Monitoring of nitrogen leaching on a dairy farm during four drainage seasons

peer-reviewedThe authors acknowledge funding from the Environmental Protection Agency and Teagasc under the 2000–2006 RTDI programme.The effect of four commonly used dairy farm management systems (treatments), on nitrogen leaching to 1 m was studied over a 4-year period from October 2001 to April 2005. The treatments were (i) grazed plots receiving dirty water, (ii) 2-cut silage plots receiving slurry, (iii) grazed plots and (iv) 1-cut silage plots receiving slurry. All plots had fertiliser N applied; the soil was free-draining overlying fissured limestone. Mean 4-year N input (kg/ha) was 319 and mean annual stocking density was ~2.38 LU/ha. The annual average and weekly NO3-N and NH4-N concentrations in drainage water were analysed for all years, using a repeated measures analysis. For the annual NO3-N data, there was an interaction between treatment and year (P < 0.001). There were significant differences (P < 0.05) in NO3-N concentrations between the treatments in all years except the third. For the NH4-N data there was no interaction between treatment and year or main effect of treatment but there were differences between years (P < 0.01). Mean weekly concentrations were analysed separately for each year. For NO3-N, in all years but the third, there was an interaction between treatment and week (P < 0.001); this occurred with NH4-N, in all 4 years. Dirty water was significantly higher than grazed-fertiliser only and 1-cut silage in NO3-N concentrations in 2001–02; in 2002–03, dirty water and 2-cut silage were significantly higher than the other treatments; while in 2004–05, dirty water and grazed-fertiliser only were significantly higher than the other two treatments. The overall 4-year mean NO3-N and NH4-N concentrations were 8.2 and 0.297 mg/L, respectively.Environmental Protection Agenc

Prevalencia de trastornos de la articulación temporomandibular y estrés académico en estudiantes de estomatología de tres universidades de Trujillo, 2019

Determinar la prevalencia de trastornos de la Articulación Temporomandibular y Estrés Académico en estudiantes de las escuelas profesionales de Estomatología de tres Universidad de Trujillo, Semestre 2019-10. Material y Método: El estudio prospectivo, transversal, descriptivo, observacional, incluyó un total de 289 estudiantes matriculados en I a X ciclos en las Escuelas Profesionales de Estomatología de tres universidades de Trujillo, Semestre 2019 - 10, utilizando el método de selección no probabilístico: por conveniencia, a quienes se evaluó a través del cuestionario Anamnesico de Fonseca validado por Rocha et al, y el cuestionario Dental Environment Stress versión en español (DES30 – Sp) validado por Fonseca et al. La información fue procesada a través de tablas estadísticas, utilizando la prueba de independencia de criterios chi cuadradro considerando un nivel de significancia de 0.05. Resultados: Se encontró que el 61.7 % de los estudiantes presentaron algún grado de trastorno de la articulación temporomandibular, siendo la prevalencia de la DTM leve, la más alta, con 138 (47.8%), seguido por DTM moderada con 32(11.1%) y DTM severa con 8 (2.8%).Además se encontró que el nivel de estrés académico percibido por los estudiantes, fue predominantemente algo estresante 205(70.9%); seguido por bastante estresante 47 (16.3%); y no estresante 37 (12.8%); mientras que no se encontraron estudiantes que perciban el entorno como muy estresante 0 (0%). Conclusiones: • La prevalencia de estudiantes de estomatología con algún grado de trastornos de la articulación temporomandibular fue mayor que los estudiantes sin trastornos de la articulación temporomandibular, siendo la DTM leve la que más prevaleció, en cuanto al estrés académico prevaleció el número de estudiantes que consideran la universidad como algo estresante.To determine the prevalence of Temporomandibular Joint disorders and Academic Stress in students of three stomatology professional schools in Trujillo Universities, Semester 2019-10. Material and Method: The prospective, cross-sectional, descriptive, observational study, include a total of 289 students enrolled from I to X semesters in the Professional Stomatology Schools of three Trujillo universities, Semester 2019-10, using the non-probabilistic selection method: For convenience, who were assessed through the Fonseca Anamnesian questionnaire validated by Rocha et al, and the Dental Environment Stress Spanish version (DES30 - Sp) questionnaire validated by Fonseca et al. The information was processed by statistical tables, using the chi-square statistical criteria independence test with significance level of 0.05. Results: It was determinated that 61.7% of the students suffered from some degree of temporomandibular joint disorder, with the prevalence of mild DTM being the highest, with 138 (47.8%), followed by moderate DTM with 32 (11.1 %) and severe DTM with 8 (2.8%). It was also determinated that the level of academic stress perceived by the students was predominantly somewhat stressful 205 (70.9%); followed by quite stressful 47 (16.3%); and not stressful at all 37 (12.8%); while none of the students perceived the environment as very stressful 0 (0%). Conclusions: • The prevalence of stomatology students with some degree of temporomandibular joint disorders was higher than students without temporomandibular joint disorders, with the mild DTM being the most prevalent, regarding of academic stress, prevailed the students who consider university as somewhat stressful.Tesi

