A growing disconnection from nature is evident in cultural products

Human connection with nature is widely believed to be in decline, even though empirical evidence on the magnitude and temporal pattern of the change is scarce. Studying works of popular culture in English throughout the 20th century and later, we document a cultural shift away from nature, beginning in the 1950s. Since then, references to nature have been decreasing steadily in fiction, song lyrics, and film storylines. No parallel decline is observed in references to the human-made environment. These findings are cause for concern, not only because they imply foregone benefits from engagement with nature, but also because cultural products are agents of socialization that can evoke curiosity, respect, and concern for the natural world

Metronidazole pharmacokinetics in geese (Anser anser domesticus) after intravenous and oral administrations

Metronidazole (MTZ) is a 5-nitroimidazole anti-bacterial and anti-protozoal drug. In human and companion animal medicine, MTZ remains widely used due to its effectiveness against anaerobic bacteria and protozoa. In farm animals, however, MTZ is currently prohibited in several countries due to insufficient data on nitroimidazoles. The purpose of this study was to assess its pharmacokinetics (PK) in geese after single intravenous (IV) and oral (PO) administrations. Fifteen-month old healthy male geese (n = 8) were used. Geese were subjected to a two-phase, single-dose (10 mg/kg IV, 50 mg/kg PO), open, longitudinal study design with a two-week washout period between the IV and PO phases. Blood was drawn from the left wing vein to heparinized tubes at 0, 0.085 (for IV only), 0.25, 0.5, 0.75, 1, 1.5, 2, 4, 6, 8, 10, 24, and 48 h. Plasma MTZ concentrations were measured using HPLC coupled to an UV detector, and the data were pharmacokinetically analyzed using PKanalix (TM) software with a non-compartmental approach. MTZ was still quantifiable and well above the LLOQ at 24 h after both routes of administration. Following IV administration, terminal elimination half-life, volume of distribution, and total clearance were 5.47 h, 767 mL/kg, and 96 mL/h/kg, respectively. For the PO route, the bioavailability was high (85%), and the mean peak plasma concentration was 60.27 mu g/mL at 1 h. When parameters were normalized for the dose, there were no statistically significant differences for any of the PK parameters between the two routes of administration. The study shows that oral administration of MTZ seems to be promising in geese, although comprehensive research on its pharmacodynamics and multiple-dose studies are necessary before its adoption in geese can be further considered

Memories of Greenlawn Cemetery

Video requires Windows Media Player, RealPlayer, or Flash Player to view.Interviewed by Dickie SelfeOriginal sponsorship by Ohio's LSTA (Library Services and Technology Act) grant program and the Center for the Study and Teaching of Writing

Teaching Delinquent Boys

Video requires Windows Media Player, RealPlayer, or Flash Player to view.Interviewed by Dickie SelfeThis story is about teaching in a "reform" school, and losing students in the 1970sOriginal sponsorship by Ohio's LSTA (Library Services and Technology Act) grant program and the Center for the Study and Teaching of Writing

Early Life in the Hilltop

Video requires Windows Media Player, RealPlayer, or Flash Player to view.Interviewed by Dickie SelfeThis story is about an Army family [that] comes to Columbus in 1959 and lives on Vaughn St. by the Christian Free Drive-In.Original sponsorship by Ohio's LSTA (Library Services and Technology Act) grant program and the Center for the Study and Teaching of Writing

G4 Solar Storm / Aurora Event of October 10th 2024

Aurora Map created in a worldwide google map with properly coordinated UTC times for all points and locations with pictures

A Validation Of Methods Used In Analyzing Original Forest Cover.

Ph.D.Biological SciencesForestryUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/126400/2/0011252.pd