729 research outputs found
Plant pathogens provide clues to the potential origin of bat white-nose syndromePseudogymnoascus destructans
White-nose syndrome has killed millions of bats, yet both the origins and infection strategy of the causative fungus, Pseudogymnoascus destructans, remain elusive. We provide evidence for a novel hypothesis that P. destructans emerged from plant-associated fungi and retained invasion strategies affiliated with fungal pathogens of plants. We demonstrate that P. destructans invades bat skin in successive biotrophic and necrotrophic stages (hemibiotrophic infection), a mechanism previously only described in plant fungal pathogens. Further, the convergence of hyphae at hair follicles suggests nutrient tropism. Tropism, biotrophy, and necrotrophy are often associated with structures termed appressoria in plant fungal pathogens; the penetrating hyphae produced by P. destructans resemble appressoria. Finally, we conducted a phylogenomic analysis of a taxonomically diverse collection of fungi. Despite gaps in genetic sampling of prehistoric and contemporary fungal species, we estimate an 88% probability the ancestral state of the clade containing P. destructans was a plant-associated fungus
VLBI astrometry of PSR J2222-0137: a pulsar distance measured to 0.4% accuracy
The binary pulsar J2222-0137 is an enigmatic system containing a partially
recycled millisecond pulsar and a companion of unknown nature. Whilst the low
eccentricity of the system favors a white dwarf companion, an unusual double
neutron star system is also a possibility, and optical observations will be
able to distinguish between these possibilities. In order to allow the absolute
luminosity (or upper limit) of the companion object to be properly calibrated,
we undertook astrometric observations with the Very Long Baseline Array to
constrain the system distance via a measurement of annual geometric parallax.
With these observations, we measure the parallax of the J2222-0137 system to be
3.742 +0.013 -0.016 milliarcseconds, yielding a distance of 267.3 +1.2 -0.9 pc,
and measure the transverse velocity to be 57.1 +0.3 -0.2 km/s. Fixing these
parameters in the pulsar timing model made it possible to obtain a measurement
of Shapiro delay and hence the system inclination, which shows that the system
is nearly edge-on (sin i = 0.9985 +/- 0.0005). Furthermore, we were able to
detect the orbital motion of J2222-0137 in our VLBI observations and measure
the longitude of ascending node. The VLBI astrometry yields the most accurate
distance obtained for a radio pulsar to date, and is furthermore the most
accurate parallax for any radio source obtained at "low" radio frequencies
(below ~5 GHz, where the ionosphere dominates the error budget). Using the
astrometric results, we show the companion to J2222-0137 will be easily
detectable in deep optical observations if it is a white dwarf. Finally, we
discuss the implications of this measurement for future ultra-high-precision
astrometry, in particular in support of pulsar timing arrays.Comment: 22 pages, 7 figures, accepted for publication in Ap
Modeling Oyster Populations II. Adult Size and Reproductive Effort
A time-dependent model of energy flow in post-settlement oyster populations is used to examine the factors that influence adult size and reproductive effort in a particular habitat, Galveston Bay, Texas, and in habitats that extend from Laguna Madre, Texas to Chesapeake Bay. The simulated populations show that adult size and reproductive effort are determined by the allocation of net production to somatic or reproductive tissue development and the rate of food acquisition, both of which are temperature dependent. For similar food conditions, increased temperature reduces the allocation of net production to somatic tissue and increases the rate of food acquisition. This temperature effect, however, is mediated by changes in food supply. Within the Gulf of Mexico, oyster size declines from north to south because increased temperature decreases the allocation of net production to somatic growth. An increase in food supply generally results in increased size as more energy is used in somatic growth; however, at low latitudes, as food supply increases, adult size decreases because the allocation of more net production to reproduction outweighs the effect of increased rates of food acquisition. Variations in temperature and food supply affect reproductive effort more than adult size because the rate of energy flow through the oyster is higher in warmer months when most net production is allocated to reproduction and small changes in temperature substantially change the spawning season. The wide range of reproductive effort expected from small changes in temperature and food supply suggest that comparisons of adult size and reproductive effort between oyster populations can only be made within the context of a complete environmental analysis of food supply and associated physical parameters and an energy flow model
Discovery of Five New Pulsars in Archival Data
Reprocessing of the Parkes Multibeam Pulsar Survey has resulted in the
discovery of five previously unknown pulsars and several as-yet-unconfirmed
candidates. PSR J0922-52 has a period of 9.68 ms and a DM of 122.4 pc cm^-3.
