Pontryagin's Minimum Principle based model predictive control of energy management for a plug-in hybrid electric bus

To improve computational efficiency of energy management strategies for plug-in hybrid electric vehicles (PHEVs), this paper proposes a stochastic model predictive controller (MPC) based on Pontryagin’s Minimum Principle (PMP), which differs from widely used dynamic programming (DP)-based predictive methods. First, short-time speed forecasting is achieved using a Markov chain model, based on real-world driving cycles. The PMP- and DP-based MPCs are compared under four preview horizons (5 s, 10 s, 15 s and 20 s), and the results show that the computational time of the DP-MPC is almost four times of that in the PMP-MPC. Moreover, the influence of predication horizon length on computational time and energy consumption is examined. Given a preview horizon of 5 s, the PMP-MPC holds a total energy consumption cost of 7.80 USD and computational time per second of 0.0130 s. When the preview horizon increases to 20 s, the total cost is 7.77 USD with the computational time per second increasing to 0.0502 s. Finally, DP, PMP, and rule-based strategies are contrasted to the PMP-MPC method, further demonstrating the promising performance and computational efficiency of the proposed methodology

Modelling and validation of synthesis of poly lactic acid using an alternative energy source through a continuous reactive extrusion process

PLA is one of the most promising bio-compostable and bio-degradable thermoplastic polymers made from renewable sources. PLA is generally produced by ring opening polymerization (ROP) of lactide using the metallic/bimetallic catalyst (Sn, Zn, and Al) or other organic catalysts in a suitable solvent. In this work, reactive extrusion experiments using stannous octoate Sn(Oct)2 and tri-phenyl phosphine (PPh)3 were considered to perform ROP of lactide. Ultrasound energy source was used for activating and/or boosting the polymerization as an alternative energy (AE) source. Ludovic® software, designed for simulation of the extrusion process, had to be modified in order to simulate the reactive extrusion of lactide and for the application of an AE source in an extruder. A mathematical model for the ROP of lactide reaction was developed to estimate the kinetics of the polymerization process. The isothermal curves generated through this model were then used by Ludovic software to simulate the “reactive” extrusion process of ROP of lactide. Results from the experiments and simulations were compared to validate the simulation methodology. It was observed that the application of an AE source boosts the polymerization of lactide monomers. However, it was also observed that the predicted residence time was shorter than the experimental one. There is potentially a case for reducing the residence time distribution (RTD) in Ludovic® due to the ‘liquid’ monomer flow in the extruder. Although this change in parameters resulted in validation of the simulation, it was concluded that further research is needed to validate this assumption

The evaluation and calibration of pressure mapping system for the measurement of the pressure distribution of agricultural tyres

The accuracy of a commercial pressure mapping system was evaluated and a number of techniques for the improvement of pressure measurements were developed. These were required in order to use the pressure mapping system in a tyre/surface interaction study which involved determination of the tyre contact pressure distribution on, both, hard and soil surfaces. In the evaluation of the system, the effect of sensor calibration procedures on the accuracy of the system in measuring pressure was investigated. A purpose built pressure calibration chamber was used to calibrate the sensors, which enabled the proprietary built-in calibration system to be evaluated along with a novel calibration procedure employing, both, an individual and multi-point calibration of each sensing element and the rejection of sensing elements that did not conform to the sensitivity of the majority of the sensing elements. These measures reduced the uncertainty in pressure measurements from ±30% to ±4%. Further, evaluation of the compliance of the material was also conducted to enable the sensors to be used for interface pressure measurements between two different surface materials other than those used during sensor calibration. As a result, a procedure for normalising the recorded pressure by adjusting the recorded load output to equal the applied load was established. The improvement of the accuracy of the sensors made it possible for the system to be used to determine the pressure distribution resulting from a range of tyres on a hard surface and in the soil profile

Development of CNC prototype for the characterization of the nanoparticle release during physical manipulation of nanocomposites

This work focuses on the release of nanoparticles from commercially used nanocomposites during machining operations. A reliable and repeatable method was developed to assess the intentionally exposure to nanoparticles, in particular during drilling. This article presents the description and validation of results obtained from a new prototype used for the measurement and monitoring of nanoparticles in a controlled environment. This methodology was compared with the methodologies applied in other studies. Also, some preliminary experiments on drilling nanocomposites are included. Size, shape and chemical composition of the released nanoparticles were investigated in order to understand their hazard potential. No significant differences were found in the amount of nanoparticles released between samples with and without nanoadditives. Also, no chemical alteration was observed between the dust generated and the bulk material. Finally, further developments of the prototype are proposed

Progress in environmental-friendly polymer nanocomposite material from PLA: synthesis, processing and applications

