442 research outputs found
From Service to Experience: Understanding and Defining the Hospitality Business
Failure adequately to define or understand hospitality as a commercial phenomenon has created a fragmented academic environment and a schizophrenia in the industry that has the potential to limit its development as a global industry. This article suggests that, by redefining hospitality as behaviour and experience, a new perspective emerges that has exciting implications for the management of hospitality businesses. A framework to describe hospitality in the commercial domain is proposed. This framework suggests a focus on the host–guest relationship, generosity, theatre and performance, ‘lots of little surprises’, and the security of strangers – a focus that provides guests with experiences that are personal, memorable and add value to their lives
Associated Absorption Lines in the Radio-Loud Quasar 3C 351: Far-Ultraviolet Echelle Spectroscopy from the Hubble Space Telescope
As one of the most luminous radio-loud quasars showing intrinsic ultraviolet
(UV) and X-ray absorption, 3C 351 provides a laboratory for studying the
kinematics and physical conditions of such ionized absorbers. We present an
analysis of the intrinsic absorption lines in the high-resolution ( 7
km/s) far-UV spectrum which was obtained from observations with the Space
Telescope Imaging Spectrograph (STIS) on board the Hubble Space Telescope
(HST). The spectrum spans wavelengths from 1150 \AA to 1710 \AA, and shows
strong emission lines from O VI and Ly. Associated absorption lines are
present on the blue wings of the high-ionization emission doublets O VI
1032,1038 and N V 1238,1242, as well as the
Lyman lines through Ly. These intrinsic absorption features are
resolved into several distinct kinematic components, covering rest-frame
velocities from -40 to -2800 km/s, with respect to the systemic redshift of
. For the majority of these absorption line regions, strong
evidence of partial covering of both the background continuum source and the
BELR is found, which supports the intrinsic absorption origin and rules out the
possibility that the absorption arises in some associated cluster of galaxies.
The relationship between the far-UV absorbers and X-ray `warm' absorbers are
studied with the assistance of photoionization models. Most of the UV
associated absorption components have low values of the ionization parameter
and total hydrogen column densities, which is inconsistent with previous claims
that the UV and X-ray absorption arises in the same material. Analysis of these
components supports a picture with a wide range of ionization parameters,
temperatures, and column densities in AGN outflows.Comment: 27 pages with 5 figures, accepted by Ap
The Intrinsic Absorber in QSO 2359-1241: Keck and HST Observations
We present detailed analyses of the absorption spectrum seen in QSO 2359-1241
(NVSS J235953-124148). Keck HIRES data reveal absorption from twenty
transitions arising from: He I, Mg I, Mg II, Ca II, and Fe II. HST data show
broad absorption lines (BALs) from Al III 1857, C IV 1549, Si IV 1397, and N V
1240. Absorption from excited Fe II states constrains the temperature of the
absorber to 2000K < T < 10,000K and puts a lower limit of 10^5 cm^{-3} on the
electron number density. Saturation diagnostics show that the real column
densities of He I and Fe II can be determined, allowing to derive meaningful
constraints on the ionization equilibrium and abundances in the flow. The
ionization parameter is constrained by the iron, helium and magnesium data to
-3.0 < log(U) < -2.5 and the observed column densities can be reproduced
without assuming departure from solar abundances. From comparison of the He I
and Fe II absorption features we infer that the outflow seen in QSO 2359-1241
is not shielded by a hydrogen ionization front and therefore that the existence
of low-ionization species in the outflow (e.g., Mg II, Al III, Fe II) does not
necessitate the existence of such a front. We find that the velocity width of
the absorption systematically increases as a function of ionization and to a
lesser extent with abundance. Complementary analyses of the radio and
polarization properties of the object are discussed in a companion paper
(Brotherton et al. 2000).Comment: 30 pages, 9 figures, in press with the Ap
The FIRST Bright Quasar Survey. II. 60 Nights and 1200 Spectra Later
We have used the VLA FIRST survey and the APM catalog of the POSS-I plates as
the basis for constructing a new radio-selected sample of optically bright
quasars. This is the first radio-selected sample that is competitive in size
with current optically selected quasar surveys. Using only two basic criteria,
radio-optical positional coincidence and optical morphology, quasars and BL
Lacs can be identified with 60% selection efficiency; the efficiency increases
to 70% for objects fainter than magnitude 17. We show that a more sophisticated
selection scheme can predict with better than 85% reliability which candidates
will turn out to be quasars.
