Deformation quantization of gerbes

This is the first in a series of articles devoted to deformation quantization of gerbes. Here we give basic definitions and interpret deformations of a given gerbe as Maurer-Cartan elements of a differential graded Lie algebra (DGLA). We classify all deformations of a given gerbe on a symplectic manifold, as well as provide a deformation-theoretic interpretation of the first Rozansky-Witten class.Comment: Revised versio

Higher Descent Data as a Homotopy Limit

We define the 2-groupoid of descent data assigned to a cosimplicial 2-groupoid and present it as the homotopy limit of the cosimplicial space gotten after applying the 2-nerve in each cosimplicial degree. This can be applied also to the case of $n$-groupoids thus providing an analogous presentation of "descent data" in higher dimensions.Comment: Appeared in JHR

A Method of Drusen Measurement Based on the Geometry of Fundus Reflectance

BACKGROUND: The hallmarks of age-related macular degeneration, the leading cause of blindness in the developed world, are the subretinal deposits known as drusen. Drusen identification and measurement play a key role in clinical studies of this disease. Current manual methods of drusen measurement are laborious and subjective. Our purpose was to expedite clinical research with an accurate, reliable digital method. METHODS: An interactive semi-automated procedure was developed to level the macular background reflectance for the purpose of morphometric analysis of drusen. 12 color fundus photographs of patients with age-related macular degeneration and drusen were analyzed. After digitizing the photographs, the underlying background pattern in the green channel was leveled by an algorithm based on the elliptically concentric geometry of the reflectance in the normal macula: the gray scale values of all structures within defined elliptical boundaries were raised sequentially until a uniform background was obtained. Segmentation of drusen and area measurements in the central and middle subfields (1000 μm and 3000 μm diameters) were performed by uniform thresholds. Two observers using this interactive semi-automated software measured each image digitally. The mean digital measurements were compared to independent stereo fundus gradings by two expert graders (stereo Grader 1 estimated the drusen percentage in each of the 24 regions as falling into one of four standard broad ranges; stereo Grader 2 estimated drusen percentages in 1% to 5% intervals). RESULTS: The mean digital area measurements had a median standard deviation of 1.9%. The mean digital area measurements agreed with stereo Grader 1 in 22/24 cases. The 95% limits of agreement between the mean digital area measurements and the more precise stereo gradings of Grader 2 were -6.4 % to +6.8 % in the central subfield and -6.0 % to +4.5 % in the middle subfield. The mean absolute differences between the digital and stereo gradings 2 were 2.8 +/- 3.4% in the central subfield and 2.2 +/- 2.7% in the middle subfield. CONCLUSIONS: Semi-automated, supervised drusen measurements may be done reproducibly and accurately with adaptations of commercial software. This technique for macular image analysis has potential for use in clinical research

Immigration Detention: Perspectives from Maine Law Students Working on the Ground at the Laredo Detention Center in Texas

Since 2017, students enrolled in the University of Maine School of Law Refugee and Human Rights Clinic have traveled to Laredo, Texas to participate in a program, sponsored and run by the law firm Jones Day in collaboration with Texas RioGrande Legal Aid, to provide representation for women in the Laredo Detention Center. Alongside Jones Day attorneys, the students conduct client intake interviews, draft memos detailing each woman’s experiences and any potential legal claims, and assist in the representation of clients. This article will provide a glimpse into the experiences of three Maine Law student attorneys during their time in Laredo, Texas, and will survey issues in the contemporary immigration landscape: first, an overview of the political climate surrounding the immigration debate, current immigration trends, and statistical figures; second, stories providing context for why people are seeking to immigrate to the U.S., and the persecution and challenges faced by immigrant women; third, the shortage of representation for immigrants, whether detained or non-detained; and finally, one of the most challenging and poignant issues encountered by student attorneys participating in the Laredo Project—the separation of immigrant mothers from their children

Simulation of gain stability of THGEM gas-avalanche particle detectors

Charging-up processes affecting gain stability in Thick Gas Electron Multipliers (THGEM) were studied with a dedicated simulation toolkit. Integrated with Garfield++, it provides an effective platform for systematic phenomenological studies of charging-up processes in MPGD detectors. We describe the simulation tool and the fine-tuning of the step-size required for the algorithm convergence, in relation to physical parameters. Simulation results of gain stability over time in THGEM detectors are presented, exploring the role of electrode-thickness and applied voltage on its evolution. The results show that the total amount of irradiated charge through electrode's hole needed for reaching gain stabilization is in the range of tens to hundreds of pC, depending on the detector geometry and operational voltage. These results are in agreement with experimental observations presented previously