Visual Imprinting in Birds: Behavior, Models, and Neural Mechanisms.

Filial imprinting is a process, readily observed in precocial birds, whereby a social attachment is established between a young animal and an object that is typically (although not necessarily) a parent. During a perinatal sensitive period, the young animal learns characteristics of the object (the imprinting stimulus) simply by being exposed to it and will subsequently recognize and selectively approach this stimulus. Imprinting can thus establish a filial bond with an individual adult: a form of social cohesion that may be crucial for survival. Behavioral predispositions can act together with the learning process of imprinting in the formation, maintenance, and modification of the filial bond. Memory of the imprinting stimulus, as well as being necessary for social recognition, is also used adaptively in perceptual classification of sensory signals. Abstract features of an imprinting stimulus, such as similarity or difference between stimulus components, can also be recognized. Studies of domestic chicks have elucidated the neural basis of much of the above behavior. This article discusses (1) principal behavioral characteristics of filial imprinting and related predispositions, (2) theoretical models that have been developed to account for this behavior, and (3) physiological results elucidating the underlying neural mechanisms. Interactions between these different levels of analysis have resulted in advancement of all of them. Taken together, the different approaches have helped define strategies for investigating mechanisms of learning, memory, and perception

The Social Life of Mortgage Delinquency and Default

Although falling behind on a mortgage loan has significant personal consequences, we know little about whether the experience of delinquency or default influences the housing market behavior of other people in the defaulter's social networks. In this article, I ask how exposure to mortgage default through social networks affects perceptions of the housing market, judgments about the strategic default behavior of other households, and expectations for homeownership. Although individuals purposively draw on information from their social networks to aid in their housing search, theories of social influence have yet to be applied to the negative experience of mortgage delinquency or default. Drawing on the National Housing Survey, I find that individuals exposed to mortgage strain through their social networks express more negative expectations for the housing market and hold more permissive attitudes about strategic default. Homeowners reporting network exposure to mortgage strain are more likely to prefer rental housing when they next move. These results are strongest when individuals are connected to someone who has fallen behind on a mortgage payment in the previous three months

Coping with Natural Hazards in a Conservation Context: Resource-Use Decisions of Maasai Households During Recent and Historical Droughts

Analyzing people’s decisions can reveal key variables that affect their behaviors. Despite the demonstrated utility of this approach, it has not been applied to livelihood decisions in the context of conservation initiatives. We used ethnographic decision modeling in combination with qualitative comparative analysis (QCA) to examine the herding decisions of Maasai households living near Tarangire National Park (TNP) during recent and historical droughts. The effects of the establishment of TNP on herding practices during drought were different than anticipated based on the size and reliability of several prominent resource areas that are now within the park. We found little evidence of people relying on these swamps and rivers for watering cattle during historical droughts; rather, these sites were more commonly used as grazing areas for small stock and wet-season grazing areas for cattle to avoid disease carried by calving wildebeest. Yet during the 2009 drought, many herders moved their livestock – especially cattle from outside of the study area – toward TNP in search of grazing. Our analysis of herding decisions demonstrates that resource-use decisions are complex and incorporate a variety of information beyond the size or reliability of a given resource area, including contextual factors (e.g., disease, conflict, grazing) and household factors (e.g., social capital, labor, herd size). More broadly, this research illustrates that pairing decision modeling with QCA is a structured approach to identifying these factors and understanding how opportunities, constraints, and perceptions influence how people respond to changes in resource access

Physiological levels of lipoxin A4 inhibit ENaC and restore airway surface liquid height in cystic fibrosis bronchial epithelium.

In cystic fibrosis (CF), the airway surface liquid (ASL) is depleted. We previously demonstrated that lipoxin A4 (LXA4) can modulate ASL height (ASLh) through actions on Cl(-) transport. Here, we report novel effects of lipoxin on the epithelial Na(+) channel ENaC in this response. ASL dynamics and ion transport were studied using live-cell confocal microscopy and short-circuit current measurements in CF (CuFi-1) and non-CF (NuLi-1) cell cultures. Low physiological concentrations of LXA4 in the picomolar range produced an increase in ASLh which was dependent on inhibition of an amiloride-sensitive Na(+) current and stimulation of a bumetanide-sensitive Cl(-) current. These ion transport and ASLh responses to LXA4 were blocked by Boc-2 an inhibitor of the specific LXA4 receptor ALX/FPR2. LXA4 affected the subcellular localization of its receptor and enhanced the localization of ALX/FPR2 at the apical membrane of CF cells. Our results provide evidence for a novel effect of low physiological concentrations of LXA4 to inhibit airway epithelial Na(+) absorption that results in an ASL height increase in CF airway epithelia