Effect of Agricultural Practices on Nitrate Leaching

Teagasc wishes to acknowledge with gratitude funding from the 2000-2006 EPA RTDI programme in financing this research project.End of project reportA farm-scale study, carried out at Teagasc, Moorepark (Curtin’s farm), examined the effect of four managements (treatments) on nitrate-nitrogen (NO3-N) leaching over the period 2001-`05. Leaching was measured in these treatments: (T1) plots receiving dirty water and N fertilizer which were grazed; (T2) 2-cut silage and grazing plots receiving slurry and fertilizer N; (T3) grazed plots receiving fertilizer N and (T4) 1-cut silage and grazing plots receiving slurry and fertilizer N. The soil is a free-draining sandy loam overlying Karstic fissured limestone. The mean direct N inputs (kg/ha) for T1-T4 in 2001-`04 were 311, 309, 326, 331, respectively, with stocking rates (LU/ha) of 2.12 - ~2.47. Eight ceramic cups per plot, in 3 replicate plots of each treatment, were used to collect water, on a weekly basis, from 1.0 m deep using 50 kPa suction. There were 33, 37, 26 and 24 sampling dates in the 4 years, respectively. The NO3-N and NH4-N concentrations (mg/l) were determined in the water samples. The annual average and weekly concentration of these parameters was statistically analysed for all years, using a repeated measures analysis. The aggregated data were not normally distributed. There was an interaction between treatment and year (p<0.001). Significant differences (p=0.05) in NO3-N concentrations showed between the treatments in years 1, 2, 4 but not in year 3. For the NH4-N data there was no interaction between treatment and year, p=0.12, or main effect of treatment, p=0.54 but there were differences between years, p=0.01. Mean weekly concentrations were analysed separately for each year. For NO3-N, in years 1, 2 and 4 there was an interaction between treatment and week (p<0.001). With NH4-N, there was an interaction between treatment and week in all 4 years. Dirty water was significantly higher than grazed and 1 cut silage in NO3-N concentrations in year 1; in year 2, dirty water and 2 cut silage were significantly higher than the other treatments while in year 4, dirty water and grazed were significantly higher than the other two treatments. The overall four-year weighted mean NO3-N and NH4-N concentrations were 8.2 and 0.297 mg/l. The NCYCLE (UK) model was adapted for Irish conditions as NCYCLE_IRL. The NCYCLE empirical approach proved to be suitable to predict N fluxes from Irish grassland systems in most situations. Experimental data appeared to agree quite well, in most cases, with the outputs from NCYCLE_IRL. The model was not capable of predicting data from some of the leaching experiments, which suggests that the observed leaching phenomena in these experiments could be governed by non-average conditions or other parameters not accounted for in NCYCLE_IRL. An approach that took into account denitrification, leaching and herbage yield would probably explain the differences found. NCYCLE_IRL proved to be a useful tool to analyse N leaching from grazed and cut grassland systems in Ireland.Environmental Protection Agenc