PSR J1147-66 has a period of 3.72 ms and a DM of 133.8 pc cm^-3. PSR J1227-6208
has a period of 34.53 ms, a DM of 362.6 pc cm^-3, is in a 6.7 day binary orbit,
and was independently detected in an ongoing high-resolution Parkes survey by
Thornton et al. and also in independent processing by Einstein@Home volunteers.
PSR J1546-59 has a period of 7.80 ms and a DM of 168.3 pc cm^-3. PSR J1725-3853
is an isolated 4.79-ms pulsar with a DM of 158.2 pc cm^-3. These pulsars were
likely missed in earlier processing efforts due to their high DMs and short
periods and the large number of candidates that needed to be looked through.
These discoveries suggest that further pulsars are awaiting discovery in the
multibeam survey data.Comment: 12 pages, 2 figures, 2 tables, accepted to Ap
Discovery and Follow-up of Rotating Radio Transients with the Green Bank and LOFAR Telescopes
We have discovered 21 Rotating Radio Transients (RRATs) in data from the
Green Bank Telescope (GBT) 350-MHz Drift-scan and the Green Bank North
Celestial Cap pulsar surveys using a new candidate sifting algorithm. RRATs are
pulsars with sporadic emission that are detected through their bright single
pulses rather than Fourier domain searches. We have developed {\tt RRATtrap}, a
single-pulse sifting algorithm that can be integrated into pulsar survey data
analysis pipelines in order to find RRATs and Fast Radio Bursts. We have
conducted follow-up observations of our newly discovered sources at several
radio frequencies using the GBT and Low Frequency Array (LOFAR), yielding
improved positions and measurements of their periods, dispersion measures, and
burst rates, as well as phase-coherent timing solutions for four of them. The
new RRATs have dispersion measures (DMs) ranging from 15 to 97 pc cm,
periods of 240 ms to 3.4 s, and estimated burst rates of 20 to 400 pulses
hr at 350 MHz. We use this new sample of RRATs to perform statistical
comparisons between RRATs and canonical pulsars in order to shed light on the
relationship between the two populations. We find that the DM and spatial
distributions of the RRATs agree with those of the pulsars found in the same
survey. We find evidence that slower pulsars (i.e. ms) are
preferentially more likely to emit bright single pulses than are faster pulsars
( ms), although this conclusion is tentative. Our results are consistent
with the proposed link between RRATs, transient pulsars, and canonical pulsars
as sources in various parts of the pulse activity spectrum.Comment: 18 pages, 13 figures, 5 tables, published in Ap
Effects of Neonicotinoid Pesticide Exposure on Human Health: A Systematic Review.
BACKGROUND: Numerous studies have identified detectable levels of neonicotinoids (neonics) in the environment, adverse effects of neonics in many species including mammals, and pathways through which human exposure to neonics could occur, yet little is known about the human health effects of neonic exposure.
OBJECTIVE: This systematic review sought to identify human population studies on the health effects of neonics.
METHODS: Studies published in English between 2005 and 2015 were searched using PubMed, Scopus, and Web of Science databases. No restrictions were placed on the type of health outcome assessed. Risk of bias was assessed using guidance developed by the National Toxicology Program\u27s Office of Health Assessment and Translation.
