Colon Cancer Screening Programs: Impact of an Organized Screening Strategy Assessed by the EDIFICE Surveys

Background The aim of EDIFICE surveys is to improve insight into the behavior of the French population with regard to cancer prevention and participation in screening programs. Via the colorectal cancer screening program, all average-risk individuals in the 50-74-year age group are invited every 2 years to do a guaiac-based or, since April 2015, an immunochemical fecal occult blood test. Methods The fifth edition of the nationwide observational survey was conducted by phone interviews using the quota method. A representative sample of 1299 individuals with no history of cancer (age, 50-74 years) was interviewed between 22 November and 7 December 2016. The present analysis focuses on minimum lifetime uptake of screening tests, compliance to recommended repeat-screening intervals, and reasons for non-participation. Results In 2016, 64% survey participants had been screened at least once and 38% had been screened in the previous 2 years, suggesting a trend towards increasing participation rates, particularly in the younger age categories and among men. The 2016 data also suggest that the newly implemented FIT-based screening program has been well perceived by the population. Up to one in four individuals cited ``no risk factors'' as the reason for not undergoing screening. This reveals ignorance of the fact that the colorectal cancer screening program actually targets all average-risk individuals in a given age group, without individual risk factors. Conclusion We suggest the next step should be dedicated to educational approaches to explain exactly what screening involves and to persuasive messages targeting those who to date have remained unreceptive to information campaigns

Awareness and Misconceptions of Breast Cancer Risk Factors Among Laypersons and Physicians

Background Primary prevention of cancer relies on awareness of and consequent identification of risk factors. We investigated knowledge of breast cancer risk factors not only among laywomen but also among female physicians. Methods The EDIFICE 4 nationwide observational survey was conducted by phone interviews of a representative female population (737 laywomen and 105 female physicians) aged 40-75 years, using the quotamethod. This analysis focuses on spontaneous replies to the question ``In your opinion, what are the five main risk factors that increase the risk of breast cancer?''. Results Heredity/Family history of breast cancer was the most widely recognized risk factor in both study populations (98.1% physicians vs. 54.2% laywomen; P <= 0.01). Smoking (19.0 and 17.5%) and alcohol consumption (3.8 and 5.5%) were among the lifestyle risk factors that were cited by similar proportions of physicians and laywomen, respectively. Other established risk factors were however very rarely cited by either physicians or laywomen, e.g., Exposure tomedical radiation (4.8 vs. 0.4%, respectively; P <= 0.05) or not cited at all, i. e., Benign mastopathy and Personal history of breast cancer. Conclusion This survey highlights a number of misconceptions relating to behavioral risk factors for breast cancer, including the relative impact of alcohol and tobacco consumption and the importance of menopausal status. The limited awareness of the risk related to Exposure to medical radiation, Benign mastopathy, or Personal history raises concern regarding compliance with national screening recommendations

Perception of Lung Cancer Risk: Impact of Smoking Status and Nicotine Dependence

Background The general population is nowadays well aware that tobacco smoking dramatically increases the risk of developing lung cancer. We hypothesized that a personal history of smoking and the level of nicotine dependence in current smokers may affect the perception of this risk among healthy individuals. Methods The fourth French nationwide observational survey, EDIFICE 4, was conducted by telephone among a representative sample of individuals (N = 1602) aged between 40 and 75 years. Interviewees were asked about their smoking habits, perception of the risk of lung cancer, and nicotine dependence (Fagerstrom test). Results Regardless of their smoking status or level of nicotine dependence, the majority (96%) of our study population (N = 1463) acknowledged that tobacco smoking is a major risk factor for lung cancer. For 34% of all respondents, smoking <= 10 cigarettes per day does not carry any risk of lung cancer. Only half the current smokers considered themselves to be at higher risk of lung cancer than the average-risk population. The majority of current cigarette smokers with a nicotine dependence considered themselves to be at higher risk for lung cancer while only 37% of non-nicotine-dependent individuals had the same perception (P < 0.01). Current smokers were more likely to consider a screening examination than former smokers and never-smokers. However, the intention to undergo screening was not significantly affected by the level of nicotine dependence. Conclusions Awareness campaigns may first have to overcome misconceptions about light smoking and, secondly, to target specific populations (heavy smokers, those with a long history, highly dependent smokers)

