305 research outputs found
The effect of hexobendine on the function and metabolism of the isolated, perfused rat heart
The effect of hexobendine (Ustimon R) on the function and metabolism of the isolated, perfused rat heart has been studied. Hexobendine produces a significant negative chronotropic effect, which may account for the significant reduction both in substrate uptake and metabolism and in function. Aerobic metabolism was not inhibited by hexobendine. A significant negative inotropic effect produced by hexobendine was also observed.In the light of the present study, it seems possible that hexobendine relieves angina pectoris by virtue of its negative chronotropic effect, thereby reducing the oxygen consumption of the heart
Studies in die diagnose en behandeling by gevalle va perikarditis met beklemming van die hart*
No Abstract
The South African Medical Research CouncilReview of the organisation and its first 5 years
The statutory function of control over all matters concerning medical, dental and related biological and physical research, as contained in the Act of the South African Medical Research Council No. 19 of 1969, are set out. The various research activities, administrative procedures and policies, are outlined. Special attention is drawn to the 2 institutes, viz. the National Research Institute for Occupational Diseases (NRIOD) and the National Research Institute for Nutritional Diseases (NRIND), to the 25 research units and groups, and the increasing number of individual project researchers. Allocation of funds is based on the policy that research is supported where it can best be pursued.S. Afr. Med. J., 48, 1325 (1974)
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