A New Alkaloid and Flavonoids from the Aerial Parts of Euphorbia guyoniana

One novel alkaloid, 1,5-diphenyl-3-styryl-2-pyrazoline 1, in addition with six known flavonoids namely, kaempferol, kaempferol 3-O-glucoside, kaempferol 3-rutinoside, quercetin, quercetin 3-O-glucoside, and rutin, were isolated from the aerial parts of Euphorbia guyoniana. Their structures were established on the basis of physical and spectroscopic analysis, and by comparison with the literature data.The authors are grateful to the ANDRS and DG-RSDT at the MESRS (Ministry of Scientific Research, Algeria) for the financial support.Peer Reviewe

Isoquinoline Derivatives via Stepwise Regioselective sp² and sp³ C–H Bond Functionalizations

Efficient and practically attractive stepwise ruthenium- and palladium-catalyzed regioselective C–H bond functionalizations were achieved to produce 4-substituted tetrahydroisoquinoline derivatives featuring various heteroaromatic substructures in moderate to good yields. Both ruthenium- and palladium-based catalytic processes generated nontoxic and easily separable side products