29 research outputs found
MICROBIAL BASED CHLORINATED ETHENE DESTRUCTION
A mixed culture of Dehalococcoides species is provided that has an ability to catalyze the complete dechlorination of polychlorinated ethenes such as PCE, TCE, cDCE, 1,1-DCE and vinyl chloride as well as halogenated ethanes such as 1,2-DCA and EDB. The mixed culture demonstrates the ability to achieve dechlorination even in the presence of high source concentrations of chlorinated ethenes
Influence of pirfenidone on airway hyperresponsiveness and inflammation in a Brown-Norway rat model of asthma
Pirfenidone was administered to sensitized Brown Norway rats prior to a series of ovalbumin challenges. Airway hyperresponsiveness, inflammatory cell infiltration, mucin and collagen content, and the degree of epithelium and smooth muscle staining for TGF-β were examined in control, sensitized, and sensitized/challenged rats fed a normal diet or pirfenidone diet. Pirfenidone had no effect on airway hyperresponsiveness, but reduced distal bronchiolar cell infiltration and proximal and distal mucin content. Statistical analysis showed that the control group and sensitized/challenged pirfenidone diet group TGF-β staining intensity scores were not significantly different from isotype controls, but that the staining intensity scores for the sensitized/challenged normal diet group was significantly different from isotype controls. These results suggest that pirfenidone treatment is effective in reducing some of the components of acute inflammation induced by allergen challenge. © 2006 Elsevier Ltd. All rights reserved
Nonprofit and for‐profit developers of subsidized rental housing: Comparative attributes and collaborative opportunities
Assessment of Regional Variation in Streamflow Responses to Urbanization and the Persistence of Physiography
Aquatic ecosystems
are sensitive to the modification of hydrologic
regimes, experiencing declines in stream health as the streamflow
regime is altered during urbanization. This study uses streamflow
records to quantify the type and magnitude of hydrologic changes across
urbanization gradients in nine U.S. cities (Atlanta, GA, Baltimore,
MD, Boston, MA, Detroit, MI, Raleigh, NC, St. Paul, MN, Pittsburgh,
PA, Phoenix, AZ, and Portland, OR) in two physiographic settings.
Results indicate similar development trajectories among urbanization
gradients, but heterogeneity in the type and magnitude of hydrologic
responses to this apparently uniform urban pattern. Similar urban
patterns did not confer similar hydrologic function. Study watersheds
in landscapes with level slopes and high soil permeability had less
frequent high-flow events, longer high-flow durations, lower flashiness
response, and lower flow maxima compared to similarly developed watersheds
in landscape with steep slopes and low soil permeability. Our results
suggest that physical characteristics associated with level topography
and high water-storage capacity buffer the severity of hydrologic
changes associated with urbanization. Urbanization overlain upon a
diverse set of physical templates creates multiple pathways toward
hydrologic impairment; therefore, we caution against the use of the
urban homogenization framework in examining geophysically dominated
processes