405 research outputs found

    Future Learning Spaces: Space, Technology and Pedagogy

    Get PDF
    Learning can and does happen anywhere. Sometimes that learning occurs in classrooms (formal learning), other times it results from face-to-face and virtual encounters and interactions between individuals away from lecture halls and seminar rooms (social or informal learning). Space – whether physical or virtual, individual or shared – can have an important impact on learning. It can bring people together; it can encourage exploration, collaboration and discussion; it can also frame an unspoken message of exclusion, disconnectedness and disengagement (Oblinger, 2006). Higher education institutions are growing increasingly aware of the power of “built pedagogy” (Monahan, 2002) – the ability of spaces to shape and define how educators teach their students – and with it an attitude underlining the orthodox view of higher education learning spaces that has tended to treat space and learning as two related but separate domains of academic life

    Cage\u27s Dungeon

    Get PDF
    Cage’s Dungeon specifically refers to the work of the influential composer, performer, writer, and philosopher, John Cage. More precisely, his later compositional style which emphasized the use of chance operations within a musical composition. Cage was highly influenced by eastern philosophy, Zen Buddhism in particular, and he was fascinated by the chance operations found in the ancient I Ching text. As a result, Cage wrote many works that were nothing more than a set of simple guidelines for the performer to follow, with the outcome of the process creating the piece. These indeterminate compositions are not so much about the technical prowess of the performer or composer, or even about making a profound artistic statement. Instead, Cage’s chance music creates an opportunity for unique and interesting sounds to interact with one another in a unique way

    Music Recommendations in Hyperbolic Space: An Application of Empirical Bayes and Hierarchical Poincar\'e Embeddings

    Full text link
    Matrix Factorization (MF) is a common method for generating recommendations, where the proximity of entities like users or items in the embedded space indicates their similarity to one another. Though almost all applications implicitly use a Euclidean embedding space to represent two entity types, recent work has suggested that a hyperbolic Poincar\'e ball may be more well suited to representing multiple entity types, and in particular, hierarchies. We describe a novel method to embed a hierarchy of related music entities in hyperbolic space. We also describe how a parametric empirical Bayes approach can be used to estimate link reliability between entities in the hierarchy. Applying these methods together to build personalized playlists for users in a digital music service yielded a large and statistically significant increase in performance during an A/B test, as compared to the Euclidean model

    The correlation of force-velocity-power relationship of a whole-body movement with 20 m and 60 m sprint performance

    Get PDF
    Sprinting ability is important for successful performance in sports. The aim of this study was to examine the correlation between force-velocity-power relationship of a whole-body movement and sprint performance. Twelve male participants performed maximal squat jumps with additional loads ranging from 0% to 100% body weight to obtain force-velocity profiles. The mean force and velocity were calculated during the push-off phase for each jump, which resulted in a force-velocity curve. The theoretical maximal force (F0), theoretical maximal velocity (V0) and theoretical maximum power (P0) were computed via extrapolation of the force and velocity data. In the second session, participants performed two 60 m sprints and the time to cover 20 m (t20), time to cover 60 m (t60), and maximum sprint velocity (Vmax) were calculated from the best 60 m trial. Correlation analyses revealed strong and significant correlations between V0 and t20 (r = −0.60), V0 and t60 (r = −0.60), P0 and t20 (r = −0.75) and P0 and t60 (r = −0.78). Multiple linear regression indicated that P0 explained 56%, 61% and 60% of the variability in t20, t60 and Vmax, respectively. Our results emphasise the importance of developing power production capabilities to improve sprint performance

    A blended learning model for first year science student engagement with mathematics and statistics

