From Service to Experience: Understanding and Defining the Hospitality Business

Failure adequately to define or understand hospitality as a commercial phenomenon has created a fragmented academic environment and a schizophrenia in the industry that has the potential to limit its development as a global industry. This article suggests that, by redefining hospitality as behaviour and experience, a new perspective emerges that has exciting implications for the management of hospitality businesses. A framework to describe hospitality in the commercial domain is proposed. This framework suggests a focus on the host–guest relationship, generosity, theatre and performance, ‘lots of little surprises’, and the security of strangers – a focus that provides guests with experiences that are personal, memorable and add value to their lives

Associated Absorption Lines in the Radio-Loud Quasar 3C 351: Far-Ultraviolet Echelle Spectroscopy from the Hubble Space Telescope

As one of the most luminous radio-loud quasars showing intrinsic ultraviolet (UV) and X-ray absorption, 3C 351 provides a laboratory for studying the kinematics and physical conditions of such ionized absorbers. We present an analysis of the intrinsic absorption lines in the high-resolution ($\sim$ 7 km/s) far-UV spectrum which was obtained from observations with the Space Telescope Imaging Spectrograph (STIS) on board the Hubble Space Telescope (HST). The spectrum spans wavelengths from 1150 \AA to 1710 \AA, and shows strong emission lines from O VI and Ly$\alpha$. Associated absorption lines are present on the blue wings of the high-ionization emission doublets O VI $\lambda\lambda$ 1032,1038 and N V $\lambda\lambda$ 1238,1242, as well as the Lyman lines through Ly$\epsilon$. These intrinsic absorption features are resolved into several distinct kinematic components, covering rest-frame velocities from -40 to -2800 km/s, with respect to the systemic redshift of $z_{em}=0.3721$. For the majority of these absorption line regions, strong evidence of partial covering of both the background continuum source and the BELR is found, which supports the intrinsic absorption origin and rules out the possibility that the absorption arises in some associated cluster of galaxies. The relationship between the far-UV absorbers and X-ray `warm' absorbers are studied with the assistance of photoionization models. Most of the UV associated absorption components have low values of the ionization parameter and total hydrogen column densities, which is inconsistent with previous claims that the UV and X-ray absorption arises in the same material. Analysis of these components supports a picture with a wide range of ionization parameters, temperatures, and column densities in AGN outflows.Comment: 27 pages with 5 figures, accepted by Ap

The Intrinsic Absorber in QSO 2359-1241: Keck and HST Observations

We present detailed analyses of the absorption spectrum seen in QSO 2359-1241 (NVSS J235953-124148). Keck HIRES data reveal absorption from twenty transitions arising from: He I, Mg I, Mg II, Ca II, and Fe II. HST data show broad absorption lines (BALs) from Al III 1857, C IV 1549, Si IV 1397, and N V 1240. Absorption from excited Fe II states constrains the temperature of the absorber to 2000K < T < 10,000K and puts a lower limit of 10^5 cm^{-3} on the electron number density. Saturation diagnostics show that the real column densities of He I and Fe II can be determined, allowing to derive meaningful constraints on the ionization equilibrium and abundances in the flow. The ionization parameter is constrained by the iron, helium and magnesium data to -3.0 < log(U) < -2.5 and the observed column densities can be reproduced without assuming departure from solar abundances. From comparison of the He I and Fe II absorption features we infer that the outflow seen in QSO 2359-1241 is not shielded by a hydrogen ionization front and therefore that the existence of low-ionization species in the outflow (e.g., Mg II, Al III, Fe II) does not necessitate the existence of such a front. We find that the velocity width of the absorption systematically increases as a function of ionization and to a lesser extent with abundance. Complementary analyses of the radio and polarization properties of the object are discussed in a companion paper (Brotherton et al. 2000).Comment: 30 pages, 9 figures, in press with the Ap

