Undergraduate Knowledge of School Psychology and the Effects of Presentation on Graduate and Career Pursuit

With the increasing national demand for credentialed school psychologists, it is essential that every effort be made to recruit qualified individuals into the field of school psychology. This paper describes the important role and function of the school psychologist. Research demonstrating the present and future need for school psychological services is presented. Literature investigating several factors that contribute to the gap between supply and demand is reviewed. An intervention is presented based on the recommendations of the reviewed research. A brief informational presentation on school psychology, in conjunction with distributed materials about the profession, was assessed with a retrospective pretest-posttest design. The intervention was shown to increase undergraduates\u27 knowledge of school psychological service, the amount of information they had on school psychology as a potential career choice, and the amount of information they had on graduate training in school psychology. The intervention also significantly increased the number of students considering graduate training in school psychology. The majority of the students indicated that they planned on seeking more information about school psychology. The intervention was deemed relevant, interesting, and informative by the participants

Abridged bibliography of photographic interpretation : selected with emphasis upon keys, techniques, and research

This bibliography, PIC Report No. 102A/50, is a literature review of the applications of aerial photography. It is a classified list covering applications for archaeology, engineering, forestry, geography, geology, soil science, and the study of vegetation. The copy used to create this digital document was borrowed from the Maury Oceanographic Library, Stennis Space Center, MS

The Pan-STARRS Moving Object Processing System

We describe the Pan-STARRS Moving Object Processing System (MOPS), a modern software package that produces automatic asteroid discoveries and identifications from catalogs of transient detections from next-generation astronomical survey telescopes. MOPS achieves > 99.5% efficiency in producing orbits from a synthetic but realistic population of asteroids whose measurements were simulated for a Pan-STARRS4-class telescope. Additionally, using a non-physical grid population, we demonstrate that MOPS can detect populations of currently unknown objects such as interstellar asteroids. MOPS has been adapted successfully to the prototype Pan-STARRS1 telescope despite differences in expected false detection rates, fill-factor loss and relatively sparse observing cadence compared to a hypothetical Pan-STARRS4 telescope and survey. MOPS remains >99.5% efficient at detecting objects on a single night but drops to 80% efficiency at producing orbits for objects detected on multiple nights. This loss is primarily due to configurable MOPS processing limits that are not yet tuned for the Pan-STARRS1 mission. The core MOPS software package is the product of more than 15 person-years of software development and incorporates countless additional years of effort in third-party software to perform lower-level functions such as spatial searching or orbit determination. We describe the high-level design of MOPS and essential subcomponents, the suitability of MOPS for other survey programs, and suggest a road map for future MOPS development.Comment: 57 Pages, 26 Figures, 13 Table

1.3 mm Wavelength VLBI of Sagittarius A*: Detection of Time-Variable Emission on Event Horizon Scales

Sagittarius A*, the ~4 x 10^6 solar mass black hole candidate at the Galactic Center, can be studied on Schwarzschild radius scales with (sub)millimeter wavelength Very Long Baseline Interferometry (VLBI). We report on 1.3 mm wavelength observations of Sgr A* using a VLBI array consisting of the JCMT on Mauna Kea, the ARO/SMT on Mt. Graham in Arizona, and two telescopes of the CARMA array at Cedar Flat in California. Both Sgr A* and the quasar calibrator 1924-292 were observed over three consecutive nights, and both sources were clearly detected on all baselines. For the first time, we are able to extract 1.3 mm VLBI interferometer phase information on Sgr A* through measurement of closure phase on the triangle of baselines. On the third night of observing, the correlated flux density of Sgr A* on all VLBI baselines increased relative to the first two nights, providing strong evidence for time-variable change on scales of a few Schwarzschild radii. These results suggest that future VLBI observations with greater sensitivity and additional baselines will play a valuable role in determining the structure of emission near the event horizon of Sgr A*.Comment: 8 pages, submitted to ApJ

Pre-discovery Activity of New Interstellar Comet 2I/Borisov Beyond 5 AU

Comet 2I/Borisov, the first unambiguous interstellar comet ever found, was discovered in August 2019 at $\sim3$ au from the Sun on its inbound leg. No pre-discovery detection beyond 3 au has yet been reported, mostly due to the comet's proximity to the Sun as seen from the Earth. Here we present a search for pre-discovery detections of comet Borisov using images taken by the Catalina Sky Survey (CSS), Pan-STARRS and Zwicky Transient Facility (ZTF), with a further comprehensive follow-up campaign being presented in \citet{Bolin2019}. We identified comet Borisov in ZTF images taken in May 2019 and use these data to update its orbit. This allowed us to identify the comet in images acquired as far back as December 2018, when it was 7.8 au from the Sun. The comet was not detected in November 2018 when it was 8.6 au from the Sun, possibly implying an onset of activity around this time. This suggests that the activity of the comet is either driven by a more volatile species other than H$_2$O, such as CO or CO$_2$, or by exothermic crystallization of amorphous ice. We derive the radius of the nucleus to be $<7$ km using the non-detection in November 2018, and estimate an area of $\sim0.5$---$10 \mathrm{km^2}$ has been active between December 2018 and September 2019, though this number is model-dependent and is highly uncertain. The behavior of comet Borisov during its inbound leg is observationally consistent with dynamically new comets observed in our solar system, suggesting some similarities between the two.Comment: AJ in pres

