The active optics software for the VST telescope

The VST (VLT Survey Telescope) active optics software must basically provide the analysis of the image coming from the wavefront sensor (a 10x10 subpupils Shack Hartmann device) and the calculation of primary mirror forces and secondary mirror displacements to correct the aberrations of the optical system, instrinsic or originated for thermal and gravity reasons. After the telescope commissioning the VST will be operated by ESO. In this framework, INAF-OAC staff was committed to design and realize the software in a VLT-compliant way. This will smoothen the integration, operation and maintenance of the telescope in the Paranal observatory

Galaxy evolution within the Kilo-Degree Survey

The ESO Public Kilo-Degree Survey (KiDS) is an optical wide-field imaging survey carried out with the VLT Survey Telescope and the OmegaCAM camera. KiDS will scan 1500 square degrees in four optical filters (u, g, r, i). Designed to be a weak lensing survey, it is ideal for galaxy evolution studies, thanks to the high spatial resolution of VST, the good seeing and the photometric depth. The surface photometry have provided with structural parameters (e.g. size and S\'ersic index), aperture and total magnitudes have been used to derive photometric redshifts from Machine learning methods and stellar masses/luminositites from stellar population synthesis. Our project aimed at investigating the evolution of the colour and structural properties of galaxies with mass and environment up to redshift $z \sim 0.5$ and more, to put constraints on galaxy evolution processes, as galaxy mergers.Comment: 4 pages, 2 figures, to appear on the refereed Proceeding of the "The Universe of Digital Sky Surveys" conference held at the INAF--OAC, Naples, on 25th-28th november 2014, to be published on Astrophysics and Space Science Proceedings, edited by Longo, Napolitano, Marconi, Paolillo, Iodic

The Atmospheric Dispersion Corrector Software for the VST

The effects of atmospheric differential refraction on astrophysical measurements are well known. In particular, as a ray of light passes through the atmosphere, its direction is altered by the effects of atmospheric refraction. The amount of this effect depends basically on the variation of the refractive index along the path of the ray. The real accuracy needed in the atmosphere model and in the calculation of the correction to be applied is of course, considerably worse, especially at large zenith angles. On the VLT Survey Telescope (VST) the use of an Atmospheric Dispersion Corrector (ADC) is foreseen at a wide zenith distance range. This paper describes the software design and implementation aspects regarding the analytical correction law discovered to correct the refraction effect during observations with VST

Efficacy and safety of GLP-1 receptor agonists as add-on to SGLT2 inhibitors in type 2 diabetes mellitus: A meta-analysis

GLP-1 receptor agonists (GLP-1RA) and SGLT2 inhibitors (SGLT2i) have been associated with improved glycemic control, body weight loss and favorable changes in cardiovascular risk factors and outcomes. We conducted a systematic review and meta-analysis to evaluate the effects of the addition of GLP-1RA to SGLT2i in patients with type 2 diabetes mellitus and inadequate glycemic control. Six databases were searched until March 2019. Randomized controlled trials (RCT) with a follow-up of at least 24 weeks reporting on HbA1c, body weight, systolic blood pressure, lipids, achievement of HbA1c < 7%, requirement of rescue therapy due to hyperglycemia and hypoglycemic events were selected. Four RCTs were included. Compared to SGLT2i, the GLP-1RA/SGLT2i combination was associated with greater reduction in HbA1c (−0.74%), body weight (−1.61 kg), and systolic blood pressure (−3.32 mmHg). A higher number of patients achieved HbA1c < 7% (RR = 2.15), with a lower requirement of rescue therapy (RR = 0.37) and similar incidence of hypoglycemia. Reductions in total and LDL cholesterol were found. The present review supports treatment intensification with GLP-1RA in uncontrolled type 2 diabetes on SGLT2i. This drug regimen could provide improved HbA1c control, together with enhanced weight loss and blood pressure and lipids control

Spatially Resolved Event-Driven 24 × 24 Pixels SPAD Imager with 100% Duty Cycle for Low Optical Power Quantum Entanglement Detection

Quantum microscopy requires efficient detectors able to identify temporal correlations among photons. Photon coincidences are usually detected by postprocessing their timestamps measured by means of time-To-digital converters (TDCs), through a time and power-consuming procedure, which impairs the overall system performance. In this article, we propose an innovative single-photon sensitive imager based on single-photon avalanche diodes (SPADs), able to signal coincident photon pairs along with their position through a TDC-free, event-driven architecture. The result is a highly efficient detector (25.8%) with a 100% duty cycle and minimized data throughput. The modular architecture and the 330 ns readout time, independent of pixel number, pave the way to large format imagers based on the same paradigm. The detector enabled quantum imaging at extremely low, microwatt-level optical pump powers, four orders of magnitude lower than previous experiments with similar optical setups

Unilateral inferior turbinate hypoplasia caused by a longstanding (approximately 35 yr) nasal foreign body.

We report the unusual case of a 44-year-old man who presented with a plastic foreign body that had been lodged in his right nasal cavity for approximately 35 years. Initial attempts to remove the object were unsuccessful; only after it was broken into several parts was removal achieved. Rigid nasal endoscopy and computed tomography revealed hypoplasia of the ipsilateral inferior turbinate