Management's cargo handling problems in the domestic shipping industry

Thesis (M.B.A.)--Boston Universit

Media Production and disruptive innovation: exploring the interrelations between children, tablets, teachers and texts in subject English settings

This article concerns Key Stage 3 boys’ and student teachers’ responses to literature through the production of moving image, sound and photography in a formal context. The researchers’ interests centre on media making with iPads and the ways in which young people articulate textual understanding through production. Under the guidance of their tutors, PGCE students and pupils engage with digital tools to explore new forms of cultural expression, inviting creative practice and critical thinking. The article incorporates multiple perspectives from: the children, the student teachers, the English and Drama teachers, the teacher trainers / lecturers in English and Drama, and a doctoral researcher interested in the distinctive nature of making with digital media and associated ontological issues. A sociocultural overview contextualises the study before an exploration of the ways in which pedagogies and epistemological understandings, often associated with non-formal media making, constructively challenge traditional Secondary English classroom practices

Social and Technological Innovation in Teaching Public Affairs: Introduction to the Symposium

Technology can be defined as “the social, material, or cloud/cyberspace tools used to manipulate human behavior to achieve a specified objective.” In the classroom, teachers use a variety of technologies to elicit desired student response or output and ultimately to achieve a level of learning appropriate for particular students. For example, decisions to use a chalk/white board versus PowerPoint during a lecture are often made based on the nature of engagement desired with the students. Arranging seats or desks in a classroom in a lecture format, an open circle, or an open square generates different types of engagement among and with students. Social media and networking tools enable relationships to develop that may not have been possible in a strictly face-to-face environment, particularly within the time constraints of a typical class period

Stroke outcomes in a socio-economically disadvantaged urban community

Aims. To determine survival, disability and functional outcomes of stroke patients following their discharge from an acute stroke unit in an urban community with limited rehabilitative resources. Methods. Stroke patients were recruited from a district hospital in Cape Town and followed-up for 6 months. Clinical characteristics, demographic and socioeconomic data, and disability and function as measured by modified Rankin Score (mRS), modified Barthel Index (mBI) at recruitment and 3 follow-up visits, were recorded. Results. The study included 196 patients. Median age was 60 (IQR 51 - 69) years, 135 (68.9%) were female, 57.7% black, 42.3% coloured, and 45 (23%) died within 6 months. At discharge, median mBI score was 7 (IQR 3 - 12) and median mRS 4 (IQR 3 - 5). In the multivariate regression models, only function (mBI OR 0.88, 95% confidence interval (CI) 0.79 - 0.96, p<0.0001) and disability (mRS 0R 2.34, 95%CI 1.20 - 4.54, p<0.0001) were independently associated with risk of death. Shack housing was independently associated with moderate or severe disability (odds ratio 3.42, 95%CI 1.22 - 9.59, p=0.02). Despite limited rehabilitation resources, 67% of survivors had mild to moderate disability at 6 months. Conclusion. Apart from initial stroke severity, risk factors for poor survival were a severe disability category and the presence of impaired swallowing at discharge. Shack housing was independently associated with poor functional outcomes. These findings should be helpful in allocating home-based care and inpatient rehabilitation resources to high-risk groups to improve outcomes

Registration of amiloride in South Africa: Cutting the Gordian knot

Amiloride is an antagonist of the renal tubular epithelial sodium channel (ENaC). As such, it is a diuretic that is both potassium and magnesium sparing. It is used for the treatment of potassium depletion and hypertension, and is the specific therapy for hypertension due to overactivity of the ENaC (Liddle syndrome and several additional genetic causes of the Liddle phenotype - low renin and low aldosterone). It is listed as a World Health Organization essential drug, but has never been registered in South Africa (SA) and can therefore only be prescribed under a Section 21 application to the SA Health Products Regulatory Authority (SAHPRA) on a case-by-case basis. In SA, \u3e50% of patients treated for hypertension are not controlled. In the USA, the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study reported that African Americans are more likely to be diagnosed with hypertension, more likely to be treated, more likely to be treated intensively, and less likely to achieve blood pressure (BP) control. Although the reasons are complex, studies show that 10 - 20% of blacks may carry the Liddle phenotype. Observational data and a controlled clinical trial done in three African countries have shown that these patients respond to amiloride and not to conventional guideline-based antihypertensive treatment. The former is likely to result in a significant reduction in cardiovascular, stroke and kidney morbidity and mortality, because of improved BP control. Amiloride is very unlikely to ever be registered in SA, as it was first developed \u3e50 years ago, and SAHPRA regulations prevent widespread prescription of this essential drug. This is a classic Gordian knot that requires a novel approach from authorities to sever the knot and improve the health of many South Africans

Immobilization of the Erupting Molar in the Syrian Hamster

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/67148/2/10.1177_00220345650440061901.pd

Inherited polyglutamine spinocerebellar ataxias in South Africa

Objective. To determine the frequency and distribution of polyglutamine spinocerebellar ataxias (SCAs) from referrals over a 24-year period to the National Health Laboratory Service (NHLS) in South Africa (SA). Methods. Paper-based clinical reports in the University of Cape Town laboratory and the NHLS electronic patient record database spanning a 24-year period were mined for information regarding the molecular diagnosis, ethnicity and CAG repeat length for individuals referred for molecular genetic testing for the polyglutamine SCAs. Results. SCA1 and 7 are the most frequent types of polyglutamine SCA in the SA patient population, followed by SCA2, 3 and 6. SCA1 is the most common type in the coloured, white and Indian populations, whereas the majority of indigenous black African patients are affected with SCA7 and 2. Of individuals tested, 22% were found to be positive for one of the polyglutamine SCAs. Conclusion. Although trends in the frequency and distribution of the polyglutamine SCAs in SA have not changed significantly since our previous study in 2003, they differ remarkably from those reported elsewhere, and reflect the unique genetic and demographic background of SA. The provision of accurate and complete patient information and family history is crucial to the diagnostic process, to enable comprehensive epidemiological studies and assist in developing therapeutic and patient management strategies