The disposal of large amounts of waste from daily use polymers is among one of the foremost concerns in the current era. Effective utilization of bio-renewable materials procured from natural sources has been proposed as a potential solution to this problem. Among such different polymers, Poly lactic acid (PLA) which is a bio-degradable polymer, resembles quite promotable features, which can be polymerized from sustainable sources as chips sugarcane, starch and corn. Ring-opening polymerization (ROP) of Lactide (LA) monomer considering catalysts such as Al, Sn or Zn is one of the efficient methods for the PLA synthesis. However, the PLA polymerized through this type of catalysts may contain trace elements of the catalyst. Due to their carcinogenic nature, the traces of such catalysts should be (ideally) removed from the synthesis process. The use of alternative energy (AE- UV, Microwave) sources could be a potential route. Alternative development of non-metal catalysts is best alternatives for the processing of PLA through ROP. PLA layer based composite materials are gaining huge interest due to their multiple application (food, medical etc.) as eco-friendly material. In this article, we review on the implementation of AE sources for PLA processing and to populate the current state-of-the-art associated with the PLA research, especially application in nanocomposite materials field

An investigation into the design of precision weeding mechanisms for inter and intra-row weed control

There is an increasing interest in the use of mechanical intra-row weeders because of concern over environmental degradation and a growing demand for organically produced food. The aim of this study was to investigate the factors that influence the design of precision weeding mechanisms for inter-and intra-row weed control. The purpose is to increase the understanding of the dynamics of the soil-machine interactions and to develop a system for either organic farming or to reduce the environmental loading of agrochemicals in conventional agriculture. Both the graphical computer simulation studies and the use of a mathematical model (O’Dogherty et al., 2007) for the kinematics of discs were used as tools to aid the disc design to determine the optimum geometric characteristics for a rotating disc that will be able to treat the intra-row area between the crop plants undisturbed circle. The model has wide applicability for the interactive design of discs for a range of crops. A force prediction model for shallow asymmetric static and rotating discs (about a vertical axis) developed to predict the forces on rotating discs. The model takes into account the geometric parameters of the discs, the speed of operation, the working depth and the physical properties of the soil based upon those required for the general soil mechanics equation which obeys the Mohr-Coulomb failure criterion. A comparison of all experimental work encompassing the laboratory experiments with non-rotating and rotating discs, incorporating the deflection effect of the shaft when working at 0o inclination angle showed that the model is able to predict the draught force with good accuracy. The predicted forces were 3.5% more than the measured forces overall for a linear regression line (with a coefficient of determination of 0.7) and 61% of the data were within bounds of ± 25% a line of equal magnitude. The effect of working depth, inclination angle and disc geometry on draught and penetration force requirements for flat and convex discs were assessed under controlled laboratory conditions. Because of its simplicity a flat disc was an obvious one to study as it is a circular blade with incorporating a cut-out sector, whilst the convex disc has the advantage of underside clearance. The effect of the concavity on soil failure proved to be of interest by providing smaller aggregates. Four inclination angles (0o - 15o) were examined at 0.5 m s-1 (1.8 km h-1) driving speed and 1 rev s-1 rotational speed at 10 mm deep. Four depths (10 mm - 25 mm) were examined at 0.5 m s-1 driving speed and 1 rev s-1 rotational speed at 10 mm deep and 0o inclination angle were tested under controlled conditions. Inclination angle and disc geometry had a significant effect on disc forces and soil failure. A small increase in inclination angle to the direction of travel reduces the magnitude of draught and vertical force by 70% and 80% respectively on average for both flat and convex disc geometries. The convex disc requires 15% less draught force than an equivalent flat disc. This allowed the optimum working parameters for a disc to be selected to eliminate the weeds with the minimum force requirements. The results of a field experiment after 16; 23; and 33 days transplanting with a working speed of 0.5 m s-1 (1.8 km h-1) showed that the proposed novel mechanical weed control system can achieve a weed reduction within the crop row up to 87%. The disc-hoe has a lower cost for an area of 125 ha of £81 ha-1,in comparison to £139 ha-1 for the inter-row and hand weeding combination and £690 ha-1 for a six man gang manual intra-row weeding, for two passes. It is also less expensive than the cost of the 24 m tractor mounted sprayer of £100 ha-1 The use of the rotating disc-hoe for mechanical weed control would have the benefits of lower mechanical weeding cost, increased potential for organic production and reduction in the number of weeding operations through better targeting to minimise problems caused by frequent soil disturbance and reduced herbicide use having the benefits of environmental advantage.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Subtumoral analysis of PRINT nanoparticle distribution reveals targeting variation based on cellular and particle properties

