44 research outputs found
Exploratory study of the EU-DEMO Water-Cooled Lithium Lead breeding blanket behaviour in case of loss of cooling capability
Within the framework of the European Roadmap to the realization of fusion energy, a strong international cooperation is ongoing to develop a Breeding Blanket (BB) system for the EU-DEMO reactor. Although it is still to be decided whether the DEMO in-vessel components should perform any safety function, the pursuing of robust blanket concepts able to handle upset and accidental loading conditions has been always seen as good practice in fusion reactor engineering to enhance the inherent plant safety performances. Amongst the several classes of events that might challenge the BB structural integrity, the large Loss of Coolant Accident is one of the most relevant because it usually leads to a fast loss of cooling capability of the structures. Due to the characteristic of the tokamak assembly, the behaviour of each blanket segment during a sudden loss of cooling capability does not depend only upon distinguishing features of the component itself. In fact, the overall transient can be governed by conditions established in surrounding elements, like adjacent blanket segments and vacuum vessel, as well as by the plasma shutdown strategies adopted to protect the reactor. The scope of the activity herein presented is to make a preliminary assessment of the intrinsic capability of EU-DEMO tokamak architecture to cope with the loss of cooling in the Water-Cooled Lithium Lead (WCLL) BB concept. Evaluation of BB thermal field in short and medium term under simplified, yet conservative, assumptions was carried out for four transient scenarios with the aim of investigating the response of the structure in case of: a) fast or soft plasma shutdown, and b) different blanket cooling schemes. Moreover, the WCLL BB thermo-mechanical response in the most critical time steps has been assessed. The obtained results shall help for future decisions on safety systems/action to be implemented to cope with accidents
Determination of a pre-heating sequence for the DONES Target Assembly
Within the activities promoted by the EUROfusion consortium in support of the design and construction of the
DEMO Oriented NEutron Source (DONES), a mock-up of its Target Assembly (TA), based on the configuration
with a “bayonet” Back-Plate (BP) and available at ENEA Brasimone labs, is being adopted for the execution of
experimental activities aiming at the validation of specific aspects of the target design.
Despite the “integral”-TA concept is the current reference, experimental tests concerning the TA pre-heating
phase are not significantly affected by the TA concept and are still representative even though conducted on
the bayonet-TA concept. Indeed, the main objective of the pre-heating phase is to raise the TA temperature up to
a value close to that of the lithium flow in nominal condition (250 â—¦C). In particular, one of the main concerns is
to keep the BP at a temperature higher than 200 â—¦C to avoid possible local lithium freezing.
In order to support the afore-mentioned tests, a numerical research campaign has been launched by ENEA
Brasimone in collaboration with the University of Palermo with the goal of determining an optimal design of the
electrical heaters, both in terms of temperature set-points and geometrical layout. To this purpose, several
configurations have been assessed following a theoretical-computational approach based on the Finite Element
Method (FEM) and adopting the Abaqus FEM code. In a first phase, different electric heater layouts were assessed
by means of steady state thermal analyses. Once the most promising scenario was selected, a detailed thermal
transient analysis was carried out. An iterative procedure, based on the analysis of the maximum temperature
achieved within the mock-up most critical components, was followed in order to determine the duty cycle of the
electric heaters. The obtained numerical results are herewith reported and critically discussed
Structural assessment of the EU-DEMO water-cooled lead lithium central outboard blanket segment adopting the sub-modelling technique