RESULTS: Eight studies investigating the human health effects of exposure to neonics were identified. Four examined acute exposure: three neonic poisoning studies reported two fatalities (n=1280 cases) and an occupational exposure study of 19 forestry workers reported no adverse effects. Four general population studies reported associations between chronic neonic exposure and adverse developmental or neurological outcomes, including tetralogy of Fallot (AOR 2.4, 95% CI: 1.1-5.4), anencephaly (AOR 2.9, 95% CI: 1.0-8.2), autism spectrum disorder (AOR 1.3, 95% CrI: 0.78-2.2), and a symptom cluster including memory loss and finger tremor (OR 14, 95% CI: 3.5-57). Reported odds ratios were based on exposed compared to unexposed groups.
CONCLUSIONS: The studies conducted to date were limited in number with suggestive but methodologically weak findings related to chronic exposure. Given the wide-scale use of neonics, more needs to be known about their human health effects
A millisecond pulsar in a stellar triple system
Gravitationally bound three-body systems have been studied for hundreds of
years and are common in our Galaxy. They show complex orbital interactions,
which can constrain the compositions, masses, and interior structures of the
bodies and test theories of gravity, if sufficiently precise measurements are
available. A triple system containing a radio pulsar could provide such
measurements, but the only previously known such system, B1620-26 (with a
millisecond pulsar, a white dwarf, and a planetary-mass object in an orbit of
several decades), shows only weak interactions. Here we report precision timing
and multi-wavelength observations of PSR J0337+1715, a millisecond pulsar in a
hierarchical triple system with two other stars. Strong gravitational
interactions are apparent and provide the masses of the pulsar (1.4378(13)
Msun, where Msun is the solar mass and the parentheses contain the uncertainty
in the final decimal places) and the two white dwarf companions (0.19751(15)
Msun and 0.4101(3) Msun), as well as the inclinations of the orbits (both
approximately 39.2 degrees). The unexpectedly coplanar and nearly circular
orbits indicate a complex and exotic evolutionary past that differs from those
of known stellar systems. The gravitational field of the outer white dwarf
strongly accelerates the inner binary containing the neutron star, and the
system will thus provide an ideal laboratory in which to test the strong
equivalence principle of general relativity.Comment: 17 pages, 3 figures, 1 table. Published online by Nature on 5 Jan
2014. Extremely minor differences with published version may exis
The Green Bank Northern Celestial Cap Pulsar Survey - I: Survey Description, Data Analysis, and Initial Results
We describe an ongoing search for pulsars and dispersed pulses of radio
emission, such as those from rotating radio transients (RRATs) and fast radio
bursts (FRBs), at 350 MHz using the Green Bank Telescope. With the Green Bank
Ultimate Pulsar Processing Instrument, we record 100 MHz of bandwidth divided
into 4,096 channels every 81.92 . This survey will cover the entire sky
visible to the Green Bank Telescope (, or 82% of the sky)
and outside of the Galactic Plane will be sensitive enough to detect slow
pulsars and low dispersion measure (30 ) millisecond
pulsars (MSPs) with a 0.08 duty cycle down to 1.1 mJy. For pulsars with a
spectral index of 1.6, we will be 2.5 times more sensitive than previous and
ongoing surveys over much of our survey region. Here we describe the survey,
the data analysis pipeline, initial discovery parameters for 62 pulsars, and
timing solutions for 5 new pulsars. PSR J02145222 is an MSP in a long-period
(512 days) orbit and has an optical counterpart identified in archival data.
PSR J06365129 is an MSP in a very short-period (96 minutes) orbit with a
very low mass companion (8 ). PSR J06455158 is an isolated MSP
with a timing residual RMS of 500 ns and has been added to pulsar timing array
experiments. PSR J14347257 is an isolated, intermediate-period pulsar that
has been partially recycled. PSR J18164510 is an eclipsing MSP in a
short-period orbit (8.7 hours) and may have recently completed its spin-up
phase.Comment: 18 pages, 10 figures, 5 tables, accepted by Ap
Southern African HIV Clinicians Society guideline for the prevention, diagnosis and management of cryptococcal disease among HIV-infected persons: 2019 update.
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