2 research outputs found
Global disparities in SARS-CoV-2 genomic surveillance
Genomic sequencing is essential to track the evolution and spread of SARS-CoV-2, optimize molecular tests, treatments, vaccines, and guide public health responses. To investigate the global SARS-CoV-2 genomic surveillance, we used sequences shared via GISAID to estimate the impact of sequencing intensity and turnaround times (TAT) on variant detection in 189 countries. In two years of pandemic, 78% of high income countries (HICs) sequenced >0.5% of their COVID-19 cases, while 42% of low (LICs) and middle income countries (MICs) reached that mark. Around 25% of the genomes from HICs were submitted within 21 days, a pattern observed in 5% of the genomes from LICs and MICs. We found that sequencing around 0.5% of the cases, with a TAT <21 days, could provide a benchmark for SARS-CoV-2 genomic surveillance. Socioeconomic inequalities undermine the global pandemic preparedness, and efforts must be made to support LICs and MICs improve their local sequencing capacity