Effects of synthesis parameters on the properties and photocatalytic activity of the magnetic catalyst TiO2/CoFe2O4 applied to selenium photoreduction

intake to human health. Heterogeneous photocatalysis can be successfully applied to remove selenium ions from water, but the photocatalyst recovery in the end of the process still needs improvement. The application of a magnetic photocatalyst (TiO2/CoFe2O4) in the Se(IV) photoreduction was investigated, with emphasis in the catalyst magnetic separation. The photocatalyst was synthetized via a simple sol-gel method and a central composite design was considered to evaluate the effects of titanium isopropoxide mass ratio used in the synthesis, calcination temperature and pH on Se(IV) reduction. Calcination temperature showed a strong influence in the photocatalytic activity, and the catalyst calcined at 381 ◦C presented the best performance. In the bests test, at pH 2.61, it was possible to remove >99% selenium after 2 min of exposure to radiation. Photocatalysts containing great amounts of rutile phase produced the lowest removal results. The TiO2/CoFe2O4 photocatalyst was magnetically separable, however its saturation magnetization (2.7 emu g 1) was considerably smaller than pure CoFe2O4 (84.6 emu g 1) and the photocatalyst magnetic separation from the aqueous medium was about 11 times slower in comparison to pure cobalt ferrite. The synthetized photocatalyst was able to satisfactorily photoreduce Se(IV) (96.5%) even after five cycles of photocatalysis

Pitfalls in the diagnosis of acoustic neuroma

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/71894/1/j.1365-2273.1984.tb01490.x.pd

Nitrogen fertilization affects yield and fruit quality in pear.

Made available in DSpace on 2019-09-18T00:43:14Z (GMT). No. of bitstreams: 1 GilbertoNavaHortscienceNitrogenfertilizationaffectsyieldand.pdf: 853244 bytes, checksum: 3f02f2dd6b4f23182ebe75319ad4b30b (MD5) Previous issue date: 2019bitstream/item/202086/1/Gilberto-Nava-Hortscience-Nitrogen-fertilization-affects-yield-and.pd

Structural and Functional Deficits in a Neuronal Calcium Sensor-1 Mutant Identified in a Case of Autistic Spectrum Disorder

Neuronal calcium sensor-1 (NCS-1) is a Ca2+ sensor protein that has been implicated in the regulation of various aspects of neuronal development and neurotransmission. It exerts its effects through interactions with a range of target proteins one of which is interleukin receptor accessory protein like-1 (IL1RAPL1) protein. Mutations in IL1RAPL1 have recently been associated with autism spectrum disorders and a missense mutation (R102Q) on NCS-1 has been found in one individual with autism. We have examined the effect of this mutation on the structure and function of NCS-1. From use of NMR spectroscopy, it appeared that the R102Q affected the structure of the protein particularly with an increase in the extent of conformational exchange in the C-terminus of the protein. Despite this change NCS-1(R102Q) did not show changes in its affinity for Ca2+ or binding to IL1RAPL1 and its intracellular localisation was unaffected. Assessment of NCS-1 dynamics indicated that it could rapidly cycle between cytosolic and membrane pools and that the cycling onto the plasma membrane was specifically changed in NCS-1(R102Q) with the loss of a Ca2+ -dependent component. From these data we speculate that impairment of the normal cycling of NCS-1 by the R102Q mutation could have subtle effects on neuronal signalling and physiology in the developing and adult brain

Networks of Neuronal Genes Affected by Common and Rare Variants in Autism Spectrum Disorders

Autism spectrum disorders (ASD) are neurodevelopmental disorders with phenotypic and genetic heterogeneity. Recent studies have reported rare and de novo mutations in ASD, but the allelic architecture of ASD remains unclear. To assess the role of common and rare variations in ASD, we constructed a gene co-expression network based on a widespread survey of gene expression in the human brain. We identified modules associated with specific cell types and processes. By integrating known rare mutations and the results of an ASD genome-wide association study (GWAS), we identified two neuronal modules that are perturbed by both rare and common variations. These modules contain highly connected genes that are involved in synaptic and neuronal plasticity and that are expressed in areas associated with learning and memory and sensory perception. The enrichment of common risk variants was replicated in two additional samples which include both simplex and multiplex families. An analysis of the combined contribution of common variants in the neuronal modules revealed a polygenic component to the risk of ASD. The results of this study point toward contribution of minor and major perturbations in the two sub-networks of neuronal genes to ASD risk