15 research outputs found
A Comparative Study of Oral Candidal Carriage and Its Association with CD4 Count between HIV-Positive and Healthy Individuals
Association of genotypes with infection types and antifungal susceptibilities in Candida albicans
A comparative study on cell wall antigens and cell surface hydrophobicity in clinical isolates ofCandida albicans
Multicenter Brazilian Study of Oral Candida Species Isolated from Aids Patients
Oropharyngeal candidiasis continues to be considered the most common opportunistic disease in Aids patients. This study was designed to investigate species distribution, serotype and antifungal susceptibility profile among Candida spp. isolated from the oral cavity of Aids patients recruited from six Brazilian university centers. Oral swabs from 130 Aids patients were plated onto CHROMagar Candida medium and 142 isolates were recovered. Yeast isolates were identified by classical methods and serotyped using the Candida Check® system-Iatron. Antifungal susceptibility testing was performed according to the NCCLS microbroth assay. C. albicans was the most frequently isolated species (91%), and 70% of the isolates belonged to serotype A. We detected 12 episodes of co-infection (9%), including co-infection with both serotypes of C. albicans. Non-albicans species were isolated from 12 episodes, 50% of them exhibited DDS or resistance to azoles. Otherwise, only 8 out 130 isolates of C. albicans exhibited DDS or resistance to azoles. Brazilian Aids patients are infected mainly by C. albicans serotype A, most of them susceptible to all antifungal drugs
Human immunodeficiency virus infection: A review of the mode of infection, pathogenesis, disease course, and the general and clinical manifestations
Biofilms of Candida albicans serotypes A and B differ in their sensitivity to photodynamic therapy
Use of dual energy x-ray absorptiometry for noninvasive body composition measurements in clinically normal dogs
In vitro antifungal susceptibility of Candida spp. isolates from patients with chronic periodontitis and from control patients
Effects of a Phase III Cardiac Rehabilitation Program on Physical Status and Lipid Profiles in Elderly Patients With Coronary Artery Disease
Oral Candidiasis and Human-Immunodeficiency-Virus Infection
The association of oral candidiasis with the human immunodeficiency virus (HIV) infection has been known since the advent of the acquired immunodeficiency syndrome (AIDS) pandemic. Oral candidiasis is one of the earliest premonitory signs of HIV infection and its diagnosis may have grave prognostic implications for the eventual development of full blown AIDS. There is now an expanding body of data on novel clinical variants of this 'old' disease, its epidemiology in HIV seropositive individuals and, advances in its management, particularly with respect to the recently introduced bis-triazole antifungals. Current concepts pertaining to the epidemiology, clinical features, pathogenesis, laboratory diagnosis and management of oral candidiases in HIV infection are reviewed.link_to_subscribed_fulltex