Pre-discovery Activity of New Interstellar Comet 2I/Borisov Beyond 5 AU

Comet 2I/Borisov, the first unambiguous interstellar comet ever found, was discovered in 2019 August at ~3 au from the Sun on its inbound leg. No pre-discovery detection beyond 3 au has yet been reported, mostly due to the comet's proximity to the Sun as seen from the Earth. Here we present a search for pre-discovery detections of comet Borisov using images taken by the Catalina Sky Survey, Pan-STARRS, and the Zwicky Transient Facility (ZTF), with a further comprehensive follow-up campaign being presented in Bolin et al. We identified comet Borisov in ZTF images taken in 2019 May and use these data to update its orbit. This allowed us to identify the comet in images acquired as far back as 2018 December, when it was 7.8 au from the Sun. The comet was not detected in 2018 November when it was 8.6 au from the Sun, possibly implying an onset of activity around this time. This suggests that the activity of the comet is either driven by a more volatile species other than H₂O, such as CO or CO₂, or by exothermic crystallization of amorphous ice. We derive the radius of the nucleus to be <7 km using the non-detection in 2018 November, and estimate an area of ~0.5–10 km² has been active between 2018 December and 2019 September, though this number is model-dependent and is highly uncertain. The behavior of comet Borisov during its inbound leg is observationally consistent with dynamically new comets observed in our solar system, suggesting some similarities between the two

Publisher Correction: Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma.

The original version of this Article omitted Suzana A. Kahn, Siddhartha S. Mitra &amp; Samuel H. Cheshier as jointly supervising authors. This has now been corrected in both the PDF and HTML versions of the Article

Epidemic Leptospirosis Associated with Pulmonary Hemorrhage—Nicaragua, 1995

In October 1995, epidemic “hemorrhagic fever,” without jaundice or renal manifestations, was reported in rural Nicaragua following heavy flooding; 2259 residents were evaluated for nonmalarial febrile illnesses (cumulative incidence, 6.1%) and 15 (0.7%) died with pulmonary hemorrhage. A case-control study found that case-patients were more likely than controls to have ever walked in creeks (matched odds ratio [MOR], 15.0; 95% confidence interval [CI], 1.7–132.3), have household rodents (MOR, 10.4; 95% CI, 1.1–97.1), or own dogs with titers ≥ 400 to Leptospira species (MOR, 23.4; 95% CI, 3.6–`). Twenty-six of 51 case-patients had serologic or postmortem evidence of acute leptospirosis. Leptospira species were isolated from case-patients and potential animal reservoirs. This leptospirosis epidemic likely resulted from exposure to flood waters contaminated by urine from infected animals, particularly dogs. Leptospirosis should be included in the differential diagnosis for nonmalarial febrile illness, particularly during periods of flooding or when pulmonary hemorrhage occurs

Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma

A major limitation of targeted cancer therapy is the rapid emergence of drug resistance, which often arises through mutations at or downstream of the drug target or through intrinsic resistance of subpopulations of tumor cells. Medulloblastoma (MB), the most common pediatric brain tumor, is no exception, and MBs that are driven by sonic hedgehog (SHH) signaling are particularly aggressive and drug-resistant. To find new drug targets and therapeutics for MB that may be less susceptible to common resistance mechanisms, we used a developmental phosphoproteomics approach in murine granule neuron precursors (GNPs), the developmental cell of origin of MB. The protein kinase CK2 emerged as a driver of hundreds of phosphorylation events during the proliferative, MB-like stage of GNP growth, including the phosphorylation of three of the eight proteins commonly amplified in MB. CK2 was critical to the stabilization and activity of the transcription factor GLI2, a late downstream effector in SHH signaling. CK2 inhibitors decreased the viability of primary SHH-type MB patient cells in culture and blocked the growth of murine MB tumors that were resistant to currently available Hh inhibitors, thereby extending the survival of tumor-bearing mice. Because of structural interactions, one CK2 inhibitor (CX-4945) inhibited both wild-type and mutant CK2, indicating that this drug may avoid at least one common mode of acquired resistance. These findings suggest that CK2 inhibitors may be effective for treating patients with MB and show how phosphoproteomics may be used to gain insight into developmental biology and pathology