In Print

Faculty authors explore Spanish vanguard poetry, fatherhood, multi-modal learning, and more

Transparency (in journalism)

Transparency in journalism implies that journalists make practices, processes, and sources open to public scrutiny. In journalism studies, it is considered an ethical principle and norm. As a concept, transparency means a commitment to openness by individuals, institutions and organizations

Lincoln mediated: The president and the press through nineteenth–century media

© 2015 by Taylor & Francis. All rights reserved. Lincoln Mediated provides new information about a historical figure everyone thinks they know. It describes how Abraham Lincoln worked with the press throughout his political career, beginning with his service in Congress in the late 1840s, and detailing how his ties to newspapers in Illinois, New York, and Washington played a central role in the success of his presidency. Gregory A. Borchard and David W. Bulla study how Lincoln used the press to deliver his written and spoken messages, how editors reacted to the president, and how Lincoln responded to their criticism. Reviewing his public persona through the lens of international media and visually based sources, a fascinating profile emerges.The authors cite the papers of Lincoln, the letters of influential figures, and content from leading newspapers. The book also features nineteenth–century illustrations and photographs. Lincoln Mediated ties the president’s story directly to the press, illuminating his role as a writer and as a participant in making the news. Lincoln’s legacy cannot be understood without understanding the role the press played in helping shape how he was viewed. As the authors show, Lincoln was a man, not just a political figure. Lincoln Mediated is a worthy addition to Transaction\u27s Journalism series

Oral Vaccine Delivery: The Coming Age of Particulate Vaccines to Elicit Mucosal Immunity

With the evolution of different challenging diseases, there is an urgent need of vaccine development against them to save millions of lives around the world. Particlulate delivery system plays an important role by acting as self-adjuvant in form of particles and thus assisting the immunogenicity of vaccines. Particulate vaccines have shown to have improved uptake by antigen presenting cells as compared to the soluble antigen. Traditional injectable vaccines are generally poor inducers of mucosal immunity and are therefore less effective against infections at the mucosal site. Mucosal vaccines have been reported to provide additional secretory antibody mediated protection at the mucosal site of entry of the pathogen. In this chapter, we discuss the benefits of particulate drug delivery systems for oral delivery, the role of immune system in the gut, and a case study ofa novel particulate vaccine formulated into oral dissolving film for immunization via the buccal route. Key formulation components, process parameters and their biophysical characterizations have been discussed as well

ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs.

The coronavirus SARS-CoV-2 is the causative agent of the ongoing severe acute respiratory disease pandemic COVID-19. Tissue and cellular tropism is one key to understanding the pathogenesis of SARS-CoV-2. We investigate the expression and subcellular localization of the SARS-CoV-2 receptor, angiotensin-converting enzyme 2 (ACE2), within the upper (nasal) and lower (pulmonary) respiratory tracts of human donors using a diverse panel of banked tissues. Here, we report our discovery that the ACE2 receptor protein robustly localizes within the motile cilia of airway epithelial cells, which likely represents the initial or early subcellular site of SARS-CoV-2 viral entry during host respiratory transmission. We further determine whether ciliary ACE2 expression in the upper airway is influenced by patient demographics, clinical characteristics, comorbidities, or medication use, and show the first mechanistic evidence that the use of angiotensin-converting enzyme inhibitors (ACEI) or angiotensin II receptor blockers (ARBs) does not increase susceptibility to SARS-CoV-2 infection through enhancing the expression of ciliary ACE2 receptor. These findings are crucial to our understanding of the transmission of SARS-CoV-2 for prevention and control of this virulent pathogen