42 research outputs found
Effects of CO2-H2O dilution on the characteristics of CH4-air-O2 flames
International audience Study of non-premixed turbulent flames stabilized by a swirler Control of pollutant emissions / emissions standards Improve performances of combustion plants Investigations on flame characteristics Effects of oxygen enrichment Effects of steam and CO2 dilution Effects of swirl intensit
Numerical analysis of characteristics of biogas and syngas combustion
International audienceDevelopment of modular adapted energy concept- Gasifier - multi-fuel burner - boilerCharacterization of syngas and biogas flames - Experimentally: stability, pollutant emissions, temperature - Numerically: Calculations of laminar burning velocity, flame temperature, pollutants (NOx, CO)…This poster: some results of calculation
Targeted gene sanger sequencing should remain the first-tier genetic test for children suspected to have the five common X-linked inborn errors of immunity
DATA AVAILABILITY STATEMENT : The original contributions presented in the study are included in the article/Supplementary Material. Further inquiries can be directed to the corresponding author.To address inborn errors of immunity (IEI) which were underdiagnosed in resource-limited
regions, our centre developed and offered free genetic testing for the most common IEI by
Sanger sequencing (SS) since 2001. With the establishment of The Asian Primary
Immunodeficiency (APID) Network in 2009, the awareness and definitive diagnosis of
IEI were further improved with collaboration among centres caring for IEI patients from
East and Southeast Asia. We also started to use whole exome sequencing (WES) for
undiagnosed cases and further extended our collaboration with centres from South Asia
and Africa. With the increased use of Next Generation Sequencing (NGS), we have shifted
our diagnostic practice from SS to WES. However, SS was still one of the key diagnostic
tools for IEI for the past two decades. Our centre has performed 2,024 IEI SS genetic
tests, with in-house protocol designed specifically for 84 genes, in 1,376 patients with 744
identified to have disease-causing mutations (54.1%). The high diagnostic rate after just
one round of targeted gene SS for each of the 5 common IEI (X-linked
agammaglobulinemia (XLA) 77.4%, Wiskott–Aldrich syndrome (WAS) 69.2%, X-linked chronic granulomatous disease (XCGD) 59.5%, X-linked severe combined
immunodeficiency (XSCID) 51.1%, and X-linked hyper-IgM syndrome (HIGM1) 58.1%)
demonstrated targeted gene SS should remain the first-tier genetic test for the 5 common
X-linked IEI.The Hong Kong Society for Relief of Disabled Children and Jeffrey Modell Foundation.http://www.frontiersin.org/Immunologyam2023Paediatrics and Child Healt
Recommended from our members
Experimental and numerical investigation of turbulent isothermal and reacting flows in a non-premixed swirl burner
Predictive analysis of combined burner parameter effects on oxy-fuel flames
International audienceThe present paper aims at studying the influence of burner parameters with a separated jet configuration, namely nozzles diameters and separation distance between the jets, on the flame characteristics (lift-off positions of flame and flame length). The experimental layout considers the use of OH-chemilumenescence to measure the flame characteristics for different combinations of processing conditions. The predictive analysis is based on a neural computation that considers the correlations between the inputs and the outputs of a combustion system using a configuration of separated jet. The predictive analysis show that a good agreement is found between numerical and experimental results in the case where the predictions are within the process window. The exploration of other process parameter combinations beyond that window gives less convincing results. This is mainly attributed to the fact that steady state characteristics are predicted numerically whereas it is expected experimentally that some of burner parameter combinations can lead to an increase of the parameters characterizing the flame
Recommended from our members
Detached eddy simulation of non-reacting swirling flow in a vortex burner
Recommended from our members