135 research outputs found
Besoin communicationnel des bibliothĂšques
Une bonne communication traduit une politique, affiche une intention, orchestre une matiÚre. Pour les bibliothÚques, ses pré-requis sont exigeants et obilisent
des compétences
spécifiques. On ne
sâimprovise pas plus
communicant que
bibliothécaire
La communication culturelle décentralisée ?
Dans un contexte de concurrence accrue entre les territoires, de grands projets culturels labellisĂ©s essaiment actuellement dans de nombreuses villes europĂ©ennes. A ce titre « Luxembourg et Grande RĂ©gion, capitale europĂ©enne de la culture 2007 » est un exemple pertinent. Cet article cherche Ă mettre en Ă©vidence la complexitĂ© des interactions entre les acteurs dans le processus de mĂ©diation et Ă mieux comprendre, Ă travers lâanalyse des pratiques communicationnelles des institutions publiques, quels sont les enjeux inhĂ©rents Ă leur positionnement sociĂ©tal.Now that there is a growing competition between territories, big cultural projects which spread in numerous European cities are based on a labelled communication. "Luxemburg and Grand Region, European Capital of culture 2007" was made of a series of events which belonged to this logic. Based on the deep analysis of one of these events, the article shows how complex the protagonistsâ interactions are in the mediation process. It also highlights what is at stake in the social positioning of local authorities and higher administrative divisions
La mutation du dispositif communicationnel des universités françaises
Les Ă©volutions qui affectent en profondeur lâenseignement supĂ©rieur français englobent une transformation importante de la fonction communication dans les universitĂ©s. Dans une situation nouvelle de concurrence exacerbĂ©e, la communication fait lâobjet dâattentions nouvelles et son positionnement organisationnel, de mĂȘme que sa conception structurelle, renvoient Ă une logique marchande souvent en dĂ©calage avec la culture organisationnelle dont elle pourra avoir pour ambition de la faire Ă©voluer. Ce contexte particulier implique des mutations de lâingĂ©nierie de la communication publique des universitĂ©s qui peuvent conduire au passage dâune organisation universitaire communicante Ă une communication universitaire organisante.The evolutions deeply affecting higher education in France comprise a major transformation in how universities organize their communication process. In a new highly competitive situation, communicating has become a new focus and the way it is organized in the institution, as well as the way it is structured, refer to a commercial logic which is often out of step with the organizational culture it may have the ambition to bring some change to. The particular context implies transforming universitiesâ public communication, which could lead to the passing from a communicative organization of the university to an organizing communication of the university
OSAMOAL: optimized simulations by adapted models using asymptotic limits
We propose in this work to address the problem of model adaptation, dedicated to hyper- bolic models with relaxation and to their parabolic limit. The goal is to replace a hyperbolic system of balance laws (the so-called fine model) by its parabolic limit (the so-called coarse model), in delimited parts of the computational domain. Our method is based on the construction of asymptotic preserving schemes and on interfacial coupling methods between hyperbolic and parabolic models. We study in parallel the cases of the Goldstein-Taylor model and of the p-system with friction
1. Instaurer une culture de la communication dans les bibliothĂšques
Une des propriĂ©tĂ©s fondamentales de la communication est quâelle est inĂ©vitable : « on ne peut pas ne pas communiquer » [Watzlawick, 1972]. Cela signifie que, quoi quâelle fasse ou ne fasse pas, une bibliothĂšque produit des messages de communication. DĂ©cider que lâon va communiquer, câest engager un processus de rationalisation de lâĂ©mission de ces messages. Câest aussi accepter, a priori, les limites de cette rationalisation : processus complexe puisquâhumain, la communication ne peut ĂȘtre e..
OSAMOAL: optimized simulations by adapted models using asymptotic limits
We propose in this work to address the problem of model adaptation, dedicated to hyper- bolic models with relaxation and to their parabolic limit. The goal is to replace a hyperbolic system of balance laws (the so-called fine model) by its parabolic limit (the so-called coarse model), in delimited parts of the computational domain. Our method is based on the construction of asymptotic preserving schemes and on interfacial coupling methods between hyperbolic and parabolic models. We study in parallel the cases of the Goldstein-Taylor model and of the p-system with friction
Granocyte-colony Stimulating Factor (G-CSF) Has Significant Efficacy as Secondary Prophylaxis of Chemotherapy-induced Neutropenia in Patients with Solid Tumors: Results of a Prospective Study
Abstract. Aim: To carry out a prospective, multicenter and observational study describing prophylactic strategies [cycle delay, dose-reduction, (G-CSF) Neutropenia is a common side-effect of cancer chemotherapy in patients with solid tumors. Febrile neutropenia (FN), defined by grade 4 neutropenia and >38.0ËC fever is the complication of most concern. It is associated with severe morbidity and increased risk of mortality (1-3). A correlation between the dose/dosing schedule and neutropenia has been established for most cytotoxic agents (4, 5). However the risk of developing life-threatening complications after an episode of severe neutropenia (i.e. FN) is variable from one patient to another due to individual risk factors. Some risk factors can be considered in predicting the risk of neutropenia and are well-established in international guidelines in the primary prophylaxis setting (5, 6). These are: age (>65 years old and older), advanced disease, altered patient condition [poor performance status (PS) and/or nutritional status], preexisting condition (active infection, open wound, recent surgery), previous FN, previous irradiation to pelvis, and impaired renal or liver function. Granulocyte colony stimulating factors (G-CSF) reduce the severity and duration of neutropenia and F
Communiquer !
L'enjeu de la communication en direction des Ă©lus, des dĂ©cideurs, mais aussi des journalistes, est devenu vital pour les bibliothĂšques : il s'agit de donner Ă voir aux tutelles leurs activitĂ©s, de rendre intelligible leur stratĂ©gie de dĂ©veloppement, de construire une image institutionnelle forte. De quels moyens dispose la bibliothĂšque pour faire la preuve du bienfondĂ© de son existence ? Comment communiquer en direction d'un Ă©lu municipal ou rĂ©gional, d'un responsable politique de la bibliothĂšque ? Que peut apporter une bonne collaboration avec des journalistes, avec les partenaires naturels ou hiĂ©rarchiques au sein de l'universitĂ© ou de la collectivitĂ© territoriale ? Comment utiliser Ă bon escient les mĂ©thodes du lobbying et du marketing, ou l'emploi des rĂ©seaux sociaux ? VoilĂ quelques-unes des questions abordĂ©es ici. Une quinzaine d'auteurs d'horizons divers (des sociologues, des enseignants, des journalistes, des bibliothĂ©caires, des responsables de communicationâŠ) nous font part de leurs propres expĂ©riences, donnent des conseils mĂ©thodologiques et des outils fort utiles, en proposant de nombreux exemples et des mises en situation. Auteur de plusieurs ouvrages dans le domaine de la documentation et des sciences de l'information, Jean-Philippe Accart est actuellement directeur des bibliothĂšques de la FacultĂ© des sciences de l'UniversitĂ© de GenĂšve
Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19
IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19.
Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19.
DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 nonâcritically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022).
INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (nâ=â257), ARB (nâ=â248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; nâ=â10), or no RAS inhibitor (control; nâ=â264) for up to 10 days.
MAIN OUTCOMES AND MEASURES The primary outcome was organ supportâfree days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes.
RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ supportâfree days among critically ill patients was 10 (â1 to 16) in the ACE inhibitor group (nâ=â231), 8 (â1 to 17) in the ARB group (nâ=â217), and 12 (0 to 17) in the control group (nâ=â231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ supportâfree days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively).
CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes.
TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570
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