A Pragmatic Trial of E-Cigarettes, Incentives, and Drugs for Smoking Cessation

In a trial examining five approaches to smoking cessation among over 6,000 U.S. employees, financial incentives combined with free cessation aids were more effective at getting employees to stop smoking than free cessation aids alone. Specifically, the most effective intervention (free cessation aids plus $600 in redeemable funds) helped 2.9% of participants stop smoking through six months after their target quit date; this rate jumped to 12.7% among participants who actively engaged in the trial and were more motivated to quit. For employees with access to usual care (information and a free motivational text messaging service), offering free cessation aids or electronic cigarettes (e-cigarettes) did not help them quit smoking

Systemic central venous oxygen saturation is associated with clot strength during traumatic hemorrhagic shock: A preclinical observational model

<p>Abstract</p> <p>Background</p> <p>Clot strength by Thrombelastography (TEG) is associated with mortality during trauma and has been linked to severity of tissue hypoperfusion. However, the optimal method for monitoring this important relationship remains undefined. We hypothesize that oxygen transport measurements will be associated with clot strength during traumatic shock, and test this hypothesis using a swine model of controlled traumatic shock.</p> <p>Methods</p> <p>N = 33 swine were subjected to femur fracture and hemorrhagic shock by controlled arterial bleeding to a predetermined level of oxygen debt measured by continuous indirect calorimetry. Hemodynamics, oxygen consumption, systemic central venous oxygenation (ScvO₂), base excess, lactate, and clot maximal amplitude by TEG (TEG-MA) as clot strength were measured at baseline and again when oxygen debt = 80 ml/kg during shock. Oxygen transport and metabolic markers of tissue perfusion were then evaluated for significant associations with TEG-MA. Forward stepwise selection was then used to create regression models identifying the strongest associations between oxygen transport and TEG-MA independent of other known determinants of clot strength.</p> <p>Results</p> <p>Multiple markers of tissue perfusion, oxygen transport, and TEG-MA were all significantly altered during shock compared to baseline measurements (p < 0.05). However, only ScvO₂demonstrated a strong bivariate association with TEG-MA measured during shock (R = 0.7, p < 0.001). ScvO₂measured during shock was also selected by forward stepwise selection as an important covariate in linear regression models of TEG-MA after adjusting for the covariates fibrinogen, pH, platelet count, and hematocrit (Whole model R²= 0.99, p ≤ 0.032).</p> <p>Conclusions</p> <p>Among multiple measurements of oxygen transport, only ScvO₂was found to retain a significant association with TEG-MA during shock after adjusting for multiple covariates. ScvO₂should be further studied for its utility as a clinical marker of both tissue hypoxia and clot formation during traumatic shock.</p

Public interest in hyaluronic acid injections for knee osteoarthritis in the United States and Europe: An international Google Trends analysis

BACKGROUND: Hyaluronic acid injections remain a common nonsurgical alternative for the treatment of knee osteoarthritis despite limited clinical evidence and varying global recommendations regarding its use. We used the Google Trends tool to provide a quantitative analysis of public interest in hyaluronic acid injections for knee osteoarthritis in the United States and Europe. METHODS: We customized Google Trends parameters to obtain search data from January 2009 to December 2019 in both the United States and Europe. Combinations of arthritis , osteoarthritis , hyaluronic acid , knee arthritis , knee osteoarthritis , and knee injection were entered into the Google Trends tool, and trend analyses were performed. RESULTS: The models generated to describe public interest in hyaluronic acid for knee injections in both the United States and Europe showed increased Google queries as time progressed ( CONCLUSIONS: Our results indicate a significant increase in Google queries related to hyaluronic acid injections for knee osteoarthritis since 2009 in both the United States and Europe. Our models suggest that despite mixed evidence supporting its use, orthopedic surgeons should expect continued public interest in hyaluronic acid for knee osteoarthritis. The results of our study may help to prepare surgeons for patient inquiries, inform the creation of evidence-based shared decision-making tools, and direct future research

Occupational Histories of Cancer Patients in a Canadian Cancer Treatment Centre and the Generated Hypothesis Regarding Breast Cancer and Farming