    Get PDF
    With the rapid decline of the enrolments in the conventional, campus-based courses, many higher education (HE) institutions around the world opt for provision of dual learning and teaching modes, most often offering fully online experiences in off-campus courses (distance education), and hybrid/ blended learning experiences in on-campus courses. This raises questions related to the quality of technology-enhanced learning (TEL) and teaching experiences (Laurillard, 2009; Kirkwood, 2014). TEL is maturing and entering a normalization phase, with modes such as blended learning expected to become the “new traditional model” or “the new normal” of course delivery mode (Porter et al., 2016) within one or two years (Johnson, Adams Becker, Estrada & Freeman, 2015). This normalisation shifts research paradigm from investigation of the ways the ICTs are used within educational settings to more focused analysis of pedagogical aspects impacting the design and implementation of the integrated ICTs. A rigorous, research-informed investigation is needed to scrutinise factors influencing effective integration of ICTs in the curricula, impact the integrated ICTs have on both teaching and learning, their effectiveness within current environment and the transferability/ adaptability of developed model(s) to other contexts (Kirkwood, 2014). This presentation reports on an informed inquiry investigating the effectiveness of the redesigned technology-enhanced learning and teaching environment in promoting student engagement in a compulsory quantitative methods unit for first year science undergraduates offered at a large, metropolitan university. A blended learning model was adopted including pre-lecture readings, didactic lectures, self-paced computer labs with demonstration videos, collaborative workshops, fortnightly online quizzes, and problem solving tasks based on realistic quantitative analysis. Teaching resources were highly structured and made available to students using Adaptive Release feature, a part of the University’s Blackboard Learning Management System. The Adaptive Release was introduced to foster students’ engagement and encourage students’ self-regulated learning, with focus on assisting students with resource development of management strategies. Quantitative data was collected through access logs on the Blackboard Learning Management System, social media activity within closed groups, an investigation of mathematical background at admission, workshop attendance and unit assessment results. The data analysis used statistical modelling which allowed researchers to demonstrate correlations between student’s preparedness level, engagement and success

    Influenza research database: an integrated bioinformatics resource for influenza research and surveillance.

    Get PDF
    BackgroundThe recent emergence of the 2009 pandemic influenza A/H1N1 virus has highlighted the value of free and open access to influenza virus genome sequence data integrated with information about other important virus characteristics.DesignThe Influenza Research Database (IRD, http://www.fludb.org) is a free, open, publicly-accessible resource funded by the U.S. National Institute of Allergy and Infectious Diseases through the Bioinformatics Resource Centers program. IRD provides a comprehensive, integrated database and analysis resource for influenza sequence, surveillance, and research data, including user-friendly interfaces for data retrieval, visualization and comparative genomics analysis, together with personal log in-protected 'workbench' spaces for saving data sets and analysis results. IRD integrates genomic, proteomic, immune epitope, and surveillance data from a variety of sources, including public databases, computational algorithms, external research groups, and the scientific literature.ResultsTo demonstrate the utility of the data and analysis tools available in IRD, two scientific use cases are presented. A comparison of hemagglutinin sequence conservation and epitope coverage information revealed highly conserved protein regions that can be recognized by the human adaptive immune system as possible targets for inducing cross-protective immunity. Phylogenetic and geospatial analysis of sequences from wild bird surveillance samples revealed a possible evolutionary connection between influenza virus from Delaware Bay shorebirds and Alberta ducks.ConclusionsThe IRD provides a wealth of integrated data and information about influenza virus to support research of the genetic determinants dictating virus pathogenicity, host range restriction and transmission, and to facilitate development of vaccines, diagnostics, and therapeutics

    Mitogen-activated protein kinase phosphatase-2 deletion impairs synaptic plasticity and hippocampal-dependent memory

