2,045 research outputs found

    Phase space contraction and quantum operations

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    We give a criterion to differentiate between dissipative and diffusive quantum operations. It is based on the classical idea that dissipative processes contract volumes in phase space. We define a quantity that can be regarded as ``quantum phase space contraction rate'' and which is related to a fundamental property of quantum channels: non-unitality. We relate it to other properties of the channel and also show a simple example of dissipative noise composed with a chaotic map. The emergence of attaractor-like structures is displayed.Comment: 8 pages, 6 figures. Changes added according to refferee sugestions. (To appear in PRA

    Amyloid-β peptide 37, 38 and 40 individually and cooperatively inhibit amyloid-β 42 aggregation

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    The pathology of Alzheimer's disease is connected to the aggregation of β-amyloid (Aβ) peptide, which in vivo exists as a number of length-variants. Truncations and extensions are found at both the N- and C-termini, relative to the most commonly studied 40- and 42-residue alloforms. Here, we investigate the aggregation of two physiologically abundant alloforms, Aβ37 and Aβ38, as pure peptides and in mixtures with Aβ40 and Aβ42. A variety of molar ratios were applied in quaternary mixtures to investigate whether a certain ratio is maximally inhibiting of the more toxic alloform Aβ42. Through kinetic analysis, we show that both Aβ37 and Aβ38 self-assemble through an autocatalytic secondary nucleation reaction to form fibrillar β-sheet-rich aggregates, albeit on a longer timescale than Aβ40 or Aβ42. Additionally, we show that the shorter alloforms co-aggregate with Aβ40, affecting both the kinetics of aggregation and the resulting fibrillar ultrastructure. In contrast, neither Aβ37 nor Aβ38 forms co-aggregates with Aβ42; however, both short alloforms reduce the rate of Aβ42 aggregation in a concentration-dependent manner. Finally, we show that the aggregation of Aβ42 is more significantly impeded by a combination of Aβ37, Aβ38, and Aβ40 than by any of these alloforms independently. These results demonstrate that the aggregation of any given Aβ alloform is significantly perturbed by the presence of other alloforms, particularly in heterogeneous mixtures, such as is found in the extracellular fluid of the brain. This journal i

    Design and practical deployment of a network-centric remotely piloted aircraft system

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    Remotely piloted aircraft systems (RPASs) are gaining more are more relevance during the last decade since more applications are being enabled by lighter planes with increasing autonomy, higher ceilings, and more powerful transmission technologies. The integration of the RPAS as part of network-centric warfare would be a very important milestone to achieve because of the huge amount of information and capabilities that all these aircrafts can incorporate into the global scheme. This integration is easier for handheld (short-range) RPASs since their communications are typically based on digital transmission like WiFi or WiMAX, but it may not be as obvious for bigger RPASs (long-range, e.g., tactical or medium/high altitude systems) because their line of sight communications are frequently based on analog transmissions. This implies indirect integration into network-centric warfare by means of the ground control station (satellite communications, when available, may suffer notorious delay for certain applications). This article presents a recent practical experience, including flight test campaigns, deploying an all- IP communication architecture into one of the most relevant Spanish tactical RPASs, the SIVA, used by both the Spanish Army and the Spanish Air Force for the last 10 years. This deployment enables cost-effective integration of this RPAS (and its natural successor, the MILANO, a medium- altitude RPAS) into the network-centric warfare by means of direct TCP/IP transmissions over a long-range digital line of sight channel combined with satellite communications for beyond line of sight operations. The proposed design includes network-level security over the radio interfaces, automatic data link selection, support of remote video terminals, and access connectivity toward external IPv6 networks.This work has been partially granted by the Spanish Ministry of Defense through the DRONE project (DN8644-COINCIDENTE-10032110042). The authors want to acknowledge the INTA and Erzia Technologies S.L. personnel who participated in the DRONE project for fruitful collaboration and excellent work. The work of Francisco Valera has been partially funded by the Spanish Government through the MINECO eeCONTENT Project (TEC2011-29688-C02-02)

    Boosting mobility performance with multi-path TCP

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    Proceeding of: Future Network & Mobile Summit 2010, 16 - 18 June 2010, Florence, ItalyFourth Generation mobile devices incorporate multiple interfaces with diverse access technologies. The current Mobile IP protocol fails to support the enhanced fault tolerance capabilities that are enabled by the availability of multiple interfaces. In particular, established Mobile IP communications cannot be preserved through outages affecting the Home Address. In this paper we describe an architecture for mobile host multihoming that enables transport layer survivability through multiple failure modes. The proposed approach relies on the cooperation between Mobile IP and Multi-Path TCP and aims to fully support multihoming and extend roaming capabilities of mobile devices.This research was supported by Trilogy (http://www.trilogy-project.org), a research project (ICT-216372) partially funded by the European Community under its Seventh Framework Programme.European Community's Seventh Framework ProgramNo publicad

    Evanescent wave approach to diffractive phenomena in convex billiards with corners

