6 research outputs found

    Test of doors obstruction detection sensor

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    In bus and train transport there are a number of requirements for the safety of the entrance door. For example there are requirements to provide obstruction detection within the door system. This should reverse the movement of the door should a passenger or some other obstruction restrict the doors operation. In case the door movement is realized by a pneumatic cylinder, obstruction detection can be achieved either by using a sensitive edge or by sensing of the door actuator pressure. Detection valve providing an electrical or pneumatic output signal to the door control system to initiate door opening. The pinching time of the subject or person must not exceed 1 s. This article describes the main safety requirements for door systems of intercity traffic trains and, above all, experimental verification of obstruction detection valve behaviour.Web of Science20192901289

    Valve control of drive with rotary hydraulic motor

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    The paper describes the analysis of a valve control of a drive with a rotary hydraulic motor. The valve control is realized by a throttle valve. The individual drive characteristics are measured on the experimental device, i.e. the control and the torquespeed characteristics. The experimentally determined characteristics are compared to the theoretically calculated characteristics. Subsequently, the efficiencies of the tested rotary hydraulic motor are experimentally determined, i.e. the volumetric, mechanical-hydraulic and total efficiencies. The theoretical computational equations are subsequently supplemented by the experimentally determined efficiencies of the hydraulic motor. Theoretically determined characteristics of the drive, including efficiencies of the hydraulic motor, are again compared to the experimentally determined characteristics. The mathematical model of the experimental device is also assembled. This mathematical model is verified in a steady state.Web of Science20192909290

    Meranie stratových prietokov tekutinových prvkov

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    Import 20/04/2006Prezenční výpůjčkaVŠB - Technická univerzita Ostrava. Fakulta strojn

    Ochrana pred COVID-19 ako výzva pre technické a spoločenské vedy: Identifikácia vybraného výskumného problému aplikovaného výskum

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    The international community is making increased efforts to tackle the global pandemic of the COVID-19 virus, which is destroying society’s highest protected interest - human lives and endangering the population. The economy of each state are also secondarily affected. Some sectors have created and are creating a potential threat to support the spread of the corona virus. Unfortunately, the Transport sector and the Air Transport sub-sector are among such entities. The article presents the first part of a research study aimed at identifying the research problem of applied research in air transport and a description of the research intention to solve the problem

    The kinetics of the reaction of Octopus vulgaris hemocyanin with cyanide. Its significance for the structure of the 11 S subunit of molluscan hemocyanin.

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    Native Octopus vulgaris hemocyanin (Hc) reacts with cyanide stepwise. The first step involves the formation of a complex HcCN with O2 displacement. This complex reacts further with cyanide causing the removal of one copper ion from the active site. The same reaction sequence occurs for the extraction of the second metal ion. The formation of the HcCN complex and the removal of the first and the second copper ion can be differentiated according to the KCN concentration. The rate of metal removal is slightly affected by KCN concentration. The kinetics are dominated by site-site interactions. The kinetic curves show only slight differences when the protein is in the 11 S or 49 S aggregation states, suggesting that the site-site interactions are restricted mainly within the 11 S structure. A kinetic model describing the removal of the first copper ion is proposed assuming that the 11 S component (MW 250,000) is an annular-shaped structure made by five equivalent functional subunits (MW 50,000). An explanation for the incomplete copper removal from molluscan Hc is given. The results are compared with those previously reported for Carcinus maenas Hc

    Thermosensitive Drug Delivery System SBA-15-PEI for Controlled Release of Nonsteroidal Anti-Inflammatory Drug Diclofenac Sodium Salt: A Comparative Study

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    International audienceMesoporous SBA-15 silica material was prepared by the sol–gel method and functionalized with thermosensitive polyethylenimine polymers with different molecular weight (g·mol−1): 800 (SBA-15(C)-800), 1300 (SBA-15(C)-1300) and 2000 (SBA-15(C)-2000). The nonsteroidal anti-inflammatory drug (NSAID) diclofenac sodium was selected as a model drug and encapsulated into the pores of prepared supports. Materials were characterized by the combination of infrared spectroscopy (IR), atomic force microscopy (AFM), transmission electron microscopy (TEM), photon cross-correlation spectroscopy (PCCS), nitrogen adsorption/desorption analysis, thermogravimetry (TG), differential scanning calorimetry (DSC) and small-angle X-ray diffraction (SA-XRD) experiments. The drug release from prepared matrixes was realized in two model media differing in pH, namely small intestine environment/simulated body fluid (pH = 7.4) and simulated gastric fluid (pH = 2), and at different temperatures, namely normal body temperature (T = 37 °C) and inflammatory temperature (T = 42 °C). The process of drug loading into the pores of prepared materials from the diclofenac sodium salt solutions with different concentrations and subsequent quantitative determination of released drugs was analyzed by UV-VIS spectroscopy. Analysis of prepared SBA-15 materials modified with polyethylenimines in solution showed a high ability to store large amounts of the drug, up to 230 wt.%. Experimental results showed their high drug release into the solution at pH = 7.4 for both temperatures, which is related to the high solubility of diclofenac sodium in a slightly alkaline environment. At pH = 2, a difference in drug release rate was observed between both temperatures. Indeed, at a higher temperature, the release rates and the amount of released drug were 2–3 times higher than those observed at a lower temperature. Different kinetic models were used to fit the obtained drug release data to determine the drug release rate and its release mechanism. Moreover, the drug release properties of prepared compounds were compared to a commercially available medicament under the same experimental conditions
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