14 research outputs found
Transport Service Quality And Social Responsibility Through The Relationship Marketing
This paper focuses on marketing for passenger transport based on the research concerned with urban sustainable development and mobility issues and it is oriented to the conceptual discussion of Relationship Marketing to be adopted in transport policy in consonance of another productive sectors. At first, there are made comments on reasons for development of marketing strategies applications, necessary all over the world. Although some differences between the developed and developing countries are picked out, it becomes evident that new approach for marketing passenger transport is necessary and quite urgent, giving that it should be oriented not only to the market behavior, but also it should involve different actors being called to social accountability. A short review of state-of-the-art and state-of-the-practice in transport marketing, analyzing some critical aspects inherited to the transit service marketing, provides also comments on outstanding importance of social and economic activities as determinants for travel needs and travel behavior. In this context it is brought up a concept of Relationship Marketing, conceived from service marketing field. The main characteristics of this concept consist in pro-active behavior of different, public and private actors, including consumers, local communities, public agencies, transit operators, and non transport businesses. This kind of co-marketing, based on partnership, results in provision of service packages, comprising basic, facilitating, and supporting services, adapted to the clientcitizens needs, trying to retain them on transit. This approach, build on spatial activities network partnership, seems to have a good potential for urban management applications. There is also commented an Integrated Mobility Management Model based on Relationship Marketing, which tripartite framework should articulate management of activities production and accessibility production, both oriented to the client-citizens consumption and welfare
Conceiving Competitive Arrangements For Public Transport
Institute of Transport and Logistics Studies. Faculty of Economics and Business. The University of Sydne
Prague Integrated Transport
Institute of Transport and Logistics Studies. Faculty of Economics and Business. The University of Sydne
Perception Of Potential Partners For Car Withdrawal From Urban Transport
Institute of Transport and Logistics Studies. Faculty of Economics and Business. The University of Sydne
Joint Development Feasibility Of A Greening Transport Alternative
Institute of Transport and Logistics Studies. Faculty of Economics and Business. The University of Sydne
Complex SUMO-1 Regulation of Cardiac Transcription Factor Nkx2-5
Reversible post-translational protein modifications such as SUMOylation add complexity to cardiac transcriptional regulation. The homeodomain transcription factor Nkx2-5/Csx is essential for heart specification and morphogenesis. It has been previously suggested that SUMOylation of lysine 51 (K51) of Nkx2-5 is essential for its DNA binding and transcriptional activation. Here, we confirm that SUMOylation strongly enhances Nkx2-5 transcriptional activity and that residue K51 of Nkx2-5 is a SUMOylation target. However, in a range of cultured cell lines we find that a point mutation of K51 to arginine (K51R) does not affect Nkx2-5 activity or DNA binding, suggesting the existence of additional Nkx2-5 SUMOylated residues. Using biochemical assays, we demonstrate that Nkx2-5 is SUMOylated on at least one additional site, and this is the predominant site in cardiac cells. The second site is either non-canonical or a “shifting” site, as mutation of predicted consensus sites and indeed every individual lysine in the context of the K51R mutation failed to impair Nkx2-5 transcriptional synergism with SUMO, or its nuclear localization and DNA binding. We also observe SUMOylation of Nkx2-5 cofactors, which may be critical to Nkx2-5 regulation. Our data reveal highly complex regulatory mechanisms driven by SUMOylation to modulate Nkx2-5 activity
GERENCIAMENTO DE TRANSPORTE COLETIVO
Trata-se da primeira produção acadĂŞmica voltada para as necessidades do setor de transporte de passageiros. O trabalho, destinado nĂŁo sĂł aos executivos das empresas, como tambĂ©m aos tĂ©cnicos, aos pesquisadores e consultores da área de transporte de passageiros, traz no seu bojo a preocupação de aproximar as contribuições teĂłricas ao estado da prática nas empresas operadoras. O livro, atravĂ©s dos seus oito capĂtulos, abre as portas para os tĂłpicos que devem ser considerados essenciais para as possibilidades de aperfeiçoamento e modernização gerencial