Pulmonary Air Embolism in a Patient with COVID-19 with Extracorporeal Membrane Oxygenation Support

Embòlia aèria pulmonar; COVID-19Embolia aérea pulmonar; COVID-19Pulmonary air embolism; COVID-1

Case report: Cytokine hemoadsorption in a case of hemophagocytic lymphohistiocytosis secondary to extranodal NK/T-cell lymphoma

Cytokine hemoadsorption; Hemophagocytic lymphohistiocytosis; Multiorgan dysfunctionHemoadsorció de citocines; Limfohistiocitosi hemofagocítica; Disfunció multiorgànicaHemoadsorción de citoquinas; Linfohistiocitosis hemofagocítica; Disfunción multiorgánicaWe discuss a single case of Hemophagocytic lymphohistiocytosis (HLH) due to NK-type non-Hodgkin lymphoma and Epstein-Barr virus reactivation with multiorgan dysfunction and distributive shock in which we performed cytokine hemoadsorption with Cytosorb ®. A full microbiological panel was carried out, including screening for imported disease, standard serologies and cultures for bacterial and fungal infection. A liver biopsy and bone marrow aspirate were performed, confirming the diagnosis. The patients fulfilled the HLH-2004 diagnostic criteria, and according to the 2018 Consensus Statements by the HLH Steering Committee of the Histiocyte Society, dexamethasone and etoposide were started. There was an associated hypercytokinemia and, due to refractory distributive shock, rescue therapy with cytokine hemoadsorption was performed during 24 h (within day 2 and 3 from ICU admission). After starting this procedure, rapid hemodynamic control was achieved with a significant reduction in vasopressor support requirements. This case report highlights that cytokine hemoadsorption can be an effective since rapid decrease in IL-10 levels and a significant hemodynamic improvement was achieved

Негайний вплив сухого голковколювання на м’язову силу нижніх кінцівок у спортсменів, які займаються кросфітом, із латентними тригерними точками: рандомізоване потрійно сліпе пілотне клінічне дослідження

Study purpose. The purpose of this study was to evaluate the acute effect of deep dry needling (DP) on lower-limb muscle strength-related variables in CrossTraining recreational athletes with latent trigger point (TrP). Materials and methods. A total of 19 healthy CrossFit®-trained males (27.8 [4.7] years; 79.8 [10.4] kg; 1.76 [0.07] cm) with myofascial TrP in quadriceps, gluteus or gastrocnemius muscles completed this repeated-measures triple-blind pilot clinical trial. Participants were randomly allocated into either experimental (EG, n = 10) or Sham (SG, n = 9) groups. After allocation, the assessment of lower-limb muscle power (squat jump [SJ] and countermovement jump [CMJ]) and maximal isometric hip abduction and quadriceps strength were measured at baseline and after 48 hours of the intervention. Results. The results are expressed as Δ (SD) [95% CI]; unbiased Cohen’s d [dunb, 95% CI]). DN has been shown to reduce the presence of muscle TrP. The maximal isometric hip abduction strength had a moderate-to-high significant increase in the EG (left: 21.5 (16.9) [9.42, 33.57]; 0.55 [0.19, 0.99], right: 20.3 (16.2) [8.70, 31.89]; 0.74 [0.25, 1.35]); however, the Sham group only showed significant improvement in the left hip abductor muscles 15.77 (15.37) [3.96, 27.59]; 0.57 [0.11, 1.12]) with no significant changes in the right side. Conclusions. The acute reduction of myofascial TrP was observed with the application of DN but had no significant effect on maximal isometric strength or jump height compared to the Sham group. Results of this pilot clinical trial can be used to commission future research.Мета дослідження. Мета цього дослідження полягала в оцінці негайного впливу глибокого сухого голковколювання на змінні, пов’язані із силою м’язів нижніх кінцівок, у спортсменів-любителів, які займаються крос-тренінгом, із латентною тригерною точкою. Матеріали та методи. Це потрійно сліпе пілотне клінічне дослідження з повторними вимірюваннями пройшли загалом 19 здорових чоловіків, які займалися кросфітом (27,8 [4,7] року; 79,8 [10,4] кг; 1,76 [0,07] см), з міофасціальною тригерною точкою в чотириголовому, сідничному або литковому м’язах. Учасники були випадково розподілені в експериментальну групу (ЕГ, n = 10) або в контрольну групу (КП, n = 9). Після розподілу на вихідному рівні та через 48 годин після втручання оцінювали силу м’язів нижніх кінцівок (вертикальний стрибок із присіду зігнувши ноги та вертикальний стрибок із зустрічним рухом) і вимірювали силу максимального ізометричного відведення стегна та чотириголового м’яза. Результати. Результати виражені як Δ (СВ) [95% ДІ]; незміщена оцінка d Коена [dunb, 95% ДІ]). Було показано, що глибоке сухе голковколювання зменшує присутність м’язової тригерної точки. Максимальна ізометрична сила відведення стегна мала помірне або високе статистично значуще збільшення в ЕГ (лівий бік: 21,5 (16,9) [9,42, 33,57]; 0,55 [0,19, 0,99], правий бік: 20,3 (16,2) [8,70, 31,89]; 0,74 [0,25, 1,35]); однак контрольна група продемонструвала статистично значуще збільшення сили лише тих м’язів, що відводять ліве стегно (15,77 (15,37) [3,96, 27,59]; 0,57 [0,11, 1,12]), без статистично значущих змін у правому боці. Висновки. Негайне скорочення міофасціальної тригерної точки спостерігалося при застосуванні глибокого сухого голковколювання, але не мало статистично значущого впливу на максимальну ізометричну силу або висоту стрибка порівняно з контрольною групою. Результати цього пілотного клінічного дослідження можуть бути використані для підготування майбутніх досліджень