Occupational exposures increase cancer risks. The Windsor Regional Cancer Centre in Windsor, Ontario, was the first Canadian cancer treatment center to collect the work histories of its patients, which were recorded using a computer-based questionnaire. Breast cancer cases represented the largest respondent group. The lifetime occupational histories of 299 women with newly diagnosed breast cancers were compared with those of 237 women with other cancers. Odds ratios (ORs) were calculated using logistic regression, adjusting for age, social class, and education. The OR for women £ 55 years of age with breast cancer who had ever farmed, compared with women of the same age with other cancers, was 9.05 (95% CI 1.06, 77.43). Patients’ occupational histories can help to inform understanding of cancer etiology and prevention. This effort points to a need for investigation of the possible association between breast cancer and agricultural hazards such as pesticides

Platelets retain inducible alpha granule secretion by P‐selectin expression but exhibit mechanical dysfunction during trauma‐induced coagulopathy

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/149281/1/jth14414.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/149281/2/jth14414_am.pd

Cancer and Construction: What Occupational Histories in a Canadian Community Reveal

From 2000 to 2002, male patients at a Canadian cancer treatment center with new-incident head-and-neck or esophageal cancers were invited to participate in a population-based study. The study population included 87 cases and 172 controls. A lifetime-history questionnaire was administered. Odds ratios (ORs) were calculated for occupational groups with a minimum of five cases, adjusted for duration of employment, age, smoking, alcohol, education, and income. A significantly increased risk was shown for construction workers (OR = 2.20; 95% CI 1.25–3.91). This investigation of a set of rare cancers over a limited time period demonstrates the feasibility of this research approach. The increased risk among construction workers supports the need for more comprehensive study of exposures in this occupational group

The Prevalence and Clinical Implications of Comorbid Back Pain in Shoulder Instability: A Multicenter Orthopaedic Outcomes Network (MOON) Shoulder Instability Cohort Study.

Background:Understanding predictors of pain is critical, as recent literature shows that comorbid back pain is an independent risk factor for worse functional and patient-reported outcomes (PROs) as well as increased opioid dependence after total joint arthroplasty. Purpose/Hypothesis:The purpose of this study was to evaluate whether comorbid back pain would be predictive of pain or self-reported instability symptoms at the time of stabilization surgery. We hypothesized that comorbid back pain will correlate with increased pain at the time of surgery as well as with worse scores on shoulder-related PRO measures. Study Design:Cross-sectional study; Level of evidence, 3. Methods:As part of the Multicenter Orthopaedic Outcomes Network (MOON) Shoulder Instability cohort, patients consented to participate in pre- and intraoperative data collection. Demographic characteristics, injury history, preoperative PRO scores, and radiologic and intraoperative findings were recorded for patients undergoing surgical shoulder stabilization. Patients were also asked, whether they had any back pain. Results:The study cohort consisted of 1001 patients (81% male; mean age, 24.1 years). Patients with comorbid back pain (158 patients; 15.8%) were significantly older (28.1 vs 23.4 years; P &lt; .001) and were more likely to be female (25.3% vs 17.4%; P = .02) but did not differ in terms of either preoperative imaging or intraoperative findings. Patients with self-reported back pain had significantly worse preoperative pain and shoulder-related PRO scores (American Shoulder and Elbow Surgeons score, Western Ontario Shoulder Instability Index) (P &lt; .001), more frequent depression (22.2% vs 8.3%; P &lt; .001), poorer mental health status (worse scores for the RAND 36-Item Health Survey Mental Component Score, Iowa Quick Screen, and Personality Assessment Screener) (P &lt; .01), and worse preoperative expectations (P &lt; .01). Conclusion:Despite having similar physical findings, patients with comorbid back pain had more severe preoperative pain and self-reported symptoms of instability as well as more frequent depression and lower mental health scores. The combination of disproportionate shoulder pain, comorbid back pain and mental health conditions, and inferior preoperative expectations may affect not only the patient's preoperative state but also postoperative pain control and/or postoperative outcomes