111 research outputs found

    Exploring weight loss services in primary care and staff views on using a web-based programme

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    Although primary care staff felt they should deliver weight loss services, low levels of faith in the efficacy of current treatments resulted in provision of under-resourced and 'ad hoc' services. Integration of a web-based weight loss programme that promotes service evaluation and provides a cost-effective option for supporting patients may encourage practices to invest more in weight management service

    Effect of the National Resident Assessment Instrument on Selected Health Conditions and Problems

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/111253/1/j.1532-5415.1997.tb02972.x.pd

    Changes in Hospitalization Associated with Introducing the Resident Assessment Instrument

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/111190/1/j.1532-5415.1997.tb02973.x.pd

    A Draft of the Genome of the Gulf Coast tick, \u3ci\u3eAmblyomma maculatum\u3c/i\u3e

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    The Gulf Coast tick, Amblyomma maculatum, inhabits the Southeastern states of the USA bordering the Gulf of Mexico, Mexico, and other Central and South American countries. More recently, its U.S. range has extended West to Arizona and Northeast to New York state and Connecticut. It is a vector of Rickettsia parkeri and Hepatozoon americanum. This tick species has become a model to study tick/Rickettsia interactions. To increase our knowledge of the basic biology of A. maculatum we report here a draft genome of this tick and an extensive functional classification of its proteome. The DNA from a single male tick was used as a genomic source, and a 10X genomics protocol determined 28,460 scaffolds having equal or more than 10 Kb, totaling 1.98 Gb. The N50 scaffold size was 19,849 Kb. The BRAKER pipeline was used to find the protein-coding gene boundaries on the assembled A. maculatum genome, discovering 237,921 CDS. After trimming and classifying the transposable elements, bacterial contaminants, and truncated genes, a set of 25,702 were annotated and classified as the core gene products. A BUSCO analysis revealed 83.4% complete BUSCOs. A hyperlinked spreadsheet is provided, allowing browsing of the individual gene products and their matches to several databases

    ALMA Resolves the Nuclear Disks of Arp 220

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    We present 90 mas (37 pc) resolution ALMA imaging of Arp 220 in the CO (1-0) line and continuum at λ =2.6 mm. The internal gas distribution and kinematics of both galactic nuclei are well resolved for the first time. In the west nucleus, the major gas and dust emission extends out to 0[fraction of arcsecond symbol]2 radius (74 pc); the central resolution element shows a strong peak in the dust emission but a factor of 3 dip in the CO line emission. In this nucleus, the dust is apparently optically thick (τ [subscript 2.6mm ~ 1]) at λ = 2.6mm with a dust brightness temperature of ~147 K. The column of interstellar matter at this nucleus is N[subscript H2] ≄ 2 x 10 [superscript 26] cm[superscript −2], corresponding to ~900 gr cm[superscript −2]. The east nucleus is more elongated with radial extent 0[fraction of arcsecond symbol]3 or ~111 pc. The derived kinematics of the nuclear disks provide a good fit to the line profiles, yielding the emissivity distributions, the rotation curves, and velocity dispersions. In the west nucleus, there is evidence of a central Keplerian component requiring a central mass of 8 × 10[superscript 8]M [subscript ⊙]. The intrinsic widths of the emission lines are a ΔΜ(FWHM})=250 (west) and 120 (east) km s[superscript −1]. Given the very short dissipation timescales for turbulence (≀ [superscript 5] years), we suggest that the line widths may be due to semicoherent motions within the nuclear disks. The symmetry of the nuclear disk structures is impressive, implying the merger timescale is significantly longer than the rotation period of the disks

    Author Correction: Discovery of 42 genome-wide significant loci associated with dyslexia

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    Correction to: Nature Genetics https://doi.org/10.1038/s41588-022-01192-y. Published online 20 October 2022. In the version of this article originally published, a paragraph was omitted in the Methods section, reading “Genomic control. Top SNPs are reported from the more conservative GWAS results adjusted for genomic control (Fig. 1, Extended Data Figs. 1–4, and Supplementary Tables 1, 2, 9 and 10), whereas downstream analyses (including gene-set analysis, enrichment and heritability partitioning, genetic correlations, polygenic prediction, candidate gene replication) are based on GWAS results without genomic control.” The paragraph has now been included in the HTML and PDF versions of the article
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