Revista Divulgación Científica Universidad del Rosario No. 6

Esta publicación tiene la decidida intención de acercar la investigación que realiza la Universidad del Rosario de Bogotá, Colombia, a un gran número de lectores para mostrarles, desde el periodismo científico, el quehacer investigativo de la institución.This publication has the determined intention of bringing the research carried out by the Universidad del Rosario in Bogotá, Colombia, to a large number of readers to show them, from scientific journalism, the investigative work of the institution

II Congreso internacional en educación física, recreación, deporte y actividad física. “Innovación y tendencias” - Memorias

El II Congreso Internacional de Educación Física, Recreación, Deporte y Actividad Física: “Innovación y Tendencias“ y el II Encuentro de Egresados del Departamento de Cultura Física de la Universidad de Córdoba se realizó en la ciudad de Montería, capital del Departamento de Córdoba, Colombia, como iniciativa del Grupo de Investigación en Ciencias de la Actividad Fisica y la Salud –GICAFS- del Departamento de Cultura Física, perteneciente a la Facultad de Educación y Ciencias Humanas de la Universidad de Córdoba, como muestra hacia la comunidad académica y la sociedad en general de la responsabilidad ética, social y profesional, para aportar a la construcción de tejido social, atendiendo a las recomendaciones del plan decenal del deporte, la Educación Física, la Recreación y la Actividad Física 2009-2019 (COLDEPORTES, 2009).Edición 201

Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study an international prospective cohort study

We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors from outside their household. The primary outcome was postoperative pulmonary complications, adjusted in multivariable models for measured confounders. Pre-defined sub-group analyses were performed for the primary outcome. A total of 96,454 patients from 114 countries were included and overall, 26,948 (27.9%) patients isolated before surgery. Postoperative pulmonary complications were recorded in 1947 (2.0%) patients of which 227 (11.7%) were associated with SARS-CoV-2 infection. Patients who isolated pre-operatively were older, had more respiratory comorbidities and were more commonly from areas of high SARS-CoV-2 incidence and high-income countries. Although the overall rates of postoperative pulmonary complications were similar in those that isolated and those that did not (2.1% vs 2.0%, respectively), isolation was associated with higher rates of postoperative pulmonary complications after adjustment (adjusted OR 1.20, 95%CI 1.05–1.36, p = 0.005). Sensitivity analyses revealed no further differences when patients were categorised by: pre-operative testing; use of COVID-19-free pathways; or community SARS-CoV-2 prevalence. The rate of postoperative pulmonary complications increased with periods of isolation longer than 3 days, with an OR (95%CI) at 4–7 days or ≥ 8 days of 1.25 (1.04–1.48), p = 0.015 and 1.31 (1.11–1.55), p = 0.001, respectively. Isolation before elective surgery might be associated with a small but clinically important increased risk of postoperative pulmonary complications. Longer periods of isolation showed no reduction in the risk of postoperative pulmonary complications. These findings have significant implications for global provision of elective surgical care. We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors from outside their household. The primary outcome was postoperative pulmonary complications, adjusted in multivariable models for measured confounders. Pre-defined sub-group analyses were performed for the primary outcome. A total of 96,454 patients from 114 countries were included and overall, 26,948 (27.9%) patients isolated before surgery. Postoperative pulmonary complications were recorded in 1947 (2.0%) patients of which 227 (11.7%) were associated with SARS-CoV-2 infection. Patients who isolated pre-operatively were older, had more respiratory comorbidities and were more commonly from areas of high SARS-CoV-2 incidence and high-income countries. Although the overall rates of postoperative pulmonary complications were similar in those that isolated and those that did not (2.1% vs 2.0%, respectively), isolation was associated with higher rates of postoperative pulmonary complications after adjustment (adjusted OR 1.20, 95%CI 1.05–1.36, p = 0.005). Sensitivity analyses revealed no further differences when patients were categorised by: pre-operative testing; use of COVID-19-free pathways; or community SARS-CoV-2 prevalence. The rate of postoperative pulmonary complications increased with periods of isolation longer than 3 days, with an OR (95%CI) at 4–7 days or ≥ 8 days of 1.25 (1.04–1.48), p = 0.015 and 1.31 (1.11–1.55), p = 0.001, respectively. Isolation before elective surgery might be associated with a small but clinically important increased risk of postoperative pulmonary complications. Longer periods of isolation showed no reduction in the risk of postoperative pulmonary complications. These findings have significant implications for global provision of elective surgical care