The development of a sound conceptual design of the Water-Cooled Lead Lithium Breeding Blanket (WCLL BB) is pivotal to make a breakthrough towards the selection of the driver blanket concept for the EU-DEMO. To achieve this goal, an intense research campaign has been performed at the University of Palermo, in cooperation with ENEA Brasimone, under the umbrella of EUROfusion. In this paper, structural analyses of different poloidal regions of the WCLL BB Central Outboard Blanket (COB) segment are reported. In particular, starting from the results of the thermo-mechanical analysis of the whole WCLL BB COB segment, the sub-modelling technique has been applied to the most significant poloidal regions, located at the top, middle and bottom of the segment. The aim is to focus on the stress field locally arising under purposely selected steady-state nominal and accidental loading scenarios. The nominal BB operating conditions, as well as steady-state scenarios derived from both the in-box LOCA and Vertical Plasma Disruption accidents have been considered. Thanks to the sub-modelling approach, the deformative action of the entire segment can be imposed at the boundaries of each local model to realistically assess its structural performances. Moreover, each local model reproduces structural details not included in the global one, such as the Segment Box (SB) cooling channels. Then, the structural behaviour of the selected regions has been assessed in compliance with the RCC-MRx code. The obtained results highlighted that the structural behaviour predicted by the whole segment analysis is similar to that predicted by sub-modelling calculations within the Stiffening Plates, whereas the application of the sub-modelling is a must to investigate in detail the SB structural performances. In addition, results indicate that the BB attachments should be revised, as they contribute to produce the WCLL COB large deformation originating excessive stresses, mainly within the equatorial region
Development of a thermal-hydraulic model of the EU-DEMO Water Cooled Lithium Lead Breeding Blanket Primary Heat Transport System
The EUROfusion consortium is developing the project of a DEMOnstration Fusion Reactor (EU-DEMO) which would follow ITER in the pathway towards the quest for the exploitation of fusion energy. EU-DEMO has been conceived to deliver net electric power to the grid. Therefore, proper critical evaluations of the tokamak cooling and power conversion systems are needed because they play a pivotal role in the design and licencing of the overall plant. The EU-DEMO reactor will be based on the tokamak concept and, as such, it is supposed to undergo a pulsed duty cycle under normal conditions, which might challenge the qualified lifetime of the main equipment inducing undue thermal and mechanical cycling. Moreover, the EU-DEMO plasma control strategy postulates the possible occurrence of planned and off-normal plasma overpower transients that might jeopardise the structural integrity of the plasma facing components. It is, therefore, of paramount importance to have appropriate tools to reproduce the thermal-hydraulic behaviour of tokamak cooling systems during major operational and accidental scenarios in a realistic and reliable way. In this context, University of Palermo in cooperation with EUROfusion has developed a finite volume model of the Primary Heat Transport System (PHTS) feeding the EU-DEMO Water Cooled Lithium Lead Breeding Blanket (WCLL BB). The activity has been led following a theoretical–computational approach based on the adoption of the TRACE thermal-hydraulic system code. Particular attention has been paid to capturing all the main geometrical, hydraulic and heat transfer features characterising both in-vessel and ex-vessel components. Preliminary analyses have also been carried out to check the code's predictive potential in fusion relevant applications. Models, assumptions, and outcomes of the analyses are herewith reported and critically discussed
Study of the thermo-mechanical performances of the EU-DEMO Water-Cooled Lead Lithium Left Outboard Blanket segment
The development of a sound conceptual design for the Water-Cooled Lead Lithium Breeding Blanket (WCLL BB) is pivotal to make a breakthrough towards the selection of the driver blanket concept for the EU-DEMO. To this goal, a research campaign has been launched over the last years at the University of Palermo, in close cooperation with ENEA Brasimone, under the umbrella of EUROfusion. In this frame, the analysis of the thermo-mechanical behaviour of the WCLL Left Outboard Blanket (LOB) segment is being performed. In a first phase, the assessment of the segment's overall structural performances was addressed, allowing the investigation of its global response under the selected loading scenarios. On this basis, the local structural analysis of the central region and of the upper and lower regions presenting geometric discontinuities (namely those regions where the stiffeners numbers changes) is presented in this paper, with the aim of assessing in detail their structural behaviour under the nominal BB operating conditions as well as steady-state accidental loading scenarios. Adopting the sub-modelling