4,757 research outputs found

    Ausgestaltung von Management by Objectives innerhalb von Leistungslohnsystemen: Unterschiede in der Motivation zwischen Mitarbeitenden und Managern

    Full text link
    Management by Objectives (MbO) wird definiert als Synthese von Zielsetzung, Partizipation bei Zielvereinbarungen und Feedback über die Zielerreichung. Dieser Beitrag untersucht, wie sich die Ausgestaltung von MbO innerhalb von Leistungsvergütungssystemen auf die Motivation von Mitarbeitenden und Vorgesetzten auswirkt. Als Datenbasis dient eine Stichprobe von 342 Unternehmen in der Schweiz. Die Untersuchungsergebnisse zeigen, dass 96% der betrachteten Leistungslohngruppen Management by Objectives anwenden. Bei 83% ist die Leistungsvergütung direkt mit dem MbO-System verknüpft. Eine detaillierte Betrachtung zeigt, dass die Ausgestaltung der einzelnen Elemente von MbO – Zielsetzung, Partizipation und Feedback – je nach Hierarchiestufe verschiedene Bedeutungen haben. Während für die Mitarbeitenden ohne Führungsfunktion in erster Linie die Kommunikation über die Zielerreichung einen positiven Einfluss auf die Motivation hat, ist für das Management die Qualität der Zielsetzungen zentral

    Fundamental Framework for Task Mining Technology Adoption: Results from a Qualitative Empirical Study

    Get PDF
    Digitalization influences business processes and their management. Digital technologies such as Process Mining (PM) or Robotic Process Automation (RPA), which are becoming more and more prevalent, offer new possibilities for process analysis, monitoring, and automation. PM can further be helpful in identifying processes that are suitable for RPA. However, purely applying PM at the business data level often does not produce all the details required to assess RPA suitability. These necessary details can be supplemented by Task Mining (TM), a technology that can analyze tasks at a desktop data level, which opens further potential beyond the automation benefits. However, the currently available scientific literature on TM is scarce and empirical qualitative studies or case studies on the adoption of TM technology from a BPM perspective are missing. Therefore, this paper develops a fundamental framework for TM technology adoption based on a qualitative empirical study involving experts via semi-structured interviews, which are analyzed according to the qualitative content analysis based on the methodology of Mayring. The framework relates five potential benefits, two opportunities, four risks, and four basic requirements identified from the qualitative study. It thus provides a new valid starting point for future research efforts and serves as a guideline for managers in practice to evaluate a potential TM deployment in the company

    Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts

    No full text
    A comprehensive characterization of the lipidome from limited starting material remains very challenging. Here we report a high-sensitivity lipidomics workflow based on nanoflow liquid chromatography and trapped ion mobility spectrometry (TIMS). Taking advantage of parallel accumulation-serial fragmentation (PASEF), we fragment on average 15 precursors in each of 100 ms TIMS scans, while maintaining the full mobility resolution of co-eluting isomers. The acquisition speed of over 100 Hz allows us to obtain MS/MS spectra of the vast majority of isotope patterns. Analyzing 1 mu L of human plasma, PASEF increases the number of identified lipids more than three times over standard TIMS-MS/MS, achieving attomole sensitivity. Building on high intra- and inter-laboratory precision and accuracy of TIMS collisional cross sections (CCS), we compile 1856 lipid CCS values from plasma, liver and cancer cells. Our study establishes PASEF in lipid analysis and paves the way for sensitive, ion mobility-enhanced lipidomics in four dimensions

    Measuring the equation of state of a hard-disc fluid

    Full text link
    We use video microscopy to study a two-dimensional (2D) model fluid of charged colloidal particles suspended in water and compute the pressure from the measured particle configurations. Direct experimental control over the particle density by means of optical tweezers allows the precise measurement of pressure as a function of density. We compare our data with theoretical predictions for the equation of state, the pair-correlation function and the compressibility of a hard-disc fluid and find good agreement, both for the fluid and the solid phase. In particular the location of the transition point agrees well with results from Monte Carlo simulations.Comment: 7 pages, to appear in EPL, slightly corrected versio

    The Evolution of the Global Star Formation History as Measured from the Hubble Deep Field

    Full text link
    The Hubble Deep Field (HDF) is the deepest set of multicolor optical photometric observations ever undertaken, and offers a valuable data set with which to study galaxy evolution. Combining the optical WFPC2 data with ground-based near-infrared photometry, we derive photometrically estimated redshifts for HDF galaxies with J<23.5. We demonstrate that incorporating the near-infrared data reduces the uncertainty in the estimated redshifts by approximately 40% and is required to remove systematic uncertainties within the redshift range 1<z<2. Utilizing these photometric redshifts, we determine the evolution of the comoving ultraviolet (2800 A) luminosity density (presumed to be proportional to the global star formation rate) from a redshift of z=0.5 to z=2. We find that the global star formation rate increases rapidly with redshift, rising by a factor of 12 from a redshift of zero to a peak at z~1.5. For redshifts beyond 1.5, it decreases monotonically. Our measures of the star formation rate are consistent with those found by Lilly et al. (1996) from the CFRS at z 2, and bridge the redshift gap between those two samples. The overall star formation or metal enrichment rate history is consistent with the predictions of Pei and Fall (1995) based on the evolving HI content of Lyman-alpha QSO absorption line systems.Comment: Latex format, 10 pages, 3 postscript figures. Accepted for publication in Ap J Letter

    The Sec61p Complex Mediates the Integration of a Membrane Protein by Allowing Lipid Partitioning of the Transmembrane Domain

    Get PDF
    AbstractWe have investigated how the transmembrane (TM) domain of a membrane protein is cotranslationally integrated into the endoplasmic reticulum. We demonstrate that the Sec61p channel allows the TM domain to bypass the barrier posed by the polar head groups of the lipid bilayer and come into contact with the hydrophobic interior of the membrane. Together with the TRAM protein, Sec61p provides a site in the membrane, at the interface of channel and lipid, through which a TM domain can dynamically equilibrate between the lipid and aqueous phases, depending on the hydrophobicity of the TM domain and the length of the polypeptide segment tethering it to the ribosome. Our results suggest a unifying, lipid-partitioning model which can explain the general behavior of hydrophobic topogenic sequences
    corecore