Man vs. machine: Investigating the effects of adversarial system use on end-user behavior in automated deception detection interviews

Deception is an inevitable component of human interaction. Researchers and practitioners are developing information systems to aid in the detection of deceptive communication. Information systems are typically adopted by end users to aid in completing a goal or objective (e.g., increasing the efficiency of a business process). However, end-user interactions with deception detection systems (adversarial systems) are unique because the goals of the system and the user are orthogonal. Prior work investigating systems-based deception detection has focused on the identification of reliable deception indicators. This research extends extant work by looking at how users of deception detection systems alter their behavior in response to the presence of guilty knowledge, relevant stimuli, and system knowledge. An analysis of data collected during two laboratory experiments reveals that guilty knowledge, relevant stimuli, and system knowledge all lead to increased use of countermeasures. The implications and limitations of this research are discussed and avenues for future research are outline

The Uniform Basis Rules and Terminating Interests in Trusts Early

The resolution of income tax issues that may arise for trust beneficiaries who dispose of temporal interests in trusts remains relatively obscure. Additional issues exist for subsequent interest holders; the methods that the Code and Regulations prescribe for establishing, maintaining, and potentially recovering basis for successor owners of interests in a trust are not well developed.In some instances, the trust instrument creating a temporal interest will supply a suitable path for early termination and distribution of assets. In those cases, Sub-chapter J of the Code typically governs the transaction and provides that terminating the trust and distributing its assets be treated as nonrecognition events. However, one must look beyond the confines of Sub-chapter J when trust beneficiaries participate in the disposition without a settlor-provided power to do so. The Internal Revenue Service has consistently applied in letter rulings a different tax regime other than the income tax rules provided in Sub-chapter J of the Code; gain may be realized and recognized under section 1001, which often brings into play the uniform basis rules.The uniform basis rules reflect the concept that property acquired by gift or from a decedent has a single or uniform basis, whether multiple persons receive an interest in the property and whether directly or through a trust, and the individual interests have a basis that it is a proportional part of the uniform basis. The uniform basis rules of section 1001(e)(1) often deny the seller of a life or term interest in a trust any recovery of basis unless all interests in the trust are transferred to a third party for consideration. On the other the hand, the uniform basis rules permit a remainder beneficiary to recover basis in a sale, whether or not the life or term interest is also transferred. Besides these two basic rules, there are many nuances to the tax consequences of uniform basis rules and some interesting issues to evaluate when considering the sale of an interest in a trust, or the commutation or early termination of a trust, and how holders of transferred interests are treated for income tax purposes

Childhood maltreatment, psychological resources, and depressive symptoms in women with breast cancer.

Childhood maltreatment is associated with elevated risk for depression across the human lifespan. Identifying the pathways through which childhood maltreatment relates to depressive symptoms may elucidate intervention targets that have the potential to reduce the lifelong negative health sequelae of maltreatment exposure. In this cross-sectional study, 271 women with early-stage breast cancer were assessed after their diagnosis but before the start of adjuvant treatment (chemotherapy, radiation, endocrine therapy). Participants completed measures of childhood maltreatment exposure, psychological resources (optimism, mastery, self-esteem, mindfulness), and depressive symptoms. Using multiple mediation analyses, we examined which psychological resources uniquely mediated the relationship between childhood maltreatment and depressive symptoms. Exposure to maltreatment during childhood was robustly associated with lower psychological resources and elevated depressive symptoms. Further, lower optimism and mindfulness mediated the association between childhood maltreatment and elevated depressive symptoms. These results support existing theory that childhood maltreatment is associated with lower psychological resources, which partially explains elevated depressive symptoms in a sample of women facing breast cancer diagnosis and treatment. These findings warrant replication in populations facing other major life events and highlight the need for additional studies examining childhood maltreatment as a moderator of treatment outcomes

A Phenomenon Resembling Early Superhumps in a New SU UMa-Type Dwarf Nova with a 2-Hour Orbital Period

