203 research outputs found
Post-Newtonian Lagrangian planetary equations
We present a method to study the time variation of the orbital parameters of
a Post-Keplerian binary system undergoing a generic external perturbation. The
method is the relativistic extension of the planetary Lagrangian equations. The
theory only assumes the smallness of the external perturbation while
relativistic effects are already included in the unperturbed problem. This is
the major advantage of this novel approach over classical Lagrangian methods.Comment: 8 pages; revtex; accepted for publication in Phys. Rev.
A protocol for high-frequency oscillatory ventilation in adults: Results from a roundtable discussion*
Fourier Acceleration of Langevin Molecular Dynamics
Fourier acceleration has been successfully applied to the simulation of
lattice field theories for more than a decade. In this paper, we extend the
method to the dynamics of discrete particles moving in continuum. Although our
method is based on a mapping of the particles' dynamics to a regular grid so
that discrete Fourier transforms may be taken, it should be emphasized that the
introduction of the grid is a purely algorithmic device and that no smoothing,
coarse-graining or mean-field approximations are made. The method thus can be
applied to the equations of motion of molecular dynamics (MD), or its Langevin
or Brownian variants. For example, in Langevin MD simulations our acceleration
technique permits a straightforward spectral decomposition of forces so that
the long-wavelength modes are integrated with a longer time step, thereby
reducing the time required to reach equilibrium or to decorrelate the system in
equilibrium. Speedup factors of up to 30 are observed relative to pure
(unaccelerated) Langevin MD. As with acceleration of critical lattice models,
even further gains relative to the unaccelerated method are expected for larger
systems. Preliminary results for Fourier-accelerated molecular dynamics are
presented in order to illustrate the basic concepts. Possible extensions of the
method and further lines of research are discussed.Comment: 11 pages, two illustrations included using graphic
Lung protective mechanical ventilation and two year survival in patients with acute lung injury: prospective cohort study
Objective To evaluate the association of volume limited and pressure limited (lung protective) mechanical ventilation with two year survival in patients with acute lung injury
Early High-Dose Vitamin D3 for Critically Ill, Vitamin D-Deficient Patients
BACKGROUND: Vitamin D deficiency is a common, potentially reversible contributor to morbidity and mortality among critically ill patients. The potential benefits of vitamin D supplementation in acute critical illness require further study.
METHODS: We conducted a randomized, double-blind, placebo-controlled, phase 3 trial of early vitamin D3 supplementation in critically ill, vitamin D-deficient patients who were at high risk for death. Randomization occurred within 12 hours after the decision to admit the patient to an intensive care unit. Eligible patients received a single enteral dose of 540,000 IU of vitamin D3 or matched placebo. The primary end point was 90-day all-cause, all-location mortality.
RESULTS: A total of 1360 patients were found to be vitamin D-deficient during point-of-care screening and underwent randomization. Of these patients, 1078 had baseline vitamin D deficiency (25-hydroxyvitamin D level,[50 nmol per liter]) confirmed by subsequent testing and were included in the primary analysis population. The mean day 3 level of 25-hydroxyvitamin D was 46.9±23.2 ng per milliliter (117±58 nmol per liter) in the vitamin D group and 11.4±5.6 ng per milliliter (28±14 nmol per liter) in the placebo group (difference, 35.5 ng per milliliter; 95% confidence interval [CI], 31.5 to 39.6). The 90-day mortality was 23.5% in the vitamin D group (125 of 531 patients) and 20.6% in the placebo group (109 of 528 patients) (difference, 2.9 percentage points; 95% CI, -2.1 to 7.9; P = 0.26). There were no clinically important differences between the groups with respect to secondary clinical, physiological, or safety end points. The severity of vitamin D deficiency at baseline did not affect the association between the treatment assignment and mortality.
CONCLUSIONS: Early administration of high-dose enteral vitamin D3 did not provide an advantage over placebo with respect to 90-day mortality or other, nonfatal outcomes among critically ill, vitamin D-deficient patients.
METHODS: We conducted a randomized, double-blind, placebo-controlled, phase 3 trial of early vitamin D3 supplementation in critically ill, vitamin D-deficient patients who were at high risk for death. Randomization occurred within 12 hours after the decision to admit the patient to an intensive care unit. Eligible patients received a single enteral dose of 540,000 IU of vitamin D3 or matched placebo. The primary end point was 90-day all-cause, all-location mortality
Measurement of the Branching Ratios for the Decays of , and
Using a data sample with integrated luminosity of about 3.9 fb^{-1} collected
in e+ e- annihilation with the CLEO-II detector at the Cornell Electron Storage
Ring, we have measured the branching ratios for the decay modes Ds -> (eta,
eta') pi and Ds -> (eta, eta') rho relative to Ds -> phi pi. These decay modes
are among the most common hadronic decays of the Ds's and can be related by
factorization to the semileptonic decays Ds -> (eta,eta') l nu. The results
obtained are compared with previous CLEO results and with the branching ratios
measured for the related semileptonic decays. We also report results on the
Cabibbo-suppressed decays of the D+ to the same final states.Comment: 18 page postscript file, postscript file also available through
http://w4.lns.cornell.edu/public/CLN
Measurement of the Inclusive Semi-electronic Branching Fraction
Using the angular correlation between the emitted in a decay and the emitted in the subsequent decay, we have measured the branching fraction for the
inclusive semi-electronic decay of the meson to be: {\cal B}(D^0
\rightarrow X e^+ \nu) = [6.64 \pm 0.18 (stat.) \pm 0.29 (syst.)] \%. The
result is based on 1.7 fb of collisions recorded by the CLEO II
detector located at the Cornell Electron Storage Ring (CESR). Combining the
analysis presented in this paper with previous CLEO results we find,
\frac{{\cal B} (D^0 \rightarrow X e^+ \nu)}
{{\cal B} (D^0 \rightarrow K^- \pi^+)}
= 1.684 \pm 0.056 (stat.) \pm 0.093(syst.) and
\frac{{\cal B}(D\rightarrow K^-e^+\nu)}
{{\cal B}(D\rightarrow Xe^+\nu)}
= 0.581 \pm 0.023 (stat.) \pm 0.028(syst.).
The difference between the inclusive rate and the sum of the measured
exclusive branching fractions (measured at CLEO and other experiments) is of the inclusive rate.Comment: Latex file, 33pages, 4 figures Submitted to PR
Limit on the Two-Photon Production of the Glueball Candidate at CLEO
We use the CLEO detector at the Cornell electron-positron storage ring, CESR,
to search for the two-photon production of the glueball candidate f_J(2220) in
its decay to K_s K_s. We present a restrictive upper limit on the product of
the two-photon partial width and the K_s K_s branching fraction. We use this
limit to calculate a lower limit on the stickiness, which is a measure of the
two-gluon coupling relative to the two-photon coupling. This limit on
stickiness indicates that the f_J(2220) has substantial glueball content.Comment: 9 page postscript file, postscript file also available through
http://w4.lns.cornell.edu/public/CLN
Determination of the Michel Parameters and the tau Neutrino Helicity in tau Decay
Using the CLEO II detector at the storage ring CESR, we have
determined the Michel parameters , , and in decay as well as the tau neutrino helicity parameter
in decay. From a data sample of
tau pairs produced at , using events of
the topology and , and the determined sign of , the combined
result of the three samples is: , , , and
. The results are in agreement with
the Standard Model V-A interaction.Comment: 18 page postscript file, postscript file also available through
http://w4.lns.cornell.edu/public/CLN
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