The FIRST Bright Quasar Survey. II. 60 Nights and 1200 Spectra Later

We have used the VLA FIRST survey and the APM catalog of the POSS-I plates as the basis for constructing a new radio-selected sample of optically bright quasars. This is the first radio-selected sample that is competitive in size with current optically selected quasar surveys. Using only two basic criteria, radio-optical positional coincidence and optical morphology, quasars and BL Lacs can be identified with 60% selection efficiency; the efficiency increases to 70% for objects fainter than magnitude 17. We show that a more sophisticated selection scheme can predict with better than 85% reliability which candidates will turn out to be quasars. This paper presents the second installment of the FIRST Bright Quasar Survey with a catalog of 636 quasars distributed over 2682 square degrees. The quasar sample is characterized and all spectra are displayed. The FBQS detects both radio-loud and radio-quiet quasars out to a redshift z>3. We find a large population of objects of intermediate radio-loudness; there is no evidence in our sample for a bimodal distribution of radio characteristics. The sample includes ~29 broad absorption line quasars, both high and low ionization, and a number of new objects with remarkable optical spectra.Comment: 41 pages plus 39 gifs which contain all quasar spectra. Accepted for publication in the Astrophysical Journal Supplement Serie

Reduction of low- and high-grade cervical abnormalities associated with high uptake of the HPV bivalent vaccine in Scotland

In Scotland, a national HPV immunisation programme began in 2008 for 12-13 year olds, with a catch-up campaign from 2008-2011 for those under the age of 18. To monitor the impact of HPV immunisation on cervical disease at the population level, a programme of national surveillance was established.  We analysed colposcopy data from a cohort of women born between 1988-1992 who entered the Scottish Cervical Screening Programme (SCSP) and were aged 20-21 in 2008-2012.  By linking datasets from the SCSP and colposcopy services, we observed a significant reduction in diagnoses of cervical intraepithelial neoplasia 1 (CIN 1) (RR 0.71, 95% CI 0.58 to 0.87, p=0.0008), CIN 2 (RR 0.5, 95% CI 0.4, 0.63, p<0.0001) and CIN 3 (RR 0.45, 95% CI 0.35 to 0.58, p< 0.0001) for women who received 3 doses of vaccine compared with unvaccinated women.  To our knowledge, this is one of the first studies to show a reduction of low and high grade cervical intraepithelial neoplasia associated with high uptake of the HPV bivalent vaccine at the population level. These data are very encouraging for countries that have achieved high HPV vaccine uptake

Radio-optical scrutiny of compact AGN: Correlations between properties of pc-scale jets and optical nuclear emission

We study the correlations between the Very Long Baseline Array radio emission at 15 GHz, extended emission at 151 MHz, and optical nuclear emission at 5100 AA for a complete sample of 135 compact jets. We use the partial Kendall's tau correlation analysis to check the link between radio properties of parsec-scale jets and optical luminosities of host AGN. We find a significant positive correlation for 99 quasars between optical nuclear luminosities and total radio (VLBA) luminosities of unresolved cores at 15 GHz originated at milliarcseconds scales. For 18 BL Lacs, the optical continuum emission correlates with the radio emission of the jet at 15 GHz. We suggest that the radio and optical emission are beamed and originate in the innermost part of the sub--parsec-scale jet in quasars. Analysis of the relation between the apparent speed of the jet and the optical nuclear luminosity at 5100 AA supports the relativistic beaming model for the optical emission generated in the jet, and allows the peak values of the intrinsic optical luminosity of the jet and its Lorentz factor to be estimated for the populations of quasars, BL Lacs, and radio galaxies. The radio-loudness of quasars is found to increase at high redshifts, which can be a result of lower efficiency of the accretion in AGN having higher radio luminosities. A strong positive correlation is found between the intrinsic kinetic power of the jet and the apparent luminosities of the total and the unresolved core emission of the jet at 15 GHz. This correlation is interpreted in terms of intrinsically more luminous parsec-scale jet producing more luminous extended structure which is detectable at low radio frequencies, 151 MHz. A possibility that the low frequency radio emission is relativistically beamed in superluminal AGN and therefore correlates with radio luminosity of the jet at 15 GHz can not be ruled out (abridged).Comment: 16 pages, 10 figuers; minor comments are added; accepted to A&

Macrocyclic colibactin induces DNA double-strand breaks via copper-mediated oxidative cleavage.