We investigate K2BS5, an optical transient that we identified in Campaign 13 of the Kepler/K2 archives by the "K2 Background Survey", and classify it as a new SU UMa-type dwarf nova. Using the light curve generated from Kepler's long-cadence observation mode, we analyze the dwarf nova during quiescence and superoutburst. Following 20 days of quiescence at the start of the observation, the system entered a superoutburst lasting 12 days, after which it experienced at least one rebrightening. K2BS5 clearly meets the criteria for an SU UMa star, but at the peak of the superoutburst, it also shows double-wave oscillations consistent with the spectroscopic orbital period, a phenomenon that closely resembles early superhumps in WZ Sge stars. While we do not classify K2BS5 as a WZ Sge system, we discuss how this phenomenon could complicate efforts to use the suspected detection of early superhumps to distinguish SU UMa-type dwarf novae from the recently recognized class of long-orbital-period WZ Sge systems.Comment: 11 pages, 7 figures. Accepted for publication in the Astronomical Journa

A Spectroscopic Survey of Faint Quasars in the SDSS Deep Stripe: I. Preliminary Results from the Co-added Catalog

In this paper we present the first results of a deep spectroscopic survey of faint quasars in the Sloan Digital Sky Survey (SDSS) Southern Survey, a deep survey carried out by repeatedly imaging a 270 deg^2 area. Quasar candidates were selected from the deep data with good completeness over 0<z<5, and 2 to 3 magnitudes fainter than the SDSS main survey. Spectroscopic follow-up was carried out on the 6.5m MMT with Hectospec. The preliminary sample of this SDSS faint quasar survey (hereafter SFQS) covers ~ 3.9 deg^2, contains 414 quasars, and reaches g=22.5. The overall selection efficiency is ~ 66% (~ 80% at g<21.5); the efficiency in the most difficult redshift range (2<z<3) is better than 40%. We use the 1/V_{a} method to derive a binned estimate of the quasar luminosity function (QLF) and model the QLF using maximum likelihood analysis. The best model fits confirm previous results showing that the QLF has steep slopes at the bright end and much flatter slopes (-1.25 at z<2.0 and -1.55 at z>2.0) at the faint end, indicating a break in the QLF slope. Using a luminosity-dependent density evolution model, we find that the quasar density at M_{g}<-22.5 peaks at z~2, which is later in cosmic time than the peak of z~2.5 found from surveys of more luminous objects. The SFQS QLF is consistent with the results of the 2dF QSO Redshift Survey, the SDSS, and the 2dF-SDSS LRG and QSO Survey, but probes fainter quasars. We plan to obtain more quasars from future observations and establish a complete faint quasar sample with more than 1000 objects over 10 deg^2.Comment: 25 pages, 13 figures, accepted for publication in A

Universal H1N1 influenza vaccine development

Immune responses to cross-conserved T cell epitopes in novel H1N1 influenza may explain reports of diminished influenza-like illnesses and confirmed infection among older adults, in the absence of cross-reactive humoral immunity, during the 2009 pandemic. These cross-conserved epitopes may prove useful for the development of a universal H1N1 influenza vaccine, therefore, we set out to identify and characterize cross-conserved H1N1 T cell epitopes. An immunoinformatic analysis was conducted using all available pandemic and pre-pandemic HA-H1 and NA-N1 sequences dating back to 1980. Using an approach that balances potential for immunogenicity with conservation, we derived 13 HA and four NA immunogenic consensus sequences (ICS) from a comprehensive analysis of 5 738 HA-H1 and 5 396 NA-N1 sequences. These epitopes were selected because their combined epitope content is representative of greater than 84% of pre-pandemic and pandemic H1N1 influenza strains, their predicted immunogenicity (EpiMatrix) scores were greater than or equal to the 95th percentile of all comparable epitopes, and they were also predicted to be presented by more than four HLA class II archetypal alleles. We confirmed the ability of these peptides to bind in HLA binding assays and to stimulate interferon-γ production in human peripheral blood mononuclear cell cultures. These studies support the selection of the ICS as components of potential group-common H1N1 vaccine candidates and the application of this universal influenza vaccine development approach to other influenza subtypes

