390 research outputs found
A Functional Random Effects Model for Flexible Assessment of Susceptibility in Longitudinal Designs
Ordinal Probit Functional Regression Models with Application to Computer-Use Behavior in Rhesus Monkeys
Research in functional regression has made great strides in expanding to
non-Gaussian functional outcomes, however the exploration of ordinal functional
outcomes remains limited. Motivated by a study of computer-use behavior in
rhesus macaques (\emph{Macaca mulatta}), we introduce the Ordinal Probit
Functional Regression Model or OPFRM to perform ordinal function-on-scalar
regression. The OPFRM is flexibly formulated to allow for the choice of
different basis functions including penalized B-splines, wavelets, and
O'Sullivan splines. We demonstrate the operating characteristics of the model
in simulation using a variety of underlying covariance patterns showing the
model performs reasonably well in estimation under multiple basis functions. We
also present and compare two approaches for conducting posterior inference
showing that joint credible intervals tend to out perform point-wise credible.
Finally, in application, we determine demographic factors associated with the
monkeys' computer use over the course of a year and provide a brief analysis of
the findings
Semiparametric Latent Variable Regression Models for Spatio-temporal Modeling of Mobile Source Particles in the Greater Boston Area
Traffic particle concentrations show considerable spatial variability within a metropolitan area. We consider latent variable semiparametric regression models for modeling the spatial and temporal variability of black carbon and elemental carbon concentrations in the greater Boston area. Measurements of these pollutants, which are markers of traffic particles, were obtained from several individual exposure studies conducted at specific household locations as well as 15 ambient monitoring sites in the city. The models allow for both flexible, nonlinear effects of covariates and for unexplained spatial and temporal variability in exposure. In addition, the different individual exposure studies recorded different surrogates of traffic particles, with some recording only outdoor concentrations of black or elemental carbon, some recording indoor concentrations of black carbon, and others recording both indoor and outdoor concentrations of black carbon. A joint model for outdoor and indoor exposure that specifies a spatially varying latent variable provides greater spatial coverage in the area of interest. We propose a penalised spline formation of the model that relates to generalised kringing of the latent traffic pollution variable and leads to a natural Bayesian Markov Chain Monte Carlo algorithm for model fitting. We propose methods that allow us to control the degress of freedom of the smoother in a Bayesian framework. Finally, we present results from an analysis that applies the model to data from summer and winter separatel
An Informative Bayesian Structural Equation Model to Assess Source-Specific Health Effects of Air Pollution
- …