Tagging Two-Photon Production at the LHC

Tagging two-photon production offers a significant extension of the LHC physics programme. Effective luminosity of high-energy gamma-gamma collisions reaches 1% of the proton-proton luminosity and the standard detector techniques used for measuring very forward proton scattering should allow for a reliable extraction of interesting two-photon interactions. Particularly exciting is a possibility of detecting two-photon exclusive Higgs boson production at the LHC.Comment: 9 pages and 4 figure

The Evolving Role of Youth Workers

In reviewing the field of youth development, of which youth workers are a part, it is clear it has had a long and complex history that is intertwined with other disciplines. More recently youth workers have experienced a transformation of sorts, with youth programs in the past being seen exclusively as a place to play and have fun, whereas today’s expectations include a much broader focus on the overall positive development of young people. This evolution has been heavily influenced by a number of societal changes that have placed increasing demands on youth programs. Today’s youth workers are faced with the responsibility to promote a young person’s development which often includes supporting academic success and graduation from high school, reducing risk-taking behaviors, increasing positive health attitudes, and more. Youth workers have seen their role change dramatically over the past 20 years with greater demands and increased accountability

The Evolving Role of Youth Workers

In reviewing the field of youth development, of which youth workers are a part, it is clear it has had a long and complex history that is intertwined with other disciplines. More recently youth workers have experienced a transformation of sorts, with youth programs in the past being seen exclusively as a place to play and have fun, whereas today’s expectations include a much broader focus on the overall positive development of young people. This evolution has been heavily influenced by a number of societal changes that have placed increasing demands on youth programs. Today’s youth workers are faced with the responsibility to promote a young person’s development which often includes supporting academic success and graduation from high school, reducing risk-taking behaviors, increasing positive health attitudes, and more. Youth workers have seen their role change dramatically over the past 20 years with greater demands and increased accountability

Workplace Giving in Universities: A U.S. Case Study at Indiana University

The phenomenon of workplace giving is underexamined in the scholarly literature; philanthropic gifts by employees to their nonprofit employers have received less attention within national and transnational contexts. This study considered the association between university staff propensity toward “internal workplace giving” and donor characteristics, drawing on literature about organizational commitment and identification as a beginning for advancing theoretical understanding of employee–employer relationships and giving at both the micro-level and meso-level. The sample of 17,038 employees covered 3 years at Indiana University, an American, public, multicampus institution. Despite its specific national and cultural context, the study raises relevant issues about workplace giving. Relational and personal characteristics were found to be significant predictors for determining who donates; using these characteristics to predict giving levels, however, was less successful. The study anticipates a growing need for related research and provides direction for further methodological and theoretical approaches

Engaging Youth in Evaluation: Using Clickers for Data Collection

Now, more than ever, evaluation is an essential component for all programs. Although the need for outcome data is clear, collecting data from youth populations is often difficult, particularly among youth who are vulnerable and/or disenfranchised. While the use of paper-and-pencil (PAP) surveys is a commonly used method of data collection, different technological methods, such as online surveys, text messaging, and personal digital assistants (PDA’s), are increasingly employed in data collection efforts. This article explores the use of audience response systems (“clickers”) as an innovative data collection method that is especially suited for use with youth. In this paper we examine qualitative findings from key informant interviews regarding data collected from youth participants on a youth program quality measure using clicker technology. Findings from the study indicate that the use of clickers may increase youth engagement in and improve the efficiency of the data collection process

Detecting and Studying Higgs Bosons at a Photon-Photon Collider

We examine the potential for detecting and studying Higgs bosons at a photon-photon collider facility associated with a future linear collider. Our study incorporates realistic \gam\gam luminosity spectra based on the most probable available laser technology. Results include detector simulations. We study the cases of: a) a SM-like Higgs boson; b) the heavy MSSM Higgs bosons; c) a Higgs boson with no $WW/ZZ$ couplings from a general two Higgs doublet model.Comment: 52 pages, 26 figures, revised version with new appendi

The Higgs - photon - Z boson coupling revisited

We analyze the coupling of CP-even and CP-odd Higgs bosons to a photon and a Z boson in extensions of the Standard Model. In particular, we study in detail the effect of charged Higgs bosons in two-Higgs doublet models, and the contribution of SUSY particle loops in the minimal supersymmetric extension of the Standard Model. The Higgs-$\gamma Z$ coupling can be measured in the decay $Z \to \gamma$+Higgs at $e^+e^-$ colliders running on the Z resonance, or in the reverse process Higgs $\to Z \gamma$ with the Higgs boson produced at LHC. We show that a measurement of this coupling with a precision at the percent level, which could be the case at future $e^+e^-$ colliders, would allow to distinguish between the lightest SUSY and standard Higgs bosons in large areas of the parameter space.Comment: 18 pages LaTex + 7 figures (ps). Typo corrected in eq.(5

The Evolving Role of Youth Workers

In reviewing the field of youth development, of which youth workers are a part, it is clear it has had a long and complex history that is intertwined with other disciplines. More recently youth workers have experienced a transformation of sorts, with youth programs in the past being seen exclusively as a place to play and have fun, whereas today’s expectations include a much broader focus on the overall positive development of young people. This evolution has been heavily influenced by a number of societal changes that have placed increasing demands on youth programs. Today’s youth workers are faced with the responsibility to promote a young person’s development which often includes supporting academic success and graduation from high school, reducing risk-taking behaviors, increasing positive health attitudes, and more. Youth workers have seen their role change dramatically over the past 20 years with greater demands and increased accountability

Clostridium difficile Toxin B causes epithelial cell necrosis through an autoprocessing-independent mechanism

Clostridium difficile is the most common cause of antibiotic-associated nosocomial infection in the United States. C. difficile secretes two homologous toxins, TcdA and TcdB, which are responsible for the symptoms of C. difficile associated disease. The mechanism of toxin action includes an autoprocessing event where a cysteine protease domain (CPD) releases a glucosyltransferase domain (GTD) into the cytosol. The GTD acts to modify and inactivate Rho-family GTPases. The presumed importance of autoprocessing in toxicity, and the apparent specificity of the CPD active site make it, potentially, an attractive target for small molecule drug discovery. In the course of exploring this potential, we have discovered that both wild-type TcdB and TcdB mutants with impaired autoprocessing or glucosyltransferase activities are able to induce rapid, necrotic cell death in HeLa and Caco-2 epithelial cell lines. The concentrations required to induce this phenotype correlate with pathology in a porcine colonic explant model of epithelial damage. We conclude that autoprocessing and GTD release is not required for epithelial cell necrosis and that targeting the autoprocessing activity of TcdB for the development of novel therapeutics will not prevent the colonic tissue damage that occurs in C. difficile - associated disease