This paper presents the second installment of the FIRST Bright Quasar Survey
with a catalog of 636 quasars distributed over 2682 square degrees. The quasar
sample is characterized and all spectra are displayed. The FBQS detects both
radio-loud and radio-quiet quasars out to a redshift z>3. We find a large
population of objects of intermediate radio-loudness; there is no evidence in
our sample for a bimodal distribution of radio characteristics. The sample
includes ~29 broad absorption line quasars, both high and low ionization, and a
number of new objects with remarkable optical spectra.Comment: 41 pages plus 39 gifs which contain all quasar spectra. Accepted for
publication in the Astrophysical Journal Supplement Serie
Reduction of low- and high-grade cervical abnormalities associated with high uptake of the HPV bivalent vaccine in Scotland
In Scotland, a national HPV immunisation programme began in 2008 for 12-13 year olds, with a catch-up campaign from 2008-2011 for those under the age of 18. To monitor the impact of HPV immunisation on cervical disease at the population level, a programme of national surveillance was established. We analysed colposcopy data from a cohort of women born between 1988-1992 who entered the Scottish Cervical Screening Programme (SCSP) and were aged 20-21 in 2008-2012. By linking datasets from the SCSP and colposcopy services, we observed a significant reduction in diagnoses of cervical intraepithelial neoplasia 1 (CIN 1) (RR 0.71, 95% CI 0.58 to 0.87, p=0.0008), CIN 2 (RR 0.5, 95% CI 0.4, 0.63, p<0.0001) and CIN 3 (RR 0.45, 95% CI 0.35 to 0.58, p< 0.0001) for women who received 3 doses of vaccine compared with unvaccinated women. To our knowledge, this is one of the first studies to show a reduction of low and high grade cervical intraepithelial neoplasia associated with high uptake of the HPV bivalent vaccine at the population level. These data are very encouraging for countries that have achieved high HPV vaccine uptake
Radio-optical scrutiny of compact AGN: Correlations between properties of pc-scale jets and optical nuclear emission
We study the correlations between the Very Long Baseline Array radio emission
at 15 GHz, extended emission at 151 MHz, and optical nuclear emission at 5100
AA for a complete sample of 135 compact jets. We use the partial Kendall's tau
correlation analysis to check the link between radio properties of parsec-scale
jets and optical luminosities of host AGN. We find a significant positive
correlation for 99 quasars between optical nuclear luminosities and total radio
(VLBA) luminosities of unresolved cores at 15 GHz originated at milliarcseconds
scales. For 18 BL Lacs, the optical continuum emission correlates with the
radio emission of the jet at 15 GHz. We suggest that the radio and optical
emission are beamed and originate in the innermost part of the
sub--parsec-scale jet in quasars. Analysis of the relation between the apparent
speed of the jet and the optical nuclear luminosity at 5100 AA supports the
relativistic beaming model for the optical emission generated in the jet, and
allows the peak values of the intrinsic optical luminosity of the jet and its
Lorentz factor to be estimated for the populations of quasars, BL Lacs, and
radio galaxies. The radio-loudness of quasars is found to increase at high
redshifts, which can be a result of lower efficiency of the accretion in AGN
having higher radio luminosities. A strong positive correlation is found
between the intrinsic kinetic power of the jet and the apparent luminosities of
the total and the unresolved core emission of the jet at 15 GHz. This
correlation is interpreted in terms of intrinsically more luminous parsec-scale
jet producing more luminous extended structure which is detectable at low radio
frequencies, 151 MHz. A possibility that the low frequency radio emission is
relativistically beamed in superluminal AGN and therefore correlates with radio
luminosity of the jet at 15 GHz can not be ruled out (abridged).Comment: 16 pages, 10 figuers; minor comments are added; accepted to A&
Macrocyclic colibactin induces DNA double-strand breaks via copper-mediated oxidative cleavage.
