44 research outputs found

    High-dose glucocorticoid treatment of near-fatal Bocavirus lung infection results in rapid recovery

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    Human Bocavirus(HBoV) has to be considered as life-threatening pathogen inadults with atypical pneumonia. Pulsed high-dose glucocorticoid-treatmentmay be beneficial in patients suffering from severe pulmonary disease caused by HBoV or other viruses

    Acute myeloid leukemia: negative prognostic impact of early blast persistence can be in part overcome by a later remission prior to post-induction therapy

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    In acute myeloid leukemia, there is an ongoing debate on the prognostic value of the early bone marrow assessment in patients receiving intensive therapy. In this retrospective study, we analyzed the prognostic impact of the early response in 1,008 patients with newly diagnosed acute myeloid leukemia, who were treated at our institution with intensive chemotherapy followed by consolidation chemotherapy and/or allogeneic hematopoietic stem cell transplantation (HSCT). We found that early blast persistence has an independent negative prognostic impact on overall survival, eventfree survival and relapse-free survival. This negative prognostic impact may only be overcome in patients showing at least a partial remission at the early bone marrow assessment and who subsequently achieve blast clearance by additional induction chemotherapy prior to consolidation therapy with allogeneic HSCT. In accordance, we propose that the time slope of remission is an additional leukemia-related dynamic parameter that reflects chemosensitivity and thus may inform post-induction therapy decision-making. In addition to patient-related factors, European LeukemiaNet risk group, measurable residual disease monitoring and donor availability, this may particularly apply to European LeukemiaNet intermediate-risk patients, for whom a decision between consolidation chemotherapy and allogeneic HSCT remains challenging in many cases

    Die Jagdgenossenschaften

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    Habilitationsschrift--Halle.Bibliographical foot-notes.Mode of access: Internet

    Wydział Prawa Uniwersytetu Viadrina we Frankfurcie nad Odrą w latach 1506-1811

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    The university known as Viadrina, called after the Latin name for the Oder river, Viadrus, was founded at Frankfurt (Oder) in 1506 in response to the needs of a rapidly expanding territorial state in Brandenburg Land, which was in an urgent need of educated theologians, jurists, medics and teachers. The organisational structure of the school and the subjects taught in it met the university standards prevailing in the rest of Europe of those times. Students were recruited mainly from Brandenburg Land, although many came from Central and Eastern Europe as well, including a handful from Poland. Originally, the law faculty offered only reading in ecclesiastical law and Roman private law, but from the 17th century public law and criminal law had also been taught. The law graduates from Viadrina University were often raised to high ranks in politics, state administration and public law institutions. After the 30-year war, Viadrina boasted eminent professors of law who made valuable contributions to the revival of jurisprudence. In 1811 Viadrina was moved to Wroclaw (Breslau) and became an integral part of Wroclaw University.L’Université nommée « Viadrina » c’est ce qu’il provient du nom latin du fleuve Oder « Viadrus » avait été fondée à Francfort-sur-l’Oder à l’an 1506. La raison principale de la fondation de l’université dans cette ville était les besoins de l’État de Brandebourg dont le développement exigeait des juristes, des médecins et des théologiens bien instruits. L’organistaion de l’Université Viadrina ainsi que les programmes des études étaient conformes aux standarts appliqués en Europe. Les étudiants venaient en majorité de Brandebourg, mais aussi d’autres pays de l’Europe Centrale et Orientale. Parmi eux il y avait les nombreux étudiants polonais. Au départ, on ne donnaient que les cours du droit canonique et du droit romain privé. Dépuis le XVIIe siècle il y avait aussi des cours du droit public. Les diplomés de Viadrina réussissaient souvent atteindre les hautes positions dans leur vie professionnelle en politique, dans l’administration de l’État et dans la magistrature. Après la guèrre de Trent Ans le corp professoral de la Viadrina se composait des savants éminents qui apportaient leur concour au développement de la science européenne du droit. En 1811, la Viadrina a été transféré à Wrocław (Breslau) où elle faisait parti intégrale de l’Université locale.Viadrina – uniwersytet europejski od 1506 roku. Założenie uniwersytetu zwanego Viadrina (od Viadrus czyli Odra) we Frankfurcie nad Odrą w 1506 roku było elementem długiego procesu rozwojowego przebiegającego w całej Europie. Pierwsze uniwersytety powstały w pełni średniowiecza, około 1200 roku, w Europie Południowej i Zachodniej, m.in. w Bolonii, Paryżu i Oksfordzie. Pierwszym uniwersytetem w Świętym Cesarstwie Rzymskim Narodu Niemieckiego był założony w 1348 roku Uniwersytet Praski, natomiast pierwszy polski uniwersytet powstał w 1364 roku w Krakowie. W Niemczech wszystkie duże regiony otrzymywały stopniowo własne uniwersytety. W następstwie tego procesu książę elektor brandenburski Joachim I ufundował w 1506 roku Viadrinę we Frankfurcie nad Odrą. Do założenia uniwersytetu w Halle w 1694 roku był to jedyny uniwersytet w Brandenburgii
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