473 research outputs found

    Constraining churning and blurring in the Milky Way using large spectroscopic surveys -- an exploratory study

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    We have investigated the possibilities to quantify how much stars move in the Milky Way stellar disk due to diffuse processes (i.e. so called blurring) and due to influences from spiral arms and the bar (i.e. so called churning). To this end we assume that it is possible to infer the formation radius of a star if we know their elemental abundances and age as well as the metallicity profile of the interstellar medium at the time of the formation of the star. Using this information, coupled with orbital information derived from Gaia DR2 data and radial velocities from large spectroscopic surveys, we show that it is possible to isolate stellar samples such that we can start to quantify how important the role of churning is. We use data from APOGEE DR14, parallaxes from Gaia and stellar ages based on C and N elemental abundances in the stars. In our sample, we find that about half of the stars have experienced some sort of radial migration (based solely on their orbital properties), 10 % have likely have suffered only from churning, whilst a modest 5-7 % of stars have never experienced either churning or blurring making them ideal tracers of the original properties of the cool stellar disk. Our investigation shows that it is possible to put up a framework where we can begin to quantify churning and blurring an important. Important aspects for future work would include to investigate how selection effects should be accounted for.Comment: Paper submitted to MNRAS. Comments are welcom

    F-18 high alpha research vehicle: Lessons learned

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    The F-18 High Alpha Research Vehicle has proven to be a useful research tool with many unique capabilities. Many of these capabilities are to assist in characterizing flight at high angles of attack, while some provide significant research in their own right. Of these, the thrust vectoring system, the unique ability to rapidly reprogram flight controls, the reprogrammable mission computer, and a reprogrammable onboard excitation system have allowed an increased utility and versatility of the research being conducted. Because of this multifaceted approach to research in the high angle of attack regime, the capabilities of the F-18 High Alpha Research Vehicle were designed to cover as many high alpha technology bases as the program would allow. These areas include aerodynamics, controls, handling qualities, and propulsion

    High-throughput discovery of rare human nucleotide polymorphisms by Ecotilling

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    Human individuals differ from one another at only ∼0.1% of nucleotide positions, but these single nucleotide differences account for most heritable phenotypic variation. Large-scale efforts to discover and genotype human variation have been limited to common polymorphisms. However, these efforts overlook rare nucleotide changes that may contribute to phenotypic diversity and genetic disorders, including cancer. Thus, there is an increasing need for high-throughput methods to robustly detect rare nucleotide differences. Toward this end, we have adapted the mismatch discovery method known as Ecotilling for the discovery of human single nucleotide polymorphisms. To increase throughput and reduce costs, we developed a universal primer strategy and implemented algorithms for automated band detection. Ecotilling was validated by screening 90 human DNA samples for nucleotide changes in 5 gene targets and by comparing results to public resequencing data. To increase throughput for discovery of rare alleles, we pooled samples 8-fold and found Ecotilling to be efficient relative to resequencing, with a false negative rate of 5% and a false discovery rate of 4%. We identified 28 new rare alleles, including some that are predicted to damage protein function. The detection of rare damaging mutations has implications for models of human disease

    An Overview of the NASA F-18 High Alpha Research Vehicle

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    This paper gives an overview of the NASA F-18 High Alpha Research Vehicle. The three flight phases of the program are introduced, along with the specific goals and data examples taken during each phase. The aircraft configuration and systems needed to perform the disciplinary and inter-disciplinary research are discussed. The specific disciplines involved with the flight research are introduced, including aerodynamics, controls, propulsion, systems, and structures. Decisions that were made early in the planning of the aircraft project and the results of those decisions are briefly discussed. Each of the three flight phases corresponds to a particular aircraft configuration, and the research dictated the configuration to be flown. The first phase gathered data with the baseline F-18 configuration. The second phase was the thrust-vectoring phase. The third phase used a modified forebody with deployable nose strakes. Aircraft systems supporting these flights included extensive instrumentation systems, integrated research flight controls using flight control hardware and corresponding software, analog interface boxes to control forebody strakes, a thrust-vectoring system using external post-exit vanes around axisymmetric nozzles, a forebody vortex control system with strakes, and backup systems using battery-powered emergency systems and a spin recovery parachute
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