Partnering in oncogenetic research – the INHERIT BRCAs experience : opportunities and challenges

Today it is common to conduct research in collaboration with colleagues from different disciplines and institutions. The INterdisciplinary HEalth Research International Team on BReast CAncer susceptibility (INHERIT BRCAs), involves Canadian and international experts from diverse fields working with health service providers, patients and collaborators from the World Health Organization and other European networks. Evidence-based information and knowledge transfer drive our efforts to advance genomic research to understand the genetic basis of cancer susceptibility and treatment response. Several goals reveal the interdisciplinary team approach: (a) to estimate the prevalence and penetrance of BRCA1 and BRCA2 mutations and their deleterious impact upon different populations; (b) to pinpoint novel breast cancer susceptibility loci; (c) to assess the efficacy of clinical interventions; (d) to address changes in quality of life and health-related behaviour from the decision to undergo genetics testing and during follow-up; (e) to evaluate legal, social and ethical implications; and, finally; (f) to promote professional and public education by facilitating the transfer of research findings to clinical practice and informing policy makers. The lessons learned by the INHERIT research team and future challenges are presented

INHERIT BRCAs Partnering in Oncogenetic Research – The INHERIT BRCAs Experience: Opportunities and Challenges

[À l'origine dans / Was originally part of : CRDP - Droit, biotechnologie et rapport au milieu

The Middle East in the world hierarchy:imperialism and resistance

This study deploys a structuralist framework of analysis, modified by elements from other theories, to examine the place of the Middle East in the world hierarchy. It surveys the origins of the regional system in imperialism's peripheralisation and fragmentation of the region, the core-periphery clientalist hierarchy thereby established, regional agency within the system, including the foreign policies of dependent and rebellious states, and the on-going struggle over the hierarchical order between revisionist forces in the Middle East and the global hegemons