Neuronal Plasticity and Multisensory Integration in Filial Imprinting

Many organisms sample their environment through multiple sensory systems and the integration of multisensory information enhances learning. However, the mechanisms underlying multisensory memory formation and their similarity to unisensory mechanisms remain unclear. Filial imprinting is one example in which experience is multisensory, and the mechanisms of unisensory neuronal plasticity are well established. We investigated the storage of audiovisual information through experience by comparing the activity of neurons in the intermediate and medial mesopallium of imprinted and naïve domestic chicks (Gallus gallus domesticus) in response to an audiovisual imprinting stimulus and novel object and their auditory and visual components. We find that imprinting enhanced the mean response magnitude of neurons to unisensory but not multisensory stimuli. Furthermore, imprinting enhanced responses to incongruent audiovisual stimuli comprised of mismatched auditory and visual components. Our results suggest that the effects of imprinting on the unisensory and multisensory responsiveness of IMM neurons differ and that IMM neurons may function to detect unexpected deviations from the audiovisual imprinting stimulus

The Journal of Microelectronic Research 2009

https://scholarworks.rit.edu/meec_archive/1017/thumbnail.jp

Infrared Ellipsometry Analysis of Heritage Photographic Prints

[EN] Focusing on the photographic archive of Julian Carrillo (Mexico), we study and characterize the photographic processes of a set of 13 photographs dated between 1884 and 1925. By using infrared spectroscopic ellipsometry, we classified a selected set of photographs according to its kind of binder. Thus, we recognized for each photograph, the presence of proteins, and therefore, the particular photographic process. Furthermore, we have identified the presence of baryta layer, the use of plasticizer, and the eventual coating utilized to protect the photograph, whose composition was based in natural organic components, mainly shellac, beeswax, or camphorNieto-Villena, A.; Martinez, JR.; Flores-Camacho, JM.; Lastras-Martinez, A.; De La Cruz-Mendoza, JA.; Ortega-Zarzosa, G.; Valcarcel Andrés, JC.... (2018). Infrared Ellipsometry Analysis of Heritage Photographic Prints. Studies in Conservation. 63(8):466-476. https://doi.org/10.1080/00393630.2018.1476962S466476638Brambilla, L., Riedo, C., Baraldi, C., Nevin, A., Gamberini, M. C., D’Andrea, C., … Toniolo, L. (2011). Characterization of fresh and aged natural ingredients used in historical ointments by molecular spectroscopic techniques: IR, Raman and fluorescence. Analytical and Bioanalytical Chemistry, 401(6), 1827-1837. doi:10.1007/s00216-011-5168-zCasoli, A., & Fornaciari, S. (2014). An analytical study on an early twentieth-century Italian photographs collection by means of microscopic and spectroscopic techniques. Microchemical Journal, 116, 24-30. doi:10.1016/j.microc.2014.04.003Cattaneo, B., Chelazzi, D., Giorgi, R., Serena, T., Merlo, C., & Baglioni, P. (2008). Physico-chemical characterization and conservation issues of photographs dated between 1890 and 1910. Journal of Cultural Heritage, 9(3), 277-284. doi:10.1016/j.culher.2008.01.004Daher, C., Paris, C., Le Hô, A.-S., Bellot-Gurlet, L., & Échard, J.-P. (2010). A joint use of Raman and infrared spectroscopies for the identification of natural organic media used in ancient varnishes. Journal of Raman Spectroscopy, 41(11), 1494-1499. doi:10.1002/jrs.2693Edwards, H. G. M., Farwell, D. W., & Daffner, L. (1996). Fourier-transform Raman spectroscopic study of natural waxes and resins. I. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 52(12), 1639-1648. doi:10.1016/0584-8539(96)01730-8Fujiwara, H. (2007). Spectroscopic Ellipsometry. doi:10.1002/9780470060193Hendriks, K., & Ross, L. (1988). Chemical Treatments of Discoloured Photographic Prints: Image Manipulation or Legitimate Restoration? The Journal of Photographic Science, 36(3), 132-132. doi:10.1080/00223638.1988.11736990Mallégol, J., Gardette, J.-L., & Lemaire, J. (2000). Long-term behavior of oil-based varnishes and paints. Photo- and thermooxidation of cured linseed oil. Journal of the American Oil Chemists’ Society, 77(3), 257-263. doi:10.1007/s11746-000-0042-4Nieto-Villena, A., Martínez, J. R., de la Cruz-Mendoza, J. A., Valcárcel-Andrés, J. C., Ortega-Zarzosa, G., Solbes-García, Á., & Vázquez-Martínez, E. (2018). Atomic force microscopy as a tool for binder identification in ancient photographic processes. Surface and Interface Analysis, 50(4), 496-505. doi:10.1002/sia.6408Ostroff, Eugene. 1966. “Restoration of Photographs by Neutron Activation.” Science 154 (3745): 119–123. http://science.sciencemag.org/content/154/3745/119.Othmer, Kirk, ed. 2005. Encyclopedia of Chemical Technology. Vol. 17, 5th ed. New York: Wiley.Ricci, C., Bloxham, S., & Kazarian, S. G. (2007). ATR-FTIR imaging of albumen photographic prints. Journal of Cultural Heritage, 8(4), 387-395. doi:10.1016/j.culher.2007.07.002Sifontes, Á. B., Cañizales, E., Toro-Mendoza, J., Ávila, E., Hernández, P., Delgado, B. A., … Cruz-Barrios, E. (2015). Obtaining Highly Crystalline Barium Sulphate Nanoparticles via Chemical Precipitation and Quenching in Absence of Polymer Stabilizers. Journal of Nanomaterials, 2015, 1-8. doi:10.1155/2015/510376Stulik, Dusan, Herant Khanjian, Alberto de Tagle, and Alexandra M. Botelho. 2002. “Investigation of Jean-Louis-Marie-Eugene Durieu’s Toning and Varnishing Experiments: A Non-Destructive Approach.” ICOM Committee for Conservation 13th Triennial Meeting, Río de Janeiro, 658–663.Price, Beth A., and Boris Pretzel, eds. 2009. Infrared and Raman Users Group Spectral Database. 2007 ed. Vol. 1 & 2. Philadelphia: IRUG. Accessed June 20, 2014. http://www.irug.org/.Vila, A., & Centeno, S. A. (2013). FTIR, Raman and XRF identification of the image materials in turn of the 20th century pigment-based photographs. Microchemical Journal, 106, 255-262. doi:10.1016/j.microc.2012.07.01