Decline in compliance to breast cancer screening in France: Results of the 5th EDIFICE survey

San Antonio Breast Cancer Symposium, San Antonio, TX, DEC 05-09, 201

Decline in compliance to breast cancer screening in France: Results of the 5th EDIFICE survey

San Antonio Breast Cancer Symposium, San Antonio, TX, DEC 05-09, 201

Atopic dermatitis in the pediatric population: A cross-sectional, international epidemiologic study

© 2021 The Authors Background: Little is known on the current global prevalence of atopic dermatitis (AD) in the pediatric population. Objective: To estimate the real-world global prevalence of AD in the pediatric population and by disease severity. Methods: This international, cross-sectional, web-based survey of children and adolescents (6 months to \u3c18 years old) was conducted in the following 18 countries: North America (Canada, United States), Latin America (Argentina, Brazil, Columbia, Mexico), Europe (France, Germany, Italy, Spain, United Kingdom), Middle East and Eurasia (Israel, Saudi Arabia, Turkey, United Arab Emirates, Russia), and East Asia (Japan, Taiwan). Prevalence was determined using the following 2 definitions: (1) diagnosed as having AD according to the International Study of Asthma and Allergies in Childhood (ISAAC) criteria and self- or parent-report of ever being told by a physician that they or their child child had AD (eczema); and (2) reported AD based on the ISAAC criteria only. Severity was assessed using the Patient Global Assessment (PtGA) and Patient-Oriented Eczema Measure (POEM). Results: Among 65,661 responders, the 12-month diagnosed AD prevalence (ISAAC plus self-reported diagnosis) ranged from 2.7% to 20.1% across countries; reported AD (ISAAC only) was 13.5% to 41.9%. Severe AD evaluated with both PtGA and POEM was generally less than 15%; more subjects rated AD as mild on PtGA than suggested by POEM. No trends in prevalence were observed based on age or sex; prevalence was generally lower in rural residential settings than urban or suburban. Conclusion: This global survey in 18 countries revealed that AD affects a substantial proportion of the pediatric population. Although prevalence and severity varied across age groups and countries, less than 15% had severe AD

The Family Impact of Atopic Dermatitis in the Pediatric Population: Results from an International Cross-sectional Study

OBJECTIVE: To evaluate the impact of atopic dermatitis on families of pediatric subjects. STUDY DESIGN: This cross-sectional, web-based survey of children/adolescents (6 months to \u3c18 years old) with AD and their parents/caregivers was conducted in 18 countries encompassing North America, Latin America, Europe, Middle East/Eurasia, and East Asia. Children/adolescents with AD and their parents/caregivers were identified by the International Study of Asthma and Allergies in Childhood (ISAAC) criteria and ever being told by a physician that they had eczema . AD severity was assessed using Patient Oriented Eczema Measure (POEM) and Patient Global Assessment. AD impact on families\u27 lives was evaluated using the Dermatitis Family Impact questionnaire (DFI), and stand-alone questions on hours of AD-related care (past week) and missed work days (past 4 weeks) due to their child\u27s AD. RESULTS: A total of 7465 pairs of pediatric participants with AD and their parents/caregivers were surveyed. Across age groups, DFI total score for all regions ranged from 7.1-8.6, 13.2-14.9, and 17.0-17.2 for POEM mild, moderate, and severe AD, respectively; Subscale scores showed that higher AD severity had a greater impact on all family life domains, including sleep and tiredness. No specific patterns or trends were observed across age groups. Time spent on childcare and missed work days increased with AD severity. CONCLUSIONS: Across pediatric age groups and geographic regions, higher AD severity was associated with a greater negative impact on physical, emotional, social, and economic components of family life