technique, the displacement field calculated in previous LOB global structural analysis can be mapped and applied at the boundaries of each local model. Moreover, it is possible to include there some structural details missing in the global analysis, like the Segment Box cooling channels. In this way, it is possible to study the thermo-mechanical behaviour of these regions in detail, assuming at the borders the mechanical action of the rest of the structure. The assessment has been performed in compliance with the RCC-MRx code, adopting the set of criteria on the basis of the nature of the considered loading scenario. The obtained results showed a promising structural behaviour of the segment and highlighted the necessity to revise the attachment system layout, which originates excessive deformation leading to the prediction of high stress
Thermomechanical and Thermofluid-Dynamic Coupled Analysis of the Top Cap Region of the Water-Cooled Lithium Lead Breeding Blanket for the EU DEMO Fusion Reactor
In the EU, the Water-Cooled Lithium Lead (WCLL) Breeding Blanket (BB) concept is one of the candidates for the design of the DEMO reactor. From the past campaign of analysis emerged that the thermal-induced stress led to the failure in the verification of the RCC-MRx structural criteria. Hence, in this paper the classic conceptual design approach, based on a pure FEM thermal and structural analysis, is compared to a coupled thermofluid-dynamic/structural one. Even though the coupled approach requires tremendous modelling effort and computational burden, it surely allows determining the thermal field with a higher level of detail than the FEM analysis. Therefore, in this work, the focus is put on the impact of a more detailed thermal field on the DEMO WCLL BB global structural performances, focusing on the Top Cap region of its Central Outboard Blanket segment. The obtained results have allowed confirming the soundness of the design solution of the Top Cap region, except for concerns arising on the mass flow rate distribution. Moreover, results have shown that, globally, the pure FEM approach allows for obtaining more conservative results than the coupled one. This is a positive outcome in sight of the follow-up of the DEMO WCLL BB design, as it will be still possible adopting the pure FEM approach to quickly down-select design alternatives, using the most onerous coupled approach to finalise the most promising
Portal vein thrombosis and Budd-Chiari syndrome as onset of Polycythaemia Vera.
Budd-Chiari syndrome may be defined as a heterogeneous group of vascular disorders characterized by obstruction of hepatic venous return to the level of hepatic venules, supra-hepatic veins, inferior vena cava or right atrium. The main cause of this syndrome is represented by myeloproliferative diseases and, in particular, by polycythemia vera. The latter may cause multiple splanchnic thrombosis, including portal vein thrombosis, particularly important for its clinical outcomes (ascites, collateral vessels genesis, etc.). We report 2 cases of a Budd-Chiari syndrome induced by polycythemia vera characterized by an abnormal clinical onset, both as regards subjects’ age (29 and 39 years old, respectively) and set of symptoms, signs and laboratory data. After a complete clinical, instrumental and genetic diagnosis, the patients were treated with combined therapy, using acetylsalicylic acid and hydroxyurea. The therapy proved successful and patients are still in follow up in our institution. Polycythemia vera should be suspected in patients affected with portal vein thrombosis and Budd-Chiari syndrome even if its clinical onset might be unusual. Every effort should be made to make a correct and early diagnosis in order to start appropriate therapy as soon as possible and to prevent patients from useless diagnostic and therapeutic treatments
On the thermal and thermomechanical assessment of the “Optimized Conservative” helium-cooled lithium lead breeding blanket concept for DEMO
