12 research outputs found
Modeling DNA Structure, Elasticity and Deformations at the Base-pair Level
We present a generic model for DNA at the base-pair level. We use a variant
of the Gay-Berne potential to represent the stacking energy between neighboring
base-pairs. The sugar-phosphate backbones are taken into account by semi-rigid
harmonic springs with a non-zero spring length. The competition of these two
interactions and the introduction of a simple geometrical constraint leads to a
stacked right-handed B-DNA-like conformation. The mapping of the presented
model to the Marko-Siggia and the Stack-of-Plates model enables us to optimize
the free model parameters so as to reproduce the experimentally known
observables such as persistence lengths, mean and mean squared base-pair step
parameters. For the optimized model parameters we measured the critical force
where the transition from B- to S-DNA occurs to be approximately . We
observe an overstretched S-DNA conformation with highly inclined bases that
partially preserves the stacking of successive base-pairs.Comment: 15 pages, 25 figures. submitted to PR
Share and share alike or Winner take all?: The influence of social value orientation upon choice and recall of negotiation heuristics
Two experiments test the hypothesis that social value orientation influences choice and recall of heuristics in individuals preparing for negotiation. Consistent with predictions, Study 1 shows that in the preparation phase, negotiators with a prosocial value orientation choose more cooperative heuristics (e.g., "equal split is fair") than competitive heuristics (e.g., "your gain is my loss") while negotiators with a competitive social value orientation do the reverse. Negotiators with an individualistic social value orientation do not discriminate in their choice between cooperative and competitive heuristics. Study 2 shows that following preparation, prosocial negotiators recall more cooperative than competitive heuristics while individualists and competitors do the reverse. Additional measures suggest that prosocial negotiators prefer cooperative heuristics because these are seen as morally appropriate, whereas individualists and competitors prefer competitive heuristics because these are seen as effective
Alternative reference points and outcome evaluation: The influence of affect
10.1037/a0024891Journal of Applied Psychology97133-45JAPG