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    What we are going to call in this paper "diffractive phenomena" in billiards is far from being deeply understood. These are sorts of singularities that, for example, some kind of corners introduce in the energy eigenfunctions. In this paper we use the well-known scaling quantization procedure to study them. We show how the scaling method can be applied to convex billiards with corners, taking into account the strong diffraction at them and the techniques needed to solve their Helmholtz equation. As an example we study a classically pseudointegrable billiard, the truncated triangle. Then we focus our attention on the spectral behavior. A numerical study of the statistical properties of high-lying energy levels is carried out. It is found that all computed statistical quantities are roughly described by the so-called semi-Poisson statistics, but it is not clear whether the semi-Poisson statistics is the correct one in the semiclassical limit.Comment: 7 pages, 8 figure

    Distribution of resonances in the quantum open baker map

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    We study relevant features of the spectrum of the quantum open baker map. The opening consists of a cut along the momentum pp direction of the 2-torus phase space, modelling an open chaotic cavity. We study briefly the classical forward trapped set and analyze the corresponding quantum nonunitary evolution operator. The distribution of eigenvalues depends strongly on the location of the escape region with respect to the central discontinuity of this map. This introduces new ingredients to the association among the classical escape and quantum decay rates. Finally, we could verify that the validity of the fractal Weyl law holds in all cases.Comment: 6 pages, 7 figures, accepted for publication in Phys. Rev.

    Quantum Holographic Encoding in a Two-dimensional Electron Gas

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    The advent of bottom-up atomic manipulation heralded a new horizon for attainable information density, as it allowed a bit of information to be represented by a single atom. The discrete spacing between atoms in condensed matter has thus set a rigid limit on the maximum possible information density. While modern technologies are still far from this scale, all theoretical downscaling of devices terminates at this spatial limit. Here, however, we break this barrier with electronic quantum encoding scaled to subatomic densities. We use atomic manipulation to first construct open nanostructures--"molecular holograms"--which in turn concentrate information into a medium free of lattice constraints: the quantum states of a two-dimensional degenerate Fermi gas of electrons. The information embedded in the holograms is transcoded at even smaller length scales into an atomically uniform area of a copper surface, where it is densely projected into both two spatial degrees of freedom and a third holographic dimension mapped to energy. In analogy to optical volume holography, this requires precise amplitude and phase engineering of electron wavefunctions to assemble pages of information volumetrically. This data is read out by mapping the energy-resolved electron density of states with a scanning tunnelling microscope. As the projection and readout are both extremely near-field, and because we use native quantum states rather than an external beam, we are not limited by lensing or collimation and can create electronically projected objects with features as small as ~0.3 nm. These techniques reach unprecedented densities exceeding 20 bits/nm2 and place tens of bits into a single fermionic state.Comment: Published online 25 January 2009 in Nature Nanotechnology; 12 page manuscript (including 4 figures) + 2 page supplement (including 1 figure); supplementary movie available at http://mota.stanford.ed

    Salerno's model of DNA reanalysed: could solitons have biological significance?

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    We investigate the sequence-dependent behaviour of localised excitations in a toy, nonlinear model of DNA base-pair opening originally proposed by Salerno. Specifically we ask whether ``breather'' solitons could play a role in the facilitated location of promoters by RNA polymerase. In an effective potential formalism, we find excellent correlation between potential minima and {\em Escherichia coli} promoter recognition sites in the T7 bacteriophage genome. Evidence for a similar relationship between phage promoters and downstream coding regions is found and alternative reasons for links between AT richness and transcriptionally-significant sites are discussed. Consideration of the soliton energy of translocation provides a novel dynamical picture of sliding: steep potential gradients correspond to deterministic motion, while ``flat'' regions, corresponding to homogeneous AT or GC content, are governed by random, thermal motion. Finally we demonstrate an interesting equivalence between planar, breather solitons and the helical motion of a sliding protein ``particle'' about a bent DNA axis.Comment: Latex file 20 pages, 5 figures. Manuscript of paper to appear in J. Biol. Phys., accepted 02/09/0

    ISOPHOT - Photometric Calibration of Point Sources

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    All observations by the aperture photometer (PHT-P) and the far-infrared (FIR) camera section (PHT-C) of ISOPHOT included reference measurements against stable internal fine calibration sources (FCS) to correct for temporal drifts in detector responsivities. The FCSs were absolutely calibrated in-orbit against stars, asteroids and planets, covering wavelengths from 3.2 to 240 micron. We present the calibration concept for point sources within a flux-range from 60 mJy up to 4500 Jy for staring and raster observations in standard configurations and discuss the requisite measurements and the uncertainties involved. In this process we correct for instrumental effects like nonlinearities, signal transients, time variable dark current, misalignments and diffraction effects. A set of formulae is developed that describes the calibration from signal-level to flux densities. The scatter of 10 to 20 % of the individual data points around the derived calibration relations is a measure of the consistency and typical accuracy of the calibration. The reproducibility over longer periods of time is better than 10 %. The calibration tables and algorithms have been implemented in the final versions of the software for offline processing and interactive analysis
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