AbstractThe biological activity of nanoparticle-directed therapies critically depends on cellular targeting. We examined the subtumoral fate of Particle Replication in Non-Wetting Templates (PRINT) nanoparticles in a xenografted melanoma tumor model by multi-color flow cytometry and in vivo confocal tumor imaging. These approaches were compared with the typical method of whole-organ quantification by radiolabeling. In contrast to radioactivity based detection which demonstrated a linear dose-dependent accumulation in the organ, flow cytometry revealed that particle association with cancer cells became dose-independent with increased particle doses and that the majority of the nanoparticles in the tumor were associated with cancer cells despite a low fractional association. In vivo imaging demonstrated an inverse relationship between tumor cell association and other immune cells, likely macrophages. Finally, variation in particle size nonuniformly affected subtumoral association. This study demonstrates the importance of subtumoral targeting when assessing nanoparticle activity within tumors.From the Clinical EditorParticle Replication in Non-Wetting Templates (PRINT) technology allows the production of nanoparticles with uniform size. The authors in the study utilized PRINT-produced nanoparticles to investigate specific tumor uptake by multi-color flow cytometry and in vivo confocal tumor imaging. This approach allowed further in-depth correlation between nanoparticle properties and tumor cells and should improve future design

Tortuous Microvessels Contribute to Wound Healing via Sprouting AngiogenesisHighlights

Wound healing is accompanied by neoangiogenesis, and new vessels are thought to originate primarily from the microcirculation; however, how these vessels form and resolve during wound healing is poorly understood. Here, we investigated properties of the smallest capillaries during wound healing to determine their spatial organization and the kinetics of formation and resolution

Investigation of the effect of temperature on lithium-sulfur cell cycle life performance using system identification and x-ray tomography

In this study, cycle life performance of a prototype lithium-sulfur (Li−S) pouch cell is investigated using system identification and X-ray tomography methods. Li−S cells are subjected to characterization and ageing tests while kept inside a controlled-temperature chamber. After completing the experimental tests, two analytical approaches are used: i) The parameter variations of an equivalent-circuit model due to ageing are determined using a system identification technique. ii) Physical changes of the aged Li−S cells are analyzed using X-ray tomography. The results demonstrate that Li−S cell's degradation is significantly affected by temperature. Comparing to 10 °C, Li−S cell capacity fade happens 1.4 times faster at 20 °C whereas this number increases to 3.3 at 30 °C. In addition, X-ray results show a significant swelling when temperature rises from 10 to 20 °C, correspondingly the gas volume increases from 13 to 62 mm3.Innovate UK: TS/R013780/1. European Union funding: 814471. Engineering and Physical Sciences Research Council (EPSRC): EP/S003053/1, FIRG014, FIRG027

An African Ancestry-Specific Allele of CTLA4 Confers Protection against Rheumatoid Arthritis in African Americans

Cytotoxic T-lymphocyte associated protein 4 (CTLA4) is a negative regulator of T-cell proliferation. Polymorphisms in CTLA4 have been inconsistently associated with susceptibility to rheumatoid arthritis (RA) in populations of European ancestry but have not been examined in African Americans. The prevalence of RA in most populations of European and Asian ancestry is ∼1.0%; RA is purportedly less common in black Africans, with little known about its prevalence in African Americans. We sought to determine if CTLA4 polymorphisms are associated with RA in African Americans. We performed a 2-stage analysis of 12 haplotype tagging single nucleotide polymorphisms (SNPs) across CTLA4 in a total of 505 African American RA patients and 712 African American controls using Illumina and TaqMan platforms. The minor allele (G) of the rs231778 SNP was 0.054 in RA patients, compared to 0.209 in controls (4.462×10−26, Fisher's exact). The presence of the G allele was associated with a substantially reduced odds ratio (OR) of having RA (AG+GG genotypes vs. AA genotype, OR 0.19, 95% CI: 0.13–0.26, p = 2.4×10−28, Fisher's exact), suggesting a protective effect. This SNP is polymorphic in the African population (minor allele frequency [MAF] 0.09 in the Yoruba population), but is very rare in other groups (MAF = 0.002 in 530 Caucasians genotyped for this study). Markers associated with RA in populations of European ancestry (rs3087243 [+60C/T] and rs231775 [+49A/G]) were not replicated in African Americans. We found no confounding of association for rs231778 after stratifying for the HLA-DRB1 shared epitope, presence of anti-cyclic citrullinated peptide antibody, or degree of admixture from the European population. An African ancestry-specific genetic variant of CTLA4 appears to be associated with protection from RA in African Americans. This finding may explain, in part, the relatively low prevalence of RA in black African populations