol. 4 No.1 and Vol. 4 No. 2, respectively. This might be known as the six article rules. The six article rules were included the numbers of article published, reviewing process, included in digital object identifier (DOI), article charges system for open access, and ordering for the hard copy.                 All those changes within the six article rules applied above were for an adaptation of the JACSOnline GP with a new system as a member of the Publisher International Linking Association (PILA) under Crossref section. Since there, the JACSOnline GP ensures the articles published by the Jacson matched with the regulation encouraged by the PILA under the Crossref section. The DOI: 10.22341 is the unique identity of the JACSOnline GP among the publishers throughout the world.  Since Jacson’s articles have own DOI under the umbrella of JACSOnline GP, the articles disseminated by the Jacson are more visible. The articles published are now indexed in any international data bases such as Google Scholar, Crossref, Scilit, Chemical Abstract Service, and Copernicus. Since there, the Jacson as a scientific journal has been on its sit as one of the Scientific International Journals. Because of numbers and qualities of manuscripts entering the Jacson significantly increased, Vol. 5 No.1, numbers of articles disseminated by the Jacson increased which were 10 articles. Therefore, the rules of six articles are significantly moved into the 10 article rules

DIETARY ADENINE ALLEVIATES FATTY LIVER INDUCEDBY OROTICACID

ABSTRACT The effects of dietary adenine in fatty liver induced by orotic acid (OA) were studied. Rats were paired-fed 1% OA-supplemented diets with/or without 0.25% adenine or a diet without OA for 10 days. Serum lipid profiles were measured using enzyme assay kits. Lipids of liver tissues were extracted and liver lipid contents were determined.A peach of liver was prepared to determine the activities of fatty acid synthase (FAS) and fatty acid {3-oxidation.The results showed that liver TG content of OA-fed rats increased markedly in comparison to basal group. However, the addition of adenine to the diet reversed promotion of liver TG content to basal level. It was also found that FAS activities decreased. Furthermore, these diets reversed the inhibition of fatty acid {3-oxidationto basal level and induced the serum lipid levels secretion. Therefore, the alleviation of fatty liver in OA-treated rats given dietary adenine is associated with the inhibition of FAS activities accompanied with the promotion of mitochondrial fatty acid {3-oxidationand the promotion of serum lipid secretion from the hepatic tissue into the bloodstream. Keywords: adenine, orotic acid, serum lipid, triglyceride, fatty liver, hepatic steatosi

Performances of Zeolite, Coconut Shell, and Zeolite+Coconut Shell-Based Water Cartridges to Minimize Contaminants of Drinking Water

ABSTRACTS Performances of zeolite, coconut shell, and zeolite+coconut shell-based water cartridges to minimize contaminants of drinking waters wereconducted in the present study. The zeolite stones and coconut shell charcoal were powdered to be ≥ 60 meshes. The powders were packed intoa cartridge to provide zeolite, coconut shell, and zeolite+coconut shell (1:2) cartridges, respectively. Well waters allowed to flow through eachcartridge for a month. Thereafter, each water filtrate was harvested and analyzed numbers of parameters from four variables included in thequality table of drinking water. The total coliform found in each 100 mL of the well water equaled to 460 MPN (most possible number) whilethe fecal coli equaled to 150. When the well water flowed through the developing cartridges, the MPN content varied which depended on thecartridge materials qualitative compositions. Total coliform remained in water filtrates of the well waters flowed through the cartridges made ofzeolite, coconut charcoal, and their mixture (1:2 by volume) were 38, 240, and 96 MPN, respectively. These developed cartridges, therefore,could remove these total coliform from the well waters by 92, 48, and 79 %, respectively. Overall, the performance of the developed cartridgemade of zeolite was highest among those cartridges. Keywords: zeolite, water cartridge, coconut shell, coconut charcoal, zeolite cartridg

Dietary Food Fortified with Orotic Acid and Liver Function

The effects of dietary food fortified with orotic acid (1.0%) on liver function were studied in rats. The rats fed with orotic acid promoted liver triglyceride content markedly, that was 5-fold higher than that of the control. The liver malondialdehyde (MDA) content increased by 10%, but the gluthation peroxidase (GSH-Px) activity decreased by 50%. The serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities increased by 25% and 30%, respectively. Therefore, the decreased GSH-Px activity was associated with the promotions of AST, ALT, and the liver MDA levels. In conclusion: dietary orotic acid promotes lipid peroxidation but reduces the rate of the antioxidant enzyme. Therefore, dietary food fortified with orotic acid attenuates the liver function.&nbsp

