Conservation of Arabidopsis thaliana photoperiodic flowering time genes in onion (Allium cepa L.)

The genetics underlying onion development is poorly understood. Here the characterisation of onion homologues of Arabidopsis photoperiodic flowering pathway genes is reported with the end goal of accelerating onion breeding programmes by understanding the genetic basis of adaptation to different latitudes. The expression of onion GI, FKF1 and ZTL homologues under SD and LD conditions was examined using quantitative RT-PCR. The expression of AcGI and AcFKF1 was examined in onion varieties which exhibit different daylength responses. Phylogenetic trees were constructed to confirm the identity of the homologues. AcGI and AcFKF1 showed diurnal expression patterns similar to their Arabidopsis counterparts while AcZTL was found to be constitutively expressed. AcGI showed similar expression patterns in varieties which exhibit different daylength responses whereas AcFKF1 showed differences. It is proposed that these differences could contribute to the different daylength responses in these varieties. Phylogenetic analyses showed that all the genes isolated are very closely related to their proposed homologues. The results presented here show that key genes controlling photoperiodic flowering in Arabidopsis are conserved in onion and a role for these genes in the photoperiodic control of bulb initiation is predicted. This theory is supported by expression and phylogenetic data

Informed Search for Learning Causal Structure

Over the past twenty-five years, a large number of algorithms have been developed to learn the structure of causal graphical models. Many of these algorithms learn causal structures by analyzing the implications of observed conditional independence among variables that describe characteristics of the domain being analyzed. They do so by applying inference rules, data analysis operations such as the conditional independence tests, each of which can eliminate large parts of the space of possible causal structures. Results show that the sequence of inference rules used by PC, a widely applied algorithm for constraint-based learning of causal models, is effective but not optimal. This is because algorithms such as PC ignore the probability of the outcomes of these inference rules. We demonstrate how an alternative algorithm can reliably outperform PC by taking into account the probability of inference rule outcomes. Specifically we show that an informed search that bases the order of causal inference on a prior probability distribution over the space of causal constraints can generate a flexible sequence of analysis that efficiently identifies the same results as PC. This class of algorithms is able to outperform PC even under uniform or erroneous priors

Dynamical Decompactification and Three Large Dimensions

We study string gas dynamics in the early universe and seek to realize the Brandenberger - Vafa mechanism - a goal that has eluded earlier works - that singles out three or fewer spatial dimensions as the number which grow large cosmologically. Considering wound string interactions in an impact parameter picture, we show that a strong exponential suppression in the interaction rates for d > 3 spatial dimensions reflects the classical argument that string worldsheets generically intersect in at most four spacetime dimensions. This description is appropriate in the early universe if wound strings are heavy - wrapping long cycles - and diluted. We consider the dynamics of a string gas coupled to dilaton-gravity and find that a) for any number of dimensions the universe generically stays trapped in the Hagedorn regime and b) if the universe fluctuates to a radiation regime any residual winding modes are diluted enough so that they freeze-out in d > 3 large dimensions while they generically annihilate for d = 3. In this sense the Brandenberger-Vafa mechanism is operative.Comment: 20 pages, 2 figures, minor changes, updated figures, as will appear in Phys.Rev.

Paternal Psychosocial Characteristics and Corporal Punishment of their 3-Year Old Children

This study uses data from 2,309 biological fathers who participated in the Fragile Families and Child Wellbeing Study (FFCWS) to examine associations between psychosocial characteristics and levels of corporal punishment (CP) toward their 3-year old children over the past month. Results indicate that 61% of the fathers reported no CP over the past month, 23% reported using CP once or twice, and 16% reported using CP a few times in the past month or more. In multivariate models controlling for important socio-demographic factors as well as characteristics of the child, fathers’ parenting stress, major depression, alcohol use, and drug use were significantly associated with greater use of CP, whereas involvement with the child and generalized anxiety order were not. Girls were less likely to be the recipient of CP than boys, and child externalizing behavior problems but not internalizing behavior problems were associated with more CP.Fragile families, childbearing, nonmarital childbearing, fartherhood, fathers, corporal punishment, behavior problems, stress, depression