PEGylated cationic liposome - DNA nanoparticle assembly in cell culture media: pathway effects and clues to enhanced control and transfection efficiency optimization

XII Spanish-Portuguese Conference on Controlled Drug DeliveryCationic Liposome – DNA nanoparticles constitute a promising approach for safe and efficient delivery of genes for therapeutic applications. In order to be used in vivo, these particles can be coated with an inert and hydrophilic polymer, such as polyethylene-glycol (PEG), which improves blood circulation time by providing steric stabilization against removal by the immune system. In this work we study the influence of the initial salt concentration, which controls the electrostatic atraction between cationic liposomes and anionic DNA, on the structure of PEGylated CL–DNA nanoparticles.info:eu-repo/semantics/publishedVersio

Workplace abuse and harassment: the vulnerability of informal and migrant domestic workers in Portugal

Policy makers and researchers are alarmed by the pervasive substandard working conditions and mistreatment in domestic work worldwide. Using an original dataset from a sample of domestic workers in Portugal (n=684), our study explores types of abuse and harassment and tries to unveil the potential factors affecting the likelihood of having been a victim. Empirical evidence pointed to three segments of domestic workers: victims of labour abuses related to contract and wages, victims of multiple abuses including mistreatment and also psychological and sexual harassment, and a segment with no occurrence of abuse. Informal workers are more often victims of labour abuses, while migrants, especially Brazilian women, are more likely to report all types of abuse and harassment. On the other hand, carers of the elderly often suffered multiple abuses. The results suggest that despite the prevalence of labour abuses in Portugal, the most severe abuses are uncommon.info:eu-repo/semantics/acceptedVersio

Avaliação da resistência à ferrugem em progênies de cafeeiro F4 obtidas por cruzamentos de 'icatu' com catimor.

Com o objetivo de selecionar progênies de cafeeiro resistentes à ferrugem foram instalados e conduzidos experimentos em Três Pontas, São Sebastião do Paraíso e Machado. Foram avaliadas 17 progênies desenvolvidas pelo programa de Melhoramento Genético do Cafeeiro em Minas Gerais, coordenado pela EPAMIG e obtidas pelo cruzamento ?Icatu? x Catimor, e a cultivar Rubi MG 1192 utilizada como testemunha. O delineamento foi o de blocos casualizados com três repetições. Foram analisadas as características incidência da ferrugem no primeiro semestre de 2006.Os resultados obtidos permitem verificar que as progênies avaliadas apresentam variabilidade para a resistência a ferrugem, isso é confirmado pelas estimativas da herdabilidade que foram de boa magnitude, chegando até o valor de 92,8%. Essa condição aliada à baixa incidência da doença apresentada por algumas progênies, demonstrou que é possível selecionar progênies superiores em relação à resistência a ferrugem na população estudada

Typology of abuse and harassment in domestic work in Portugal

Using an original dataset, our study explores types of abuse and harassment suffered by a sample of domestic workers in Portugal (n=684). Empirical evidence based on multiple correspondence and cluster analyses pointed to three segments of domestic workers: victims of labour abuse related to contract and wages, victims of multiple abuse including mistreatment and also psychological and sexual harassment, and a segment with no occurrence of abuse. Descriptive statistics suggest migrants, especially Brazilian women, prevail in all types of abuse and harassment, but carers of the elderly are often victims of multiple abuse. Domestic workers seem to be protected from the risk of mistreatment by trust related issues and child caring.FCT

Post-Tracheal Extubation Negative Pressure Pulmonary Edema

O edema pulmonar de pressão negativa (EPPN) também descrito na literatura como edema agudo do pulmão pós-obstrutivo ou pós-extubação traqueal, é uma entidade rara, com uma incidência de aproximadamente 0.1 % em doentes anestesiados. Os autores descrevem o caso, ocorrido após extubação traqueal, de um doente submetido a orquidectomia por via laparoscópica sob anestesia geral balanceada. Relatam a fisiopatologia, o padrão radiológico e broncoscópico e as medidas terapêuticas instituídas

Competição de variedades de macaxeira (Manihot esculenta, L.) para agricultura familiar, no Município de Salvaterra, Marajó - Pa.

Edição dos Anais do XIII Congresso Brasileiro de Mandioca; VII Workshop sobre Tecnologia em Agroindústrias de Tuberosas Tropicais, Botucatu, 2009. Disponível também on-line

Effect of a peptide in cosmetic formulations for hairhumidity-control

Humidity affects hair by changing the surface texture of the fiber. In higher humidity conditions, it is verified an increase of water uptake, which causes the swelling of the hair fibers. This leads to the extension of the hair cuticles and consequent increased friction between fibers, which causes static and an increase in the volume of hair tresses. However, these changes are distinct in different types of ethnic hair, where Caucasian Brown hair evidences a higher increase in hair tresses volume. We tested the application of several climate control formulations with and without a keratinbased peptide. The hair tresses treated with the formulations containing the peptide showed reduced volume change even after several hours of high humidity conditions. Due to its chemical nature, the peptide has affinity towards the hair fiber providing long-lasting moisture resistance and allowing it application in climate control formulations

Competição de variedades de mandioca (Manihot esculenta, L.) para agricultura familiar, no Município de Salvaterra, Marajó - Pará.

Edição dos Anais do XIII Congresso Brasileiro de Mandioca; VII Workshop sobre Tecnologia em Agroindústrias de Tuberosas Tropicais, Botucatu, 2009