Colibactin is an assumed human gut bacterial genotoxin, whose biosynthesis is linked to the clb genomic island that has a widespread distribution in pathogenic and commensal human enterobacteria. Colibactin-producing gut microbes promote colon tumour formation and enhance the progression of colorectal cancer via cellular senescence and death induced by DNA double-strand breaks (DSBs); however, the chemical basis that contributes to the pathogenesis at the molecular level has not been fully characterized. Here, we report the discovery of colibactin-645, a macrocyclic colibactin metabolite that recapitulates the previously assumed genotoxicity and cytotoxicity. Colibactin-645 shows strong DNA DSB activity in vitro and in human cell cultures via a unique copper-mediated oxidative mechanism. We also delineate a complete biosynthetic model for colibactin-645, which highlights a unique fate of the aminomalonate-building monomer in forming the C-terminal 5-hydroxy-4-oxazolecarboxylic acid moiety through the activities of both the polyketide synthase ClbO and the amidase ClbL. This work thus provides a molecular basis for colibactin's DNA DSB activity and facilitates further mechanistic study of colibactin-related colorectal cancer incidence and prevention
Extreme Starbursts in the Local Universe
The "Extreme starbursts in the local universe" workshop was held at the
Insituto de Astrofisica de Andalucia in Granada, Spain on 21-25 June 2010.
Bearing in mind the advent of a new generation of facilities such as JWST,
Herschel, ALMA, eVLA and eMerlin, the aim of the workshop was to bring together
observers and theorists to review the latest results. The purpose of the
workshop was to address the following issues: what are the main modes of
triggering extreme starbursts in the local Universe? How efficiently are stars
formed in extreme starbursts? What are the star formation histories of local
starburst galaxies? How well do the theoretical simulations model the
observations? What can we learn about starbursts in the distant Universe
through studies of their local counterparts? How important is the role of
extreme starbursts in the hierarchical assembly of galaxies? How are extreme
starbursts related to the triggering of AGN in the nuclei of galaxies? Overall,
41 talks and 4 posters with their corresponding 10 minutes short talks were
presented during the workshop. In addition, the workshop was designed with
emphasis on discussions, and therefore, there were 6 discussion sessions of up
to one hour during the workshop. Here is presented a summary of the purposes of
the workshop as well as a compilation of the abstracts corresponding to each of
the presentations. The summary and conclusions of the workshop along with a
description of the future prospects by Sylvain Veilleux can be found in the
last section of this document. A photo of the assistants is included.Comment: worksho
Jets and QSO Spectra
QSOs' emission lines arise from highest velocity (approximately 10000 km/s),
dense gas within approximately 0.1 parsec of the central engine, out to
low-velocity, low-density gas at great distances from the host galaxy. In
radio-loud QSOs there are clear indications that the distribution and
kinematics of emission-line gas are related to the symmetry axis of the central
engine, as defined by the radio jet. These jets originate at nuclear distances
< 0.1 pc --- similar to the highest-velocity emission line gas. There are two
ways we can investigate the different environments of radio-loud and
radio-quiet QSOs, i.e., those with and without powerful radio jets. One is to
look for optical-UV spectroscopic differences between radio-loud and
radio-quiet QSOs. The other is to investigate dependences of spectroscopic
properties on properties of the powerful jets in radio-loud QSOs. Here we
summarize the spectroscopic differences between the two classes, and present
known dependences of spectra on radio core-dominance, which we interpret as
dependences on the angle of the central engine to the line-of-sight. We
speculate on what some of the differences may mean.Comment: 10 pages, plus 2 postscript figure files not included in tex file. In
addition there is a Springer style file, lamuphys.sty. Paper to appear with
the two related papers submitted here by the same author(s), in Springer
Lecture Notes series: Jets from Stars and Galactic Nuclei, ed. W. Kund
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