4,354 research outputs found

    Achievable efficiencies for probabilistically cloning the states

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    We present an example of quantum computational tasks whose performance is enhanced if we distribute quantum information using quantum cloning. Furthermore we give achievable efficiencies for probabilistic cloning the quantum states used in implemented tasks for which cloning provides some enhancement in performance.Comment: 9 pages, 8 figure

    The Role of Solar Wind Hydrogen in Space Weathering: Insights from Laboratory-Irradiated Northwest Africa 12008

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    Micrometeoroid impacts, solar wind plasma interactions, and regolith gardening drive the complicated and nuanced mechanism of space weathering (or optical maturation); a process by which a materials optical properties are changed as a result of chemical and physical alterations at the surface of grains on airless bodies. Reddened slopes, attenuated absorption bands, and an overall reduction in albedo in the visible and near-IR wavelength ranges are primarily the result of native iron nanoparticle (npFe0) production within glassy rims that form from sputtering and vaporization. The sizes and abundance of these particles provide information about the relative surface exposure age of a particular grain. In addition, many studies have indicated that composition greatly affects the rate at which optical maturation occurs. Despite our understanding of how npFe0 affects optical signatures, the relative roles of micrometeoroid bombardment and solar wind interactions remains undetermined. To simulate the early effects of weathering by the solar wind and to determine thresholds for optical change with respect to a given mineral phase, we irradiated a fine-grained lunar basalt with 1 keV H+ to a fluence of 6.4 x 1016 H+ per sq.cm. Surface alterations within four phases have been evaluated using transmission electron microscopy (TEM). We found that for a given fluence of H+, the extent of damage acquired by each grain was dependent on its composition. No npFe(0) was produced in any of the phases evaluated in this study. These results are consistent with many previous studies conducted using ions of similar energy, but they also provide valuable information about the onset of space weathering and the role of the solar wind during the early stages of optical maturation

    Improved Charge Separation and Photovoltaic Performance of BiI3 Absorber Layers by Use of an In Situ Formed BiSI Interlayer

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    Stable and nontoxic bismuth iodide (BiI3) is emerging as a promising absorber material for solar cell applications as it possesses favorable optical properties such as a narrow bandgap (1.7 eV) and a high absorption coefficient (105 cm–1) in the visible region. Despite these promising features, solar cells employing this material have only achieved power conversion efficiencies in the region of 1% as of yet, which is distant from the theoretical efficiency limit of 28%. It is reasonable to suppose that the relatively low performance of BiI3-based solar cells may originate from very short carrier lifetimes (180–240 ps) in BiI3, which makes efficient separation of mobile charges a crucial factor for the improvement of the photovoltaic performance of this material. Herein, transient optical spectroscopy is employed to show that the use of a bismuth sulfide iodide interlayer between the electron transport layer (ETL) and the bismuth iodide absorber promotes efficient charge separation. On the basis of this knowledge, we report BiI3 solar cells with a power conversion efficiency of 1.21% using a solar cell architecture comprised of ITO/SnO2/BiSI/BiI3/organic HTM/Au

    Double In Situ Approach for the Preparation of Polymer Nanocomposite with Multi-functionality

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    A novel one-step synthetic route, the double in situ approach, is used to produce both TiO2nanoparticles and polymer (PET), and simultaneously forming a nanocomposite with multi-functionality. The method uses the release of water during esterification to hydrolyze titanium (IV) butoxide (Ti(OBu)4) forming nano-TiO2in the polymerization vessel. This new approach is of general significance in the preparation of polymer nanocomposites, and will lead to a new route in the synthesis of multi-functional polymer nanocomposites

    Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: Implication for breast cancer osteolytic bone metastases

