Evidences for the existence of glycoproteins and mucopolysaccharides metabolic cycles in the cerebellum of birds and mammals.

Cerebellum glycoproteins of rats and ducks are studied using sugar-specific agglutinins. It is used the Con A-Peroxidase-DAB technique described by Bernhard and Avrameas (1971). Other agglutinins (Tetragonolobus Purpureus Lectin, Wheat Germ Agglutinin and Soybean Agglutinin) fixed to Peroxidase according to the technique of Gonatas and Avrameas (1973) are also used. The techniques for mucopolysaccharides as described Martínez-Rodriguez et al., (1976) are carried out as well. By means of all these techniques, results that suggest the existence of metabolic cycles in Purkinje cells are obtained.Peer Reviewe

Localised impedance monitoring device for the remote clinical assessment of home-based dialysis patients

International audienc

The Complicating Effects of Patient Limb Position on the Development of a Localised Impedimetric-Based Hydrational Index for the Remote Monitoring of Home-Based Dialysis Patients

International audienceBioimpedance measurements have been used to assess the effects of haemodialysis on patients and to help determine when the desired “dry weight” has been achieved and hence the optimum moment to stop the procedure.In the present research project we seek to develop a localised (on the calf), integrated measurement system capable of transmitting hydration-related impedimetric data, periodically between dialysis sessions, from patients undergoing home-based treatment to a remote monitoring clinic.We have found that the effects of the subject simply lying or sitting down gives rise to fluid changes in the calf which appear as significant and as long lasting as those due to the haemodialysis procedure itself.If correct, these preliminary findings will necessitate careful consideration of these two, possibly competing, effects on the determination of, for example, the moment the desired “dry weight” has been achieved during clinical haemodialysis treatments.Measures are being taken to address this problem in our own remote monitoring of the wellbeing of home-based dialysis patients