44 research outputs found
Production Strategies of Livestock Herders in the Grasslands of Kazakhstan: Implications for the Marketing of Fine Fibres
Goat populations have been rising in Kazakhstan over the past ten years since independence and goats are preferred by farmers trying to restock. Quality of cashmere production is the key to profitable and sustainable sales to world markets for this luxury good. However, Kazakhstan did not develop a cashmere industry in the Soviet period so today goats are sheared rather than combed and little profit is made from cashmere. Goats, as well as sheep and camels are currently multi-purpose animals providing income from sales of animals, cashmere, milk and meat. This will change as the terms of trade change for high quality cashmere and households comb for fine down
Genome-Wide Association Data Reveal a Global Map of Genetic Interactions among Protein Complexes
This work demonstrates how gene association studies can be analyzed to map a global landscape of genetic interactions among protein complexes and pathways. Despite the immense potential of gene association studies, they have been challenging to analyze because most traits are complex, involving the combined effect of mutations at many different genes. Due to lack of statistical power, only the strongest single markers are typically identified. Here, we present an integrative approach that greatly increases power through marker clustering and projection of marker interactions within and across protein complexes. Applied to a recent gene association study in yeast, this approach identifies 2,023 genetic interactions which map to 208 functional interactions among protein complexes. We show that such interactions are analogous to interactions derived through reverse genetic screens and that they provide coverage in areas not yet tested by reverse genetic analysis. This work has the potential to transform gene association studies, by elevating the analysis from the level of individual markers to global maps of genetic interactions. As proof of principle, we use synthetic genetic screens to confirm numerous novel genetic interactions for the INO80 chromatin remodeling complex
Organizational resilience and the relationship with six major crisis types for Dutch safety regions
An emergency response organization is resilient when it learns from and is well equipped to handle (potential) risks and hazards. In this paper, we will address the organizational resilience fit for Dutch emergency response organizations (safety regions) in relation to various types of crisis. The approach presented in this paper is based on a quantitative organizational resilience model. We validated the model by means of a survey conducted among the employees of Dutch safety regions. In this survey, we queried how the employees perceive the different attributes related to a set of crisis types. We used the results to calculate the quantitative representation of organizational resilience. We found that the presence of a Quality Management system or a Safety Management system does not significantly influence the organizational resilience of the organization. However, a statistically significant difference for organizational resilience was found in the type of staff assignment: volunteer, professional, or volunteer and professional. The volunteers rated the organizational resilience lower. We recommend to increase a safety region’s organizational resilience by enhancing communication and organizational engagement of volunteers, stop pursuing a Quality/Safety Management program and perform further research on (international) emergency response organizations