26,916 research outputs found

    Competing Explanations of U.S. Defense Industry Consolidation in the 1990s and Their Policy Implications

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    Was the consolidation of defense industry in the 1990s driven by U.S. Department of Defense (DOD) directives, or was it driven instead by the same forces that drove consolidation in many other sectors of the U.S. economy in the 1990s? To better understand the roles of DOD policy and economy-wide forces in shaping the U.S. defense industry, we test for structural breaks in defense industry and spending data and compare our findings to those relating to other sectors and the general economy. We identify structural breaks in the defense-related data in the early 1980s and throughout the 1990s, roughly consistent with changes in the U.S. economy, including broader merger trends. Overall, our results are more consistent with the view that economy-wide factors drove defense industry consolidation, largely independent of the DOD policy changes that occurred early in the 1990s.

    Draft Genome Sequence of Rhizobium rhizogenes Strain ATCC 15834.

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    Here, we present the draft genome of Rhizobium rhizogenes strain ATCC 15834. The genome contains 7,070,307 bp in 43 scaffolds. R. rhizogenes, also known as Agrobacterium rhizogenes, is a plant pathogen that causes hairy root disease. This hairy root induction has been used in biotechnology for the generation of transgenic root cultures

    Numerical investigation of black hole interiors

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    Gravitational perturbations which are present in any realistic stellar collapse to a black hole, die off in the exterior of the hole, but experience an infinite blueshift in the interior. This is believed to lead to a slowly contracting lightlike scalar curvature singularity, characterized by a divergence of the hole's (quasi-local) mass function along the inner horizon. The region near the inner horizon is described to great accuracy by a plane wave spacetime. While Einstein's equations for this metric are still too complicated to be solved in closed form it is relatively simple to integrate them numerically. We find for generic regular initial data the predicted mass inflation type null singularity, rather than a spacelike singularity. It thus seems that mass inflation indeed represents a generic self-consistent picture of the black hole interior.Comment: 6 pages LaTeX, 3 eps figure

    Nuclear effects in the proton-deuteron Drell-Yan process

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    We compute the nuclear corrections to the proton-deuteron Drell-Yan cross section for inclusive dilepton production, which, when combined with the proton-proton cross section, is used to determine the flavor asymmetry in the proton sea, dbar - ubar. In addition to nuclear smearing corrections that are known to be important at large values of the nucleon's parton momentum fraction x_N, we also consider dynamical off-shell nucleon corrections associated with the modifications of the bound nucleon structure inside the deuteron, which we find to be significant at intermediate and large x_N values. We also provide estimates of the nuclear corrections at kinematics corresponding to existing and planned Drell-Yan experiments at Fermilab and J-PARC which aim to determine the dbar/ubar ratio for x < 0.6.Comment: 26 pages, 6 figures; Fig. 2 and typos corrected, published versio

    Cosmic Censorship: As Strong As Ever

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    Spacetimes which have been considered counter-examples to strong cosmic censorship are revisited. We demonstrate the classical instability of the Cauchy horizon inside charged black holes embedded in de Sitter spacetime for all values of the physical parameters. The relevant modes which maintain the instability, in the regime which was previously considered stable, originate as outgoing modes near to the black hole event horizon. This same mechanism is also relevant for the instability of Cauchy horizons in other proposed counter-examples of strong cosmic censorship.Comment: 4 pages RevTeX style, 1 figure included using epsfi

    Shellability of noncrossing partition lattices

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    We give a case-free proof that the lattice of noncrossing partitions associated to any finite real reflection group is EL-shellable. Shellability of these lattices was open for the groups of type DnD_n and those of exceptional type and rank at least three.Comment: 10 page

    Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury.

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    PurposeDeposition of fibrin in the alveolar space is a hallmark of acute lung injury (ALI). Plasminogen activator inhibitor-1 (PAI-1) is an antifibrinolytic agent that is activated during inflammation. Increased plasma and pulmonary edema fluid levels of PAI-1 are associated with increased mortality in adults with ALI. This relationship has not been examined in children. The objective of this study was to test whether increased plasma PAI-1 levels are associated with worse clinical outcomes in pediatric patients with ALI.Design/methodsWe measured plasma PAI-1 levels on the first day of ALI among 94 pediatric patients enrolled in two separate prospective, multicenter investigations and followed them for clinical outcomes. All patients met American European Consensus Conference criteria for ALI.ResultsA total of 94 patients were included. The median age was 3.2 years (range 16 days-18 years), the PaO(2)/F(i)O(2) was 141 +/- 72 (mean +/- SD), and overall mortality was 14/94 (15%). PAI-1 levels were significantly higher in nonsurvivors compared to survivors (P &lt; 0.01). The adjusted odds of mortality doubled for every log increase in the level of plasma PAI-1 after adjustment for age and severity of illness.ConclusionsHigher PAI-1 levels are associated with increased mortality and fewer ventilator-free days among pediatric patients with ALI. These findings suggest that impaired fibrinolysis may play a role in the pathogenesis of ALI in pediatric patients and suggest that PAI-1 may serve as a useful biomarker of prognosis in patients with ALI
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