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    Most breast cancer metastases in bone form osteolytic lesions, but the mechanisms of tumor-induced bone resorption and destruction are not fully understood. Although it is well recognized that Wnt/Β-catenin signaling is important for breast cancer tumorigenesis, the role of this pathway in breast cancer bone metastasis is unclear. Dickkopf1 (Dkk1) is a secreted Wnt/Β-catenin antagonist. In the present study, we demonstrated that activation of Wnt/Β-catenin signaling enhanced Dkk1 expression in breast cancer cells and that Dkk1 overexpression is a frequent event in breast cancer. We also found that human breast cancer cell lines that preferentially form osteolytic bone metastases exhibited increased levels of Wnt/Β-catenin signaling and Dkk1 expression. Moreover, we showed that breast cancer cell-produced Dkk1 blocked Wnt3A-induced osteoblastic differentiation and osteoprotegerin (OPG) expression of osteoblast precursor C2C12 cells and that these effects could be neutralized by a specific anti-Dkk1 antibody. In addition, we found that breast cancer cell conditioned media were able to block Wnt3A-induced NF-kappaB ligand reduction in C2C12 cells. Finally, we demonstrated that conditioned media from breast cancer cells in which Dkk1 expression had been silenced via RNAi were unable to block Wnt3A-induced C2C12 osteoblastic differentiation and OPG expression. Taken together, these results suggest that breast cancer-produced Dkk1 may be an important mechanistic link between primary breast tumors and secondary osteolytic bone metastases. © 2008 Wiley-Liss, Inc.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/60217/1/23625_ftp.pd

    Simulation-based analysis of micro-robots swimming at the center and near the wall of circular mini-channels

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    Swimming micro robots have great potential in biomedical applications such as targeted drug delivery, medical diagnosis, and destroying blood clots in arteries. Inspired by swimming micro organisms, micro robots can move in biofluids with helical tails attached to their bodies. In order to design and navigate micro robots, hydrodynamic characteristics of the flow field must be understood well. This work presents computational fluid dynamics (CFD) modeling and analysis of the flow due to the motion of micro robots that consist of magnetic heads and helical tails inside fluid-filled channels akin to bodily conduits; special emphasis is on the effects of the radial position of the robot. Time-averaged velocities, forces, torques, and efficiency of the micro robots placed in the channels are analyzed as functions of rotation frequency, helical pitch (wavelength) and helical radius (amplitude) of the tail. Results indicate that robots move faster and more efficiently near the wall than at the center of the channel. Forces acting on micro robots are asymmetrical due to the chirality of the robot’s tail and its motion. Moreover, robots placed near the wall have a different flow pattern around the head when compared to in-center and unbounded swimmers. According to simulation results, time-averaged for-ward velocity of the robot agrees well with the experimental values measured previously for a robot with almost the same dimensions

    The potential effects and use of Chinese herbal medicine pine pollen (Pinus Pollen) : a bibliometric analysis of pharmacological and clinical studies

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    Objective: To conduct a comprehensive literature search and bibliometric analysis to identify the breadth and volume of pharmacological and clinical studies on pine pollen (Pinus Pollen), and to identify the potential effects and use of pine pollen. Methods: Three Chinese electronic databases and two English electronic databases were searched for pharmacological and clinical studies on pine pollen. Data were extracted and analyzed and included: publication year, authors, study type, pharmacological research topics or clinical diseases/conditions, usage and type of preparation, authors’ conclusions and adverse effects. Results: Of 239 publications identified, 180 were pharmacological studies, 37 were clinical trials and 22 were reviews. Numbers of publications increased particularly from 2004 onwards. The top 10 most frequent topics in pharmacological studies were immune regulation, anti-senility, anti-oxidation, liver protection, inhibiting prostate hyperplasia, inhibiting tumor cell proliferation, lowering blood glucose, lowering blood lipids, anti-fatigue, and improving intestinal function. The top 10 most frequent clinical diseases treated or where pine pollen was used as an adjuvant were bedsores, diaper dermatitis, hyperlipidemia, oral mucositis, eczema, hyperplasia of prostate, hypertension, prostatitis, type 2 diabetes mellitus, and radiodermatitis. Eight trials reported no adverse events associated with pine pollen, one reported mild gastrointestinal reactions but symptoms disappeared without special management. Conclusion: There have been an increasing number of publications on pine pollen during the past 20 years. Pharmacological studies have shown many potential benefits and clinical studies have indicated some positive effects when it is either used as a single herb or as an adjuvant to treat disease. Its use as a topical agent especially for skin diseases was notable
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