Right Isomerism of the Brain in Inversus Viscerum Mutant Mice

Left-right (L-R) asymmetry is a fundamental feature of higher-order neural function. However, the molecular basis of brain asymmetry remains unclear. We recently reported L-R asymmetry of hippocampal circuitry caused by differential allocation of N-methyl-D-aspartate receptor (NMDAR) subunit GluRε2 (NR2B) in hippocampal synapses. Using electrophysiology and immunocytochemistry, here we analyzed the hippocampal circuitry of the inversus viscerum (iv) mouse that has a randomized laterality of internal organs. The iv mouse hippocampus lacks L-R asymmetry, it exhibits right isomerism in the synaptic distribution of the ε2 subunit, irrespective of the laterality of visceral organs. This independent right isomerism of the hippocampus is the first evidence that a distinct mechanism downstream of the iv mutation generates brain asymmetry

Insect-Specific microRNA Involved in the Development of the Silkworm Bombyx mori

MicroRNAs (miRNAs) are endogenous non-coding genes that participate in post-transcription regulation by either degrading mRNA or blocking its translation. It is considered to be very important in regulating insect development and metamorphosis. We conducted a large-scale screening for miRNA genes in the silkworm Bombyx mori using sequence-by-synthesis (SBS) deep sequencing of mixed RNAs from egg, larval, pupal, and adult stages. Of 2,227,930 SBS tags, 1,144,485 ranged from 17 to 25 nt, corresponding to 256,604 unique tags. Among these non-redundant tags, 95,184 were matched to the silkworm genome. We identified 3,750 miRNA candidate genes using a computational pipeline combining RNAfold and TripletSVM algorithms. We confirmed 354 miRNA genes using miRNA microarrays and then performed expression profile analysis on these miRNAs for all developmental stages. While 106 miRNAs were expressed in all stages, 248 miRNAs were egg- and pupa-specific, suggesting that insect miRNAs play a significant role in embryogenesis and metamorphosis. We selected eight miRNAs for quantitative RT-PCR analysis; six of these were consistent with our microarray results. In addition, we searched for orthologous miRNA genes in mammals, a nematode, and other insects and found that most silkworm miRNAs are conserved in insects, whereas only a small number of silkworm miRNAs has orthologs in mammals and the nematode. These results suggest that there are many miRNAs unique to insects