Within the framework of EUROfusion R&D activities a research campaign has been performed at CEA-Saclay, in close collaboration with the University of Palermo, in order to investigate thermal and thermomechanical performances of the “Optimized Conservative” concept of DEMO Helium-Cooled Lithium Lead breeding blanket (HCLL). Attention has been paid to the HCLL outboard equatorial module (OEM) when subjected to the steady state nominal loading scenario. To this purpose three simplified 3D models, characterized by an increasing level of detail, have been set-up taking into account, firstly, a single radial-toroidal slice, then a basic module geometric unity composed by two adjacent slices and adding, lastly, the peripheral poloidal region. This latter 3D model has allowed the assessment of the Caps potential influence on the module thermal and thermomechanical behaviour. For each investigated 3D model, thermal and thermomechanical analyses have been performed and a stress linearization procedure has been carried out in order to verify the fulfilment of the criteria prescribed by the RCC-MRx 2015 code. The study has been performed adopting a numerical approach, based on the Finite Element Method (FEM), and adopting the Siemens NX v. 10.0 software in order to discretize the geometric domain, whereas thermal and thermomechanical calculations have been carried out using the Cast3 M 2015 FEM code.The obtained results, herewith reported and critically discussed, allow predicting a good thermal and mechanical behaviour of the “Optimized Conservative” concept of DEMO HCLL OEM, even if some small modifications to the module cooling scheme should be performed in order to avoid the insurgence of hotspots where temperature is slightly above the Eurofer limit temperature (550 °C). This will entail, from the mechanical point of view, a reduction of the secondary stress amount which is the main responsible of the failure in RCC-MRx criteria verification within First Wall-Side Wall bend region
Hyaluronic acid based nanohydrogels fabricated by microfluidics for the potential targeted release of Imatinib: Characterization and preliminary evaluation of the antiangiogenic effect
Microfluidics is emerging as an innovative technique for the “on chip” fabrication of nanoparticles for drug delivery applications. Here, by using an amphiphilic derivative of hyaluronic acid as a starting macromolecule, nanohydrogels loaded with Imatinib were produced by the microfluidic procedure in order to develop an innovative therapeutic tool for the treatment of retinal neovascularization. Both cyRGDC functionalized and non-functionalized nanohydrogels were designed and fabricated by using the same technique. The targeting efficiency of the obtained nanosystems was studied in vitro on human retinal pigment epithelial cells (HRPEpiC) and human umbilical vein endothelial cells (HUVEC), the latter chosen as generic cellular model to assay inhibiting effect on cellular sprouting of Imatinib loaded nanohydrogels. The suitability of microfluidic approach for nanohydrogel production and drug loading was demonstrated. The cyRGDC functionalized nanosystems loaded with Imatinib, showed in vitro an enhanced ability to inhibit HUVEC organization into a capillary like structure
On the thermal and thermomechanical assessment of the “Optimized Conservative” helium-cooled lithium lead breeding blanket concept for DEMO
Within the framework of EUROfusion R&D activities a research campaign has been performed at CEA-Saclay, in close collaboration with the University of Palermo, in order to investigate thermal and thermomechanical performances of the “Optimized Conservative” concept of DEMO Helium-Cooled Lithium Lead breeding blanket (HCLL). Attention has been paid to the HCLL outboard equatorial module (OEM) when subjected to the steady state nominal loading scenario. To this purpose three simplified 3D models, characterized by an increasing level of detail, have been set-up taking into account, firstly, a single radial-toroidal slice, then a basic module geometric unity composed by two adjacent slices and adding, lastly, the peripheral poloidal region. This latter 3D model has allowed the assessment of the Caps potential influence on the module thermal and thermomechanical behaviour. For each investigated 3D model, thermal and thermomechanical analyses have been performed and a stress linearization procedure has been carried out in order to verify the fulfilment of the criteria prescribed by the RCC-MRx 2015 code. The study has been performed adopting a numerical approach, based on the Finite Element Method (FEM), and adopting the Siemens NX v. 10.0 software in order to discretize the geometric domain, whereas thermal and thermomechanical calculations have been carried out using the Cast3 M 2015 FEM code. The obtained results, herewith reported and critically discussed, allow predicting a good thermal and mechanical behaviour of the “Optimized Conservative” concept of DEMO HCLL OEM, even if some small modifications to the module cooling scheme should be performed in order to avoid the insurgence of hotspots where temperature is slightly above the Eurofer limit temperature (550 °C). This will entail, from the mechanical point of view, a reduction of the secondary stress amount which is the main responsible of the failure in RCC-MRx criteria verification within First Wall-Side Wall bend region