26,916 research outputs found
Competing Explanations of U.S. Defense Industry Consolidation in the 1990s and Their Policy Implications
Was the consolidation of defense industry in the 1990s driven by U.S. Department of Defense (DOD) directives, or was it driven instead by the same forces that drove consolidation in many other sectors of the U.S. economy in the 1990s? To better understand the roles of DOD policy and economy-wide forces in shaping the U.S. defense industry, we test for structural breaks in defense industry and spending data and compare our findings to those relating to other sectors and the general economy. We identify structural breaks in the defense-related data in the early 1980s and throughout the 1990s, roughly consistent with changes in the U.S. economy, including broader merger trends. Overall, our results are more consistent with the view that economy-wide factors drove defense industry consolidation, largely independent of the DOD policy changes that occurred early in the 1990s.
Draft Genome Sequence of Rhizobium rhizogenes Strain ATCC 15834.
Here, we present the draft genome of Rhizobium rhizogenes strain ATCC 15834. The genome contains 7,070,307 bp in 43 scaffolds. R. rhizogenes, also known as Agrobacterium rhizogenes, is a plant pathogen that causes hairy root disease. This hairy root induction has been used in biotechnology for the generation of transgenic root cultures
Numerical investigation of black hole interiors
Gravitational perturbations which are present in any realistic stellar
collapse to a black hole, die off in the exterior of the hole, but experience
an infinite blueshift in the interior. This is believed to lead to a slowly
contracting lightlike scalar curvature singularity, characterized by a
divergence of the hole's (quasi-local) mass function along the inner horizon.
The region near the inner horizon is described to great accuracy by a plane
wave spacetime. While Einstein's equations for this metric are still too
complicated to be solved in closed form it is relatively simple to integrate
them numerically.
We find for generic regular initial data the predicted mass inflation type
null singularity, rather than a spacelike singularity. It thus seems that mass
inflation indeed represents a generic self-consistent picture of the black hole
interior.Comment: 6 pages LaTeX, 3 eps figure
Nuclear effects in the proton-deuteron Drell-Yan process
We compute the nuclear corrections to the proton-deuteron Drell-Yan cross
section for inclusive dilepton production, which, when combined with the
proton-proton cross section, is used to determine the flavor asymmetry in the
proton sea, dbar - ubar. In addition to nuclear smearing corrections that are
known to be important at large values of the nucleon's parton momentum fraction
x_N, we also consider dynamical off-shell nucleon corrections associated with
the modifications of the bound nucleon structure inside the deuteron, which we
find to be significant at intermediate and large x_N values. We also provide
estimates of the nuclear corrections at kinematics corresponding to existing
and planned Drell-Yan experiments at Fermilab and J-PARC which aim to determine
the dbar/ubar ratio for x < 0.6.Comment: 26 pages, 6 figures; Fig. 2 and typos corrected, published versio
Cosmic Censorship: As Strong As Ever
Spacetimes which have been considered counter-examples to strong cosmic
censorship are revisited. We demonstrate the classical instability of the
Cauchy horizon inside charged black holes embedded in de Sitter spacetime for
all values of the physical parameters. The relevant modes which maintain the
instability, in the regime which was previously considered stable, originate as
outgoing modes near to the black hole event horizon. This same mechanism is
also relevant for the instability of Cauchy horizons in other proposed
counter-examples of strong cosmic censorship.Comment: 4 pages RevTeX style, 1 figure included using epsfi
Shellability of noncrossing partition lattices
We give a case-free proof that the lattice of noncrossing partitions
associated to any finite real reflection group is EL-shellable. Shellability of
these lattices was open for the groups of type and those of exceptional
type and rank at least three.Comment: 10 page
Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury.
PurposeDeposition of fibrin in the alveolar space is a hallmark of acute lung injury (ALI). Plasminogen activator inhibitor-1 (PAI-1) is an antifibrinolytic agent that is activated during inflammation. Increased plasma and pulmonary edema fluid levels of PAI-1 are associated with increased mortality in adults with ALI. This relationship has not been examined in children. The objective of this study was to test whether increased plasma PAI-1 levels are associated with worse clinical outcomes in pediatric patients with ALI.Design/methodsWe measured plasma PAI-1 levels on the first day of ALI among 94 pediatric patients enrolled in two separate prospective, multicenter investigations and followed them for clinical outcomes. All patients met American European Consensus Conference criteria for ALI.ResultsA total of 94 patients were included. The median age was 3.2 years (range 16 days-18 years), the PaO(2)/F(i)O(2) was 141 +/- 72 (mean +/- SD), and overall mortality was 14/94 (15%). PAI-1 levels were significantly higher in nonsurvivors compared to survivors (P < 0.01). The adjusted odds of mortality doubled for every log increase in the level of plasma PAI-1 after adjustment for age and severity of illness.ConclusionsHigher PAI-1 levels are associated with increased mortality and fewer ventilator-free days among pediatric patients with ALI. These findings suggest that impaired fibrinolysis may play a role in the pathogenesis of ALI in pediatric patients and suggest that PAI-1 may serve as a useful biomarker of prognosis in patients with ALI
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