A strongly Lewis-acidic and fluorescent borenium cation supported by a tridentate formazanate ligand

Lewis acids are highly sought after for their applications in sensing, small-molecule activation, and catalysis. When combined with π-conjugated molecular frameworks, Lewis acids with unique optoelectronic properties can be realized. Here, we use a tridentate formazanate ligand to create a planar, redox-active, fluorescent, and strongly Lewis-acidic borenium cation. We also demonstrate that this compound can act as a colourimetric probe for reactivity

Conformal Robotic Stereolithography

Additive manufacturing by layerwise photopolymerization, commonly called stereolithography (SLA), is attractive due to its high resolution and diversity of materials chemistry. However, traditional SLA methods are restricted to planar substrates and planar layers that are perpendicular to a single-axis build direction. Here, we present a robotic system that is capable of maskless layerwise photopolymerization on curved surfaces, enabling production of large-area conformal patterns and the construction of conformal freeform objects. The system comprises an industrial six-axis robot and a custom-built maskless projector end effector. Use of the system involves creating a mesh representation of the freeform substrate, generation of a triangulated toolpath with curved layers that represents the target object to be printed, precision mounting of the substrate in the robot workspace, and robotic photopatterning of the target object by coordinated motion of the robot and substrate. We demonstrate printing of conformal photopatterns on spheres of various sizes, and construction of miniature three-dimensional objects on spheres without requiring support features. Improvement of the motion accuracy and development of freeform toolpaths would enable construction of polymer objects that surpass the size and support structure constraints imparted by traditional SLA systems.American Society for Engineering Education. National Defense Science and Engineering Graduate FellowshipNational Institute of Mental Health (U.S.) (University of Michigan Microfluidics in Biomedical Sciences Training Program. 5T32-EB005582)Singapore-MIT Alliance for Research and Technology (SMART

Semi-leptonic decays of heavy mesons and the Isgur-Wise function in quenched lattice QCD

The form factors for the semi-leptonic B->D and B->D* decays are evaluated in quenched lattice QCD at two different values of the coupling, beta=6.0 and 6.2. The action and the operators are fully O(a) non-perturbatively improved. The slope of the Isgur-Wise function is evaluated, and found to be rho^2=0.83^{+15+24}_{-11-1} (quoted errors are statistical and systematic respectively). Ratios of form factors are evaluated and compared to experimental determinations.Comment: 21 pages, 10 figure

Immunization with Cross-Conserved H1N1 Influenza CD4\u3csup\u3e+\u3c/sup\u3e T-Cell Epitopes Lowers Viral Burden in HLA DR3 Transgenic Mice

The emergence of the pandemic H1N1 strain of influenza in 2009 was associated with a unique w-shaped age-related susceptibility curve, with higher incidence of morbidity and mortality among young persons and lower incidence among older persons, also observed during the 1918 influenza pandemic. Pre-existing H1N1 antibodies were not cross-reactive with the prior seasonal vaccine, forcing influenza experts to scramble to develop a new vaccine specific for the pandemic virus. We hypothesized that response to T-cell epitopes that are cross-conserved between pandemic H1N1 and the 2008 seasonal influenza vaccine strains might have contributed to partial protection from clinical illness among older adults, despite the lack of cross-reactive humoral immunity. Using immunoinformatics tools, we previously identified hemagglutinin and neuraminidase epitopes that were highly conserved between seasonal and pandemic H1N1. Here, we validated predicted CD4+ T-cell epitopes for their ability to bind HLA and to stimulate interferon-γ production in peripheral blood mononuclear cells from a cohort of donors presenting with influenza-like illness during the 2009 pandemic and a separate cohort immunized with trivalent influenza vaccine in 2011. A limited-epitope heterologous DNA-prime/peptide-boost vaccine composed of these sequences stimulated immune responses and lowered lung viral loads in HLA DR3 transgenic mice challenged with pandemic 2009 H1N1 influenza. Cross-priming with conserved influenza T-cell epitopes such as these may be critically important to T cell-mediated protection against pandemic H1N1 in the absence of cross-protective antibodies