1,197 research outputs found

    The Structure of the Nucleon: Elastic Electromagnetic Form Factors

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    Precise proton and neutron form factor measurements at Jefferson Lab, using spin observables, have recently made a significant contribution to the unraveling of the internal structure of the nucleon. Accurate experimental measurements of the nucleon form factors are a test-bed for understanding how the nucleon's static properties and dynamical behavior emerge from QCD, the theory of the strong interactions between quarks. There has been enormous theoretical progress, since the publication of the Jefferson Lab proton form factor ratio data, aiming at reevaluating the picture of the nucleon. We will review the experimental and theoretical developments in this field and discuss the outlook for the future.Comment: arXiv admin note: text overlap with arXiv:1301.0905, arXiv:hep-ph/0609004, arXiv:1411.6908 by other author

    The mysterious steps in carcinogenesis: addendum

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    Arsenite-Induced Alterations of DNA Photodamage Repair and Apoptosis After Solar-Simulation UVR in Mouse Keratinocytes in Vitro

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    Our laboratory has shown that arsenite markedly increased the cancer rate caused by solar-simulation ultraviolet radiation (UVR) in the hairless mouse skin model. In the present study, we investigated how arsenite affected DNA photodamage repair and apoptosis after solar-simulation UVR in the mouse keratinocyte cell line 291.03C. The keratinocytes were treated with different concentrations of sodium arsenite (0.0, 2.5, 5.0 μM) for 24 hr and then were immediately irradiated with a single dose of 0.30 kJ/m(2) UVR. At 24 hr after UVR, DNA photoproducts [cyclobutane pyrimidine dimers (CPDs) and 6–4 photoproducts (6-4PPs)] and apoptosis were measured using the enzyme-linked immunosorbent assay and the two-color TUNEL (terminal deoxynucleotide transferase dUTP nick end labeling) assay, respectively. The results showed that arsenite reduced the repair rate of 6-4PPs by about a factor of 2 at 5.0 μM and had no effect at 2.5 μM. UVR-induced apoptosis at 24 hr was decreased by 22.64% at 2.5 μM arsenite and by 61.90% at 5.0 μM arsenite. Arsenite decreased the UVR-induced caspase-3/7 activity in parallel with the inhibition of apoptosis. Colony survival assays of the 291.03C cells demonstrate a median lethal concentration (LC(50)) of arsenite of 0.9 μM and a median lethal dose (LD(50)) of UVR of 0.05 kJ/m(2). If the present results are applicable in vivo, inhibition of UVR-induced apoptosis may contribute to arsenite’s enhancement of UVR-induced skin carcinogenesis

    Managing the Transition from SNMP to NETCONF: Comparing Dual-Stack and Protocol Gateway Hybrid Approaches

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    As industries become increasingly automated and stressed to seek business advantages, they often have operational constraints that make modernization and security more challenging. Constraints exist such as low operating budgets, long operational lifetimes and infeasible network/device upgrade/modification paths. In order to bypass these constraints with minimal risk of disruption and perform ``no harm'', network administrators have come to rely on using dual-stack approaches, which allow legacy protocols to co-exist with modern ones. For example, if SNMP is required for managing legacy devices, and a newer protocol (NETCONF) is required for modern devices, then administrators simply modify firewall Access Control Lists (ACLs) to allow passage of both protocols. In today's networks, firewalls are ubiquitous, relatively inexpensive, and able to support multiple protocols (hence dual-stack) while providing network security. While investigating securing legacy devices in heterogeneous networks, it was determined that dual-stack firewall approaches do not provide adequate protection beyond layer three filtering of the IP stack. Therefore, the NETCONF/SNMP Protocol Gateway hybrid (NSPG) was developed as an alternative in environments where security is necessary, but legacy devices are infeasible to upgrade, replace, and modify. The NSPG allows network administrators to utilize only a single modern protocol (NETCONF) instead of both NETCONF and SNMP, and enforce additional security controls without modifying existing deployments. It has been demonstrated that legacy devices can be securely managed in a protocol-agnostic manner using low-cost commodity hardware (e.g., the RaspberryPi platform) with administrator-derived XML-based configuration policies

    Nanocavity enhanced photon coherence of solid-state quantum emitters operating up to 30 K

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    Solid-state emitters such as epitaxial quantum dots have emerged as a leading platform for efficient, on-demand sources of indistinguishable photons, a key resource for many optical quantum technologies. To maximise performance, these sources normally operate at liquid helium temperatures (4 K{\sim}4~\mathrm{K}), introducing significant size, weight and power requirements that can be impractical for proposed applications. Here we experimentally resolve the two distinct temperature-dependent phonon interactions that degrade indistinguishability, allowing us to demonstrate that coupling to a photonic nanocavity can greatly improve photon coherence at elevated temperatures up to 30 K30~\mathrm{K} that are compatible with compact cryocoolers. We derive a polaron model that fully captures the temperature-dependent influence of phonons observed in our experiments, providing predictive power to further increase the indistinguishability and operating temperature of future devices through optimised cavity parameters

    Electroexcitation of the P33(1232), P11(1440), D13(1520), S11(1535) at Q^2=0.4 and 0.65(GeV/c)^2

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    Using two approaches: dispersion relations and isobar model, we have analyzed recent high precision CLAS data on cross sections of \pi^0, \pi^+, and \eta electroproduction on protons, and the longitudinally polarized electron beam asymmetry for p(\vec{e},e'p)\pi^0 and p(\vec{e},e'n)\pi^+. The contributions of the resonances P33(1232), P11(1440), D13(1520), S11(1535) to \pi electroproduction and S11(1535) to \eta electroproduction are found. The results obtained in the two approaches are in good agreement with each other. There is also good agreement between amplitudes of the \gamma^* N \to S11(1535) transition found in \pi and \eta electroproduction. For the first time accurate results are obtained for the longitudinal amplitudes of the P11(1440), D13(1520) and S11(1535) electroexcitation on protons.Comment: 9 pages, 9 figure
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