Clinical Value of the Postpacing Interval for Mapping of Ventricular Tachycardia in Patients with Prior Myocardial Infarction

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72569/1/j.1540-8167.1999.tb00640.x.pd

Radiofrequency Ablation of Idiopathic Left Anterior Fascicular Tachycardia

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/71580/1/j.1540-8167.1995.tb00389.x.pd

Extending the limits of globule detection -- ISOPHOT Serendipity Survey Observations of interstellar clouds

A faint $I_{\rm 170}=4$ MJysr$^{-1}$ bipolar globule was discovered with the ISOPHOT 170 $\mu$m Serendipity Survey (ISOSS). ISOSS J 20246+6541 is a cold ($T_{\rm d}\approx 14.5$ K) FIR source without an IRAS pointsource counterpart. In the Digitized Sky Survey B band it is seen as a 3\arcmin size bipolar nebulosity with an average excess surface brightness of $\approx 26$ mag/$\square$\arcsec . The CO column density distribution determined by multi-isotopic, multi-level CO measurements with the IRAM-30m telescope agrees well with the optical appearance. An average hydrogen column density of $\approx 10^{21}$cm$^{-2}$ was derived from both the FIR and CO data. Using a kinematic distance estimate of 400 pc the NLTE modelling of the CO, HCO$^+$, and CS measurements gives a peak density of $\approx 10^4$cm$^{-3}$. The multiwavelength data characterise ISOSS 20246+6541 as a representative of a class of globules which has not been discovered so far due to their small angular size and low 100$\mu$m brightness. A significant overabundance of $^{13}$CO is found $X(^{13}CO) \ge 150\times X(C^{18}O)$. This is likely due to isotope selective chemical processes.Comment: 5 pages, 3 figure

Solar System Objects in the ISOPHOT 170 micron Serendipity Survey

The ISOPHOT Serendipity Survey (ISOSS) covered approximately 15 % of the sky at a wavelength of 170 micron while the ISO satellite was slewing from one target to the next. By chance ISOSS slews went over many solar system objects (SSOs). We identified the comets, asteroids and planets in the slews through a fast and effective search procedure based on N-body ephemeris and flux estimates. The detections were analysed from a calibration and scientific point of view. Through the measurements of the well-known asteroids Ceres, Pallas, Juno and Vesta and the planets Uranus and Neptune it was possible to improve the photometric calibration of ISOSS and to extend it to higher flux regimes. We were also able to establish calibration schemes for the important slew end data. For the other asteroids we derived radiometric diameters and albedos through a recent thermophysical model. The scientific results are discussed in the context of our current knowledge of size, shape and albedos, derived from IRAS observations, occultation measurements and lightcurve inversion techniques. In all cases where IRAS observations were available we confirm the derived diameters and albedos. For the five asteroids without IRAS detections only one was clearly detected and the radiometric results agreed with sizes given by occultation and HST observations. Four different comets have clearly been detected at 170 micron and two have marginal detections. The observational results are presented to be used by thermal comet models in the future. The nine ISOSS slews over Hale-Bopp revealed extended and asymmetric structures related to the dust tail. We attribute the enhanced emission in post-perihelion observations to large particles around the nucleus. The signal patterns are indicative of a concentration of the particles in trail direction.Comment: 15 pages, 6 figures, 6 tables; Accepted for publication in Astronomy and Astrophysic

Effect of Dust Extinction on Estimating Star Formation Rate of Galaxies: Lyman Continuum Extinction

We re-examine the effect of Lyman continuum ($\lambda \leq 912$ \AA) extinction (LCE) by dust in H {\sc ii} regions in detail and discuss how it affects the estimation of the global star formation rate (SFR) of galaxies. To clarify the first issue, we establish two independent methods for estimating a parameter of LCE ($f$), which is defined as the fraction of Lyman continuum photons contributing to hydrogen ionization in an H {\sc ii} region. One of those methods determines $f$ from the set of Lyman continuum flux, electron density and metallicity. In the framework of this method, as the metallicity and/or the Lyman photon flux increase, $f$ is found to decrease. The other method determines $f$ from the ratio of infrared flux to Lyman continuum flux. Importantly, we show that f \la 0.5 via both methods in many H {\sc ii} regions of the Galaxy. Thus, it establishes that dust in such H {\sc ii} regions absorbs significant amount of Lyman continuum photons directly. To examine the second issue, we approximate $f$ to a function of only the dust-to-gas mass ratio (i.e., metallicity), assuming a parameter fit for the Galactic H {\sc ii} regions. We find that a characteristic $\hat{f}$, which is defined as $f$ averaged over a galaxy-wide scale, is 0.3 for the nearby spiral galaxies. This relatively small $\hat{f}$ indicates that a typical increment factor due to LCE for estimating the global SFR ($1/\hat{f}$) is large ($\sim 3$) for the nearby spiral galaxies. Therefore, we conclude that the effect of LCE is not negligible relative to other uncertainties of estimating the SFR of galaxies.Comment: 18 papges, 11 figures, accepted by Ap

Efficient Numerical Schemes for Computing Cardiac Electrical Activation over Realistic Purkinje Networks: Method and Verification

We present a numerical solver for the fast conduction system in the heart using both a CPU and a hybrid CPU/GPU implementation. To verify both implementations, we construct analytical solutions and show that the L2-error is similar in both implementations and decreases linearly with the spatial step size. Finally, we test the performance of the implementations with networks of varying complexity, where the hybrid implementation is, on average, 5.8 times faster

An infrared-submillimeter study of star-forming regions selected by the ISOSS 170um survey

Using the ISOPHOT Serendipity Survey (ISOSS) at 170um a sample of galactic star-forming regions exhibiting very cold dust temperatures (< 20 K) and high masses (> 100 M_sun) has been established. We characterise the star-forming content of five regions that were selected as potential sites for early stage high-mass star formation using SCUBA (JCMT) and Spitzer observations. In every region we identify one to four submillimeter clumps with projected sizes between 0.1 and 0.4 pc. The dust temperatures range from 11.6 to 21.3 K and the estimated clump masses are 2 to 166 M_sun. Towards the majority of submillimeter peaks we find point sources in the near- to mid-infrared. Most are interpreted as low-mass young stellar objects but we also detect very red sources. They probably represent very young and deeply embedded protostars that continue to accrete clump material and may reach higher masses. Several candidate intermediate-mass proto- or pre-main-sequence stars embedded in the clumps are identified. A subset of four clumps may be massive enough (> 100 M_sun) to form high-mass stars and accompanying clusters. The absence of stellar precursors with current masses in the high-mass regime leave the type of star formation occuring in the clumps unsettled. We confirm the presence of large fractions of cold material as derived from large-scale far-infrared measurements which dominates the emission of most clumps and suggests that the star-forming process will continue.Comment: 11 pages, 11 figures, accepted for publication in A&

Electrophysiology Model for a Human Heart with Ischemic Scar and Realistic Purkinje Network

The role of Purkinje fibres in the onset of arrhythmias is controversial and computer simulations may shed light on possible arrhythmic mechanisms involving the Purkinje fibres. However, few computational modelling studies currently include a detailed Purkinje network as part of the model. We present a coupled Purkinje-myocardium electrophysiology model that includes an explicit model for the ischemic scar plus a detailed Purkinje network, and compare simulated activation times to those obtained by electro-anatomical mapping in vivo during sinus rhythm pacing. The results illustrate the importance of using sufficiently dense Purkinje networks in patient-specific studies to capture correctly the myocardial early activation that may be influenced by surviving Purkinje fibres in the infarct region