Evidence Report: Risk of Spaceflight Associated Neuro-ocular Syndrome (SANS)

A subset of astronauts develop neuro-ocular structural and functional changes during prolonged periods of spaceflight that may lead to additional neurologic and ocular consequences upon return to Earth

Operational Transition from the First-Generation Heidelberg Spectralis Optical Coherence Tomography [OCT("OCT1")] to the Second-Generation Heidelberg Spectralis OCT("OCT2")

The Heidelberg Spectralis "OCT2", which recently became commercially available, is going to be implemented at the Johnson Space Center Flight Medicine Clinic and on board the International Space Station. Due to the increased scan rate of the "OCT2", this upgrade will allow for significant reduction in valuable crew testing time and also allow for additional capabilities, like OCT Angiography and Multi-Color Fundus Imaging. Due to the custom scans used to monitor Space Flight-Associated Neuro-ocular Syndrome (SANS) in our crewmembers, an evaluation to assess the impacts of transitioning from "OCT1" to "OCT2" was performed. An engineering assessment (N=1) was performed to identify any potential impacts of maintaining an "OCT1" on board ISS while implementing an "OCT2" in the JSC Clinic. "OCT2" implementation will lag JSC FMC clinical implementation due to the flight certification/manifestation process. The clinical assessment was performed (n=12) to identify any impacts due to the replacement of the "OCT1" with the "OCT2" to the longitudinal OCT data across a crewmember's mission/lifetime. The qualitative results from the engineering and clinical evaluation will be reported, as well as the quantitative assessment of the clinical variable

Drones, Morality, and Vulnerability: Two Arguments Against Automated Killing

This chapter articulates and discusses several arguments against the lethal use of unmanned aerial vehicles, often called drones. A distinction is made between targeted killing, killing at a distance, and automated killing, which is used to map the arguments against lethal drones. After considering issues concerning the justification of war, the argument that targeted killing makes it easier to start a war, and the argument that killing at a distance is problematic, this chapter focuses on two arguments against automated killing, which are relevant to all kinds of “machine killing”. The first argument (from moral agency) questions if machines can ever be moral agents and is based on differences in capacities for moral decision-making between humans and machines. The second argument (from moral patiency), which has received far less attention in the literature on machine ethics and ethics of drones, focuses on the question if machines can ever be “moral patients”. It is argued that there is a morally significant qualitative difference in vulnerability and way of being between drones and humans, and that because of this asymmetry fully automated killing without or with little human involvement is not justified

Immune system dysregulation preceding a case of laboratory-confirmed zoster/dermatitis on board the International Space Station

A case report detailing, for the first time, a case of laboratory-confirmed zoster in an astronaut on board the International Space Station is presented. The findings of reduced T-cell function, cytokine imbalance, and increased stress hormones which preceded the event are detailed. Relevance for deep space countermeasures is discussed

Globalization, security and drones

No abstract availabl

Casas, Bartolomé de Las (Seville 1484–Madrid 1566)

Las Casa

Las Casas, Bartolomé de

Bartolome de Las Casas's contribution to political and legal philosophy