    Get PDF
    Mitogen-activated protein kinases (MAPKs) regulate brain function and their dysfunction is implicated in a number of brain disorders, including Alzheimer’s disease. Thus there is great interest in understanding the signalling systems that control MAPK function. One family of proteins that contribute to this process, the mitogen-activated protein kinase phosphatases (MKPs), directly inactivate MAPKs through dephosphorylation. Recent studies have identified novel functions of MKPs in development, the immune system and cancer. However, a significant gap in our knowledge remains in relation to their role in brain functioning. Here, using transgenic mice where the Dusp4 gene encoding MKP-2 has been knocked out (MKP-2-/- mice), we show that long-term potentiation (LTP) is impaired in MKP-2-/- mice compared to MKP-2+/+ controls whereas neuronal excitability, evoked synaptic transmission and paired-pulse facilitation remain unaltered. Furthermore, spontaneous excitatory postsynaptic currents (sEPSC) frequency was increased in acute slices and primary hippocampal cultures prepared from MKP-2-/- mice with no effect on EPSC amplitude observed. An increase in synapse number was evident in primary hippocampal cultures which may account for the increase in spontaneous EPSC frequency. In addition no change in ERK activity was detected in both brain tissue and primary hippocampal cultures, suggesting that the effects of MKP-2 deletion were MAPK independent. Consistent with these alterations in hippocampal function, MKP-2-/- mice show deficits in spatial reference and working memory when investigated using the Morris water maze. These data show that MKP-2 plays a role in regulating hippocampal function and that this effect may be independent of MAPK signalling

    Violence, alcohol and symptoms of depression and in Cape Town's poorest communities: results of a community survey

    Get PDF
    Introduction This paper summarises key findings from the first of three household surveys conducted in three high-violence areas in the Cape Town, investigating community members’ experiences of alcohol use, their built environment, violence and symptoms of depression, together with their views on alcohol and other interventions. Methods A stratified random sample of 1500 dwellings, 1200 in Khayelitsha and 300 in Gugulethu and Nyanga (“Gunya”) was selected using GIS address data for formal areas and aerial photography for informal areas. Fieldwork took place from July to November 2013. Responses to questions were summarized by area, gender, age and formal vs. informal settlement type. Results After substitution and data cleaning, 1213 Khayelitsha households and 286 Gunya households were included. In Gunya, 29% of respondents reported that they or their family members had been affected by at least one violent crime (murder, assault, domestic violence, rape) in the past year, compared with 12% in Khayelitsha. Using a CES-D-10 cut-off of 10, 44% of respondents were classified as depressed. More than half the respondents reported having experienced some form of alcohol nuisance. Respondents were supportive of alcohol interventions such as increased taxes and police regulation of outlets, particularly in Gunya (87%) and amongst female respondents (76%). Satisfaction with infrastructure such as street lighting and drainage was generally low. Conclusions The results describe the co-occurring burdens of alcohol and drug use, violence, depression and deprivation in our study populations

    Towards Space-like Photometric Precision from the Ground with Beam-Shaping Diffusers

    Get PDF
    We demonstrate a path to hitherto unachievable differential photometric precisions from the ground, both in the optical and near-infrared (NIR), using custom-fabricated beam-shaping diffusers produced using specialized nanofabrication techniques. Such diffusers mold the focal plane image of a star into a broad and stable top-hat shape, minimizing photometric errors due to non-uniform pixel response, atmospheric seeing effects, imperfect guiding, and telescope-induced variable aberrations seen in defocusing. This PSF reshaping significantly increases the achievable dynamic range of our observations, increasing our observing efficiency and thus better averages over scintillation. Diffusers work in both collimated and converging beams. We present diffuser-assisted optical observations demonstrating 6216+2662^{+26}_{-16}ppm precision in 30 minute bins on a nearby bright star 16-Cygni A (V=5.95) using the ARC 3.5m telescope---within a factor of \sim2 of Kepler's photometric precision on the same star. We also show a transit of WASP-85-Ab (V=11.2) and TRES-3b (V=12.4), where the residuals bin down to 18041+66180^{+66}_{-41}ppm in 30 minute bins for WASP-85-Ab---a factor of \sim4 of the precision achieved by the K2 mission on this target---and to 101ppm for TRES-3b. In the NIR, where diffusers may provide even more significant improvements over the current state of the art, our preliminary tests have demonstrated 13736+64137^{+64}_{-36}ppm precision for a KS=10.8K_S =10.8 star on the 200" Hale Telescope. These photometric precisions match or surpass the expected photometric precisions of TESS for the same magnitude range. This technology is inexpensive, scalable, easily adaptable, and can have an important and immediate impact on the observations of transits and secondary eclipses of exoplanets.Comment: Accepted for publication in ApJ. 30 pages, 20 figure
    corecore