Colibactin is an assumed human gut bacterial genotoxin, whose biosynthesis is linked to the clb genomic island that has a widespread distribution in pathogenic and commensal human enterobacteria. Colibactin-producing gut microbes promote colon tumour formation and enhance the progression of colorectal cancer via cellular senescence and death induced by DNA double-strand breaks (DSBs); however, the chemical basis that contributes to the pathogenesis at the molecular level has not been fully characterized. Here, we report the discovery of colibactin-645, a macrocyclic colibactin metabolite that recapitulates the previously assumed genotoxicity and cytotoxicity. Colibactin-645 shows strong DNA DSB activity in vitro and in human cell cultures via a unique copper-mediated oxidative mechanism. We also delineate a complete biosynthetic model for colibactin-645, which highlights a unique fate of the aminomalonate-building monomer in forming the C-terminal 5-hydroxy-4-oxazolecarboxylic acid moiety through the activities of both the polyketide synthase ClbO and the amidase ClbL. This work thus provides a molecular basis for colibactin's DNA DSB activity and facilitates further mechanistic study of colibactin-related colorectal cancer incidence and prevention

Extreme Starbursts in the Local Universe

The "Extreme starbursts in the local universe" workshop was held at the Insituto de Astrofisica de Andalucia in Granada, Spain on 21-25 June 2010. Bearing in mind the advent of a new generation of facilities such as JWST, Herschel, ALMA, eVLA and eMerlin, the aim of the workshop was to bring together observers and theorists to review the latest results. The purpose of the workshop was to address the following issues: what are the main modes of triggering extreme starbursts in the local Universe? How efficiently are stars formed in extreme starbursts? What are the star formation histories of local starburst galaxies? How well do the theoretical simulations model the observations? What can we learn about starbursts in the distant Universe through studies of their local counterparts? How important is the role of extreme starbursts in the hierarchical assembly of galaxies? How are extreme starbursts related to the triggering of AGN in the nuclei of galaxies? Overall, 41 talks and 4 posters with their corresponding 10 minutes short talks were presented during the workshop. In addition, the workshop was designed with emphasis on discussions, and therefore, there were 6 discussion sessions of up to one hour during the workshop. Here is presented a summary of the purposes of the workshop as well as a compilation of the abstracts corresponding to each of the presentations. The summary and conclusions of the workshop along with a description of the future prospects by Sylvain Veilleux can be found in the last section of this document. A photo of the assistants is included.Comment: worksho

Jets and QSO Spectra

QSOs' emission lines arise from highest velocity (approximately 10000 km/s), dense gas within approximately 0.1 parsec of the central engine, out to low-velocity, low-density gas at great distances from the host galaxy. In radio-loud QSOs there are clear indications that the distribution and kinematics of emission-line gas are related to the symmetry axis of the central engine, as defined by the radio jet. These jets originate at nuclear distances < 0.1 pc --- similar to the highest-velocity emission line gas. There are two ways we can investigate the different environments of radio-loud and radio-quiet QSOs, i.e., those with and without powerful radio jets. One is to look for optical-UV spectroscopic differences between radio-loud and radio-quiet QSOs. The other is to investigate dependences of spectroscopic properties on properties of the powerful jets in radio-loud QSOs. Here we summarize the spectroscopic differences between the two classes, and present known dependences of spectra on radio core-dominance, which we interpret as dependences on the angle of the central engine to the line-of-sight. We speculate on what some of the differences may mean.Comment: 10 pages, plus 2 postscript figure files not included in tex file. In addition there is a Springer style file, lamuphys.sty. Paper to appear with the two related papers submitted here by the same author(s), in Springer Lecture Notes series: Jets from Stars and Galactic Nuclei, ed. W. Kund