The Effects of Dietary Food Fortified with Vitamin B4 on Lipid Profiles in Serum and Liver Tissue

The effects of dietary food fortified with vitamin B4 on lipid profiles in serum and liver tissue were studied. Rats were paired-fed a 0.25% vitamin B4 diet or a diet without vitamin B4 for 10 days. Serum lipid levels were measured using enzyme assay kits. Lipids of liver tissues were extracted and the lipid contents were determined. A piece of liver was prepared to determine the activities of fatty acid synthase (FAS) and fatty acid β-oxidation. The results showed that animals fed a food fortified with vitamin B4 had higher level of serum TG, PL, total cholesterol, and high density lipoprotein. Their increases were approximately by 74%, 20%, 27%, and 27%, respectively. The significant changes in liver lipid were only found in PL component. This treatment promoted FAS activity, but impaired the fatty acid β-oxidation. In conclusion: Dietary food fortified with vitamin B4 induces hypertriglyceridemia and liver PL level

DIETARY FOOD FORTIFIED WITH OROTIC ACID AND LIVER FUNCTION

The effects of dietary food fortified with orotic acid (1.0%) on liver function were studied in rats. The rats fed withorotic acid promoted liver triglyceride content markedly, that was 5-fold higher than that of the control. The livermalondialdehyde (MDA) content increased by 10%, but the gluthation peroxidase (GSH-Px) activity decreased by 50%.The serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities increased by 25% and 30%,respectively. Therefore, the decreased GSH-Px activity was associated with the promotions of AST, ALT, and the liverMDA levels. In conclusion: dietary orotic acid promotes lipid peroxidation but reduces the rate of the antioxidantenzyme. Therefore, dietary food fortified with orotic acid attenuates the liver function

EFFECTS OF DIETARY ADENINE ON GROWTH, LIPID SECRETION, AND LIVER LIPID CONTENT

The effects of dietary adenine on growth, lipid secretion, and liver lipid contents were studied. Rats were paired-fed 0.25 % adenine diet or a diet without adenine for 10 days. The final body weight and relative liver weight were recorded. Serum lipid profiles were measured using enzyme assay kits. Lipids of liver tissues were extracted and the lipid contents were determined. A peach of liver was prepared to determine the activities of fatty acid synthase (FAS) and fatty acid β-oxidation. The results showed that animals fed an adenine diet reduced slightly body weight and relative liver weight and promoted serum triglyceride (TG), phospholipids (PL), total cholesterol, and high density lipoprotein concentrations. Their promotions were approximately by 74%, 20%, 27%, and 27%, respectively. The liver PL content increased significantly whereas the promotions of liver TG and cholesterol failed to reach significant level. Furthermore, the FAS activity slightly stimulated, but fatty acid β-oxidation significantly decreased. In conclusion: dietary adenine suppressed slightly growth of body weight and relative liver weight but promoted secretion of lipid compounds from liver tissue into extra-hepatic and liver PL content. The enzyme activity of lipogenic was slightly stimulated whereas the lipolytic was significantly inhibited.   Keywords: adenine, serum lipid, triglyceride, high density lipoprotein, cholestero

The Effects of Dietary Food Fortified with Vitamin B4 on Lipid Profiles in Serum and Liver Tissue

The effects of dietary food fortified with vitamin B4 on lipid profiles in serum and liver tissue were studied. Rats were paired-fed a 0.25% vitamin B4 diet or a diet without vitamin B4 for 10 days. Serum lipid levels were measured using enzyme assay kits. Lipids of liver tissues were extracted and the lipid contents were determined. A piece of liver was prepared to determine the activities of fatty acid synthase (FAS) and fatty acid β-oxidation. The results showed that animals fed a food fortified with vitamin B4 had higher level of serum TG, PL, total cholesterol, and high density lipoprotein. Their increases were approximately by 74%, 20%, 27%, and 27%, respectively. The significant changes in liver lipid were only found in PL component. This treatment promoted FAS activity, but impaired the fatty acid β-oxidation. In conclusion: Dietary food fortified with vitamin B4